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Herbicidal agent

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By Targets:	Bacterial (1) Fungal (1) Herbicide (17) Parasite (1) Phytohormone (1) Protoporphyrinogen IX oxidase (2) Reactive Oxygen Species (ROS) (2) Transketolase (2)
By Research Areas:	Infection (3) Inflammation/Immunology (1)

Inhibitors & Agonists

Natural
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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-169168

Herbicidal agent 6	Transketolase	Others
Herbicidal agent 6 (D15) is a Transketolase (TKL) inhibitor with herbicidal activity .

HY-148429

Antimalarial agent 17	Parasite	Others
Antimalarial agent 17 is an antimalarial agent, also acts as a herbicide. Antimalarial agent 17 is photosystem II inhibitor, shows post-emergence herbicidal activity equal to commercial herbicides .

HY-163311

Transketolase-IN-6	Transketolase Herbicide	Others
Transketolase-IN-6 is a potent transketolase inhibitor and a herbicide. Transketolase-IN-6 inhibits root growth of Digitaria sanguinalis, Amaranthus retroflexus, and Setaria viridis. Transketolase-IN-6 shows low phytotoxicity to wheat, maize, soybean, and cotton. Transketolase-IN-6 can be used for the research of herbicidal agent development .

HY-175736

Herbicidal agent 11	Herbicide	Others
Herbicidal agent 11 (Compound 8a) is a herbicidal agent. Herbicidal agent 11 has significant postemergence herbicidal activities against the monocotyledonous weed Echinochloa crusgalli with inhibition of potent root and stem growth and has a good crop selectivity against wheat, maize, and oilseed rape. Herbicidal agent 11 also has effective inhibitory effects on Digitaria sanguinalis, Eclipta prostrate and Eleusine indica. Herbicidal agent 11 can be used for the development of herbicides .

HY-158163

Herbicidal agent 4	Herbicide	Inflammation/Immunology
Herbicidal agent 4 (compound V-2) is an auxinic herbicidal agent. Herbicidal agent 4 may also be an immune activator while upregulating the defense genes and increasing content of jasmonic acid .

HY-163298

Herbicidal agent 2	Protoporphyrinogen IX oxidase	Others
Herbicidal agent 2 (compound 8d), a herbicide, is a protoporphyrinogen oxidase (PPO) inhibitor. Herbicidal agent 2 exhibits herbicidal activities against broadleaf and monocotyledon weeds .

HY-168496

Herbicidal agent 8	Herbicide Phytohormone	Others
Herbicidal agent 8 (Compound 9w) targets the auxin indole-3-acetic acid (IAA, IC₅₀=4.389 μM), disrupting the physiological activities of plant cells and eventually causing plant death. Herbicidal agent 8 exhibits herbicidal activity against broadleaf weeds and grass weeds .

HY-185138

Herbicidal agent 14	Herbicide	Others
Herbicidal agent 14 (compound 17) is a herbicide with an excellent herbicidal effect when controlling broadleaf weeds before/after emergence .

HY-179280

Herbicidal agent 13	Herbicide Reactive Oxygen Species (ROS)	Others
Herbicidal agent 13 (Compound II-13) is a *herbicidal* agent. Herbicidal agent 13 retains the dual-target binding capabilities for PDS and ZDS, with K_d values of 71.8 μM and 0.586 mM against SynPDS and AtZDS, respectively. Herbicidal agent 13 increases ROS. Herbicidal agent 13 exhibits postemergence herbicidal activity against dicotyledonous weeds and monocotyledonous weed POLFU .

HY-173429

Herbicidal agent 10	Herbicide	Infection
Herbicidal agent 10 (compound 3s) is a potent herbicidal agent. Herbicidal agent 10 inhibits SvEPSPS with an IC₅₀ of 7.8 μM .

HY-157025

Herbicidal agent 1	Herbicide	Others
Herbicidal agent 1 （(S)-6q）is a herbicidal agent with superior activity than its racemate .

HY-N15426

Herbicidal agent 9	Herbicide	Others
Herbicidal Agent 9 (Compound 5) is a herbicidal derivative of 23-spirocholestane. In combination with Compound 6, Herbicidal Agent 9 inhibits Arabidopsis root growth, exhibiting an EC₅₀ of 6.89 μM .

HY-185451

Herbicidal agent 15	Herbicide	Others
Herbicidal agent 15 is a uracilpyridine herbicide. Herbicidal agent 15 controls harmful plants and acts on plants, their seeds, and their habitat to manage unwanted vegetation .

HY-158112

Herbicidal agent 3	Herbicide	Others
Herbicidal agent 3 (compound 7A) shows herbicidal activity against Digitaria sanguinalis and Amaranthus retroflexus at a dosage of 90 g ai/ha. Herbicidal agent 3 inhibites Setaria viridis TKL (SvTKL) enzyme activity, with the IC₅₀ of 0.740 mg/L .

HY-173026

Herbicidal agent 7	Herbicide	Others
Herbicidal agent 7 (Compound 15c) is the inhibitor for protoporphyrinogen IX oxidase (PPO). Herbicidal agent 7 blocks the plant pigment synthesis, exhibiting herbicidal activity against broadleaf weeds (such as Z. elegans and A. theophrasti) and grass weeds (such as S. glauca and E. crusgalