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Results for "

Hair Inhibitors

" in MedChemExpress (MCE) Product Catalog:

By Targets:	15-PGDH (1) 5 alpha Reductase (1) Amyloid-β (1) Androgen Receptor (1) Apoptosis (2) Biochemical Assay Reagents (1) Calcium Channel (1) Caspase (2) Cytochrome P450 (2) DNA/RNA Synthesis (1) EGFR (1) Endogenous Metabolite (2) Fungal (2) GSK-3 (1) Histamine Receptor (1) IGF-1R (1) JAK (3) Mitochondrial Metabolism (2) Parasite (4) Phytohormone (1) PI3K (1) Platelet-activating Factor Receptor (PAFR) (1) Potassium Channel (3) PROTACs (1) Reactive Oxygen Species (1) γ-secretase (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (3) Endocrinology (3) Infection (4) Inflammation/Immunology (5) Metabolic Disease (3) Neurological Disease (4)

By Targets:

15-PGDH (1)

5 alpha Reductase (1)

Amyloid-β (1)

Androgen Receptor (1)

Apoptosis (2)

Biochemical Assay Reagents (1)

Calcium Channel (1)

Caspase (2)

Cytochrome P450 (2)

DNA/RNA Synthesis (1)

EGFR (1)

Endogenous Metabolite (2)

Fungal (2)

GSK-3 (1)

Histamine Receptor (1)

IGF-1R (1)

JAK (3)

Mitochondrial Metabolism (2)

Parasite (4)

Phytohormone (1)

PI3K (1)

Platelet-activating Factor Receptor (PAFR) (1)

Potassium Channel (3)

PROTACs (1)

Reactive Oxygen Species (1)

γ-secretase (1)

By Research Areas:

Cancer (9)

Cardiovascular Disease (3)

Endocrinology (3)

Infection (4)

Inflammation/Immunology (5)

Metabolic Disease (3)

Neurological Disease (4)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Serpin

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-125616

Biotinoyl tripeptide-1 Biotinyl-GHK; Bio-GHK	Amyloid-β Reactive Oxygen Species	Others Neurological Disease
Biotinoyl tripeptide-1 (Biotinyl-GHK) is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases .

HY-B0744

Eflornithine Maximum Cited Publications 12 Publications Verification DFMO; MDL71782; RMI71782; α-difluoromethylornithine	Parasite	Infection Cancer
Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.

HY-B0744A

Eflornithine hydrochloride Maximum Cited Publications 12 Publications Verification DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride	Parasite	Infection Cancer
Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.

HY-B0744B

Eflornithine hydrochloride hydrate Maximum Cited Publications 12 Publications Verification DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate	Parasite	Cancer
Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .

HY-50856S

Deuruxolitinib CTP-543; Ruxolitinib d₈; Deuterated Ruxolitinib	JAK	Inflammation/Immunology
Deuruxolitinib, a deuterated Ruxolitinib (HY-50856), is an orally active JAK1 and JAK2 inhibitor. Deuruxolitinib demonstrates significant hair regrowth effects. Deuruxolitinib can be used for the research of alopecia areata .

HY-149296

JAK1-IN-12	JAK	Inflammation/Immunology
JAK1-IN-12 is a selective inhibitor of JAK1, with IC₅₀ of 0.0246 μM. And IC₅₀s of 0.423 μM, 0.410 μM and 1.12 μM for JAK2, JAK3 and TYK2. JAK1-IN-12 promotes hair growth in mice. JAK1-IN-12 can be used for research of immune and inflammatory diseases .

HY-162831

MPC-IN-1	Mitochondrial Metabolism	Others
MPC-IN-1 (compound 4i) is a cyanocinnamate-based, mitochondrial pyruvate transporter (MPC) inhibitor, and is a derivative of UK-5099 (HY-15475). MPC inhibitors promote the development of hair follicle stem cells without affecting normal cells. MPC-IN-1 promotes cellular lactate production and promotes significant hair growth in mice, and has the potential to be used to inhibit hair loss .

HY-N7229

Rabdosin B	DNA/RNA Synthesis	Cancer
Rabdosin B is an ent-kaurene diterpenoid with anticancer effects. Rabdosin B induces DNA damage in cells, and inhibits lettuce root hair development of seedlings .

HY-158012

LY3056480	γ-secretase	Others
LY3056480 is a gamma-secretase inhibitor (GSI) that inhibits Notch signaling. LY3056480 improves mild to moderate sensorineural hearing loss and is safe and tolerable. Intratympanic administration of LY3056480 induces hair cell regeneration and partial hearing recovery in mammals .

HY-B0744BR

Eflornithine (hydrochloride hydrate) (Standard)	Parasite	Cancer
Eflornithine (hydrochloride hydrate) (Standard) is the analytical standard of Eflornithine (hydrochloride hydrate). This product is intended for research and analytical applications. Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women .

HY-B0112

Minoxidil 5+ Cited Publications U10858	Potassium Channel Endogenous Metabolite	Cardiovascular Disease Cancer
Minoxidil (U10858) is an ATP-sensitive potassium (K_ATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC₅₀ of 20 μM .

HY-W127549

Petroselinic acid sodium cis-6-Octadecenoic acid	Biochemical Assay Reagents	Others
Petroselinic acid sodium is an organic compound belonging to the class of carboxylic acids. Petroselinic acid sodium has several applications in the cosmetic and personal care industries, especially as an emulsifier and conditioning agent in skin and hair care products. In addition, it has potential utility in inhibiting inflammation-related diseases and cancer.

HY-116198

15-PGDH-IN-2	15-PGDH	Metabolic Disease
15-PGDH-IN-2 (Compound 2) is a 15-PGDH inhibitor with an IC₅₀ value of 0.274 nM. 15-PGDH-IN-2 can be used in research on hair loss, bone formation, gastric ulcer healing, and dermal wound healing .

HY-136403

TIS108	Phytohormone	Others
TIS108 is a triazole-type strigolactone biosynthesis inhibitor. TIS108 inhibits Arabidopsis embryogenesis and root hair growth, and promotes shoot branching. TIS108 can also increase the gibberellin content in Gastrodia elata. TIS108 can be used in the research of plant growth and development as well as plant responses to the environment .

HY-B0112R

Minoxidil (Standard)	Potassium Channel Endogenous Metabolite	Cardiovascular Disease Cancer
Minoxidil (Standard) is the analytical standard of Minoxidil. This product is intended for research and analytical applications. Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM .

HY-125283

IM176OUT05	Mitochondrial Metabolism	Metabolic Disease
IM176OUT05 is a high solubility biguanide. IM176OUT05 activates stem cell metabolism, promotes hair regrowth and increases stemness induction and maintenance during the pluripotent stem cell generation process. IM176OUT0 inhibits mitochondrial electron transport chain (ETC) activity with an IC₅₀ of 3.2 μM .

HY-161618

MJ04	JAK EGFR PI3K IGF-1R GSK-3	Inflammation/Immunology Endocrinology
MJ04 is a selective inhibitor for Janus Kinase 3 (JAK 3) with an IC₅₀ of 2.03 nM. MJ04 inhibits T cell differentation and inhibits the proinfammatory cytokines in Lipopolysaccharides (HY-D1056)‑induced macrophages. MJ04 exhibits good pharmacokinetic characters in mice, promotes hair growth in DHT-induced androgenetic alopecia (AGA) in athymic mice model, without significant toxicity (LD₅₀ >2 g/kg) .

HY-23196S

Minoxidil-d10	Potassium Channel	Neurological Disease
Minoxidil-d₁₀ (U10858-d10) is the deuterium labeled Minoxidil. Minoxidil (U10858) is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth. Minoxidil is also a potent inhibitor of soybean lipoxygenaseare with an IC50 of 20 μM[1][2][3].

HY-160547

PROTAC AR Degrader-5	PROTACs Androgen Receptor	Metabolic Disease
PROTAC AR Degrader-5 (compound A46) is a potent AR PROTACs degrader with an IC₅₀ value of 49 nM. PROTAC AR Degrader-5 inhibits sebaceous plaque and induces hair regeneration (Pink: ligand for target protein (HY-169967); black: linker (HY-169966); Blue: E3 ligase ligand (HY-125845)) .

HY-108952

17,17-(Ethylenedioxy)androst-4-en-3-one	5 alpha Reductase	Endocrinology
17,17-(Ethylenedioxy)androst-4-en-3-one (4- androstene- 3, 17- dione- 17- cyclic ethylene ketal) is an effective ingredient in cosmetics, which can be used for acne and promote hair growth research. 17,17-(Ethylenedioxy)androst-4-en-3-one can inhibit the reductase activity and inhibit the bond of a receptor protein and 5α-DHT .

HY-N2071

Cedrol 1 Publications Verification (+)-Cedrol; α-Cedrol	Cytochrome P450 Fungal Apoptosis Caspase Platelet-activating Factor Receptor (PAFR)	Infection Neurological Disease Inflammation/Immunology Cancer
Cedrol is a potent competitive inhibitor of cytochrome P-450(CYP) enzyme. Cedrol plays an anticancer role by inducing cell cycle arrest and Caspase-dependent apoptosis. Cedrol acts as a neutrophil agonist that can desensitize cells to subsequent stimulation of N-formyl peptides. Cedrol prevents neuropathic pain caused by chronic contractile injury by inhibiting oxidative stress and inflammation. In addition, Cedrol has antibacterial, hair loss prevention and anti-anxiety properties .

HY-N2071R

Cedrol (Standard)	Cytochrome P450 Fungal Apoptosis Caspase	Infection Neurological Disease Inflammation/Immunology Cancer
Cedrol (Standard) is the analytical standard of Cedrol. This product is intended for research and analytical applications. Cedrol is a potent competitive inhibitor of cytochrome P-450(CYP) enzyme. Cedrol plays an anticancer role by inducing cell cycle arrest and Caspase-dependent apoptosis. Cedrol acts as a neutrophil agonist that can desensitize cells to subsequent stimulation of N-formyl peptides. Cedrol prevents neuropathic pain caused by chronic contractile injury by inhibiting oxidative stress and inflammation. In addition, Cedrol has antibacterial, hair loss prevention and anti-anxiety properties.

HY-B1090

Cinnarizine	Calcium Channel Histamine Receptor	Cardiovascular Disease Endocrinology
Cinnarizine is an orally active, effective and selective inhibitor of L-type calcium channel Cav1.3 with an IC₅₀ of 1.5 μM (in vestibular hair cells). Cinnarizine can cross the blood-brain barrier and regulate calcium homeostasis and dopamine neurotransmission. Cinnarizine inhibits the influx of calcium ions into smooth muscle cells by blocking L-type calcium channels, thereby relaxing vascular smooth muscle, improving cerebral circulation and reducing blood viscosity, while antagonizing dopamine receptors. Cinnarizine can be used in the study of vestibular vertigo, Meniere's disease and cerebrovascular diseases .

Cat. No.	Product Name	Type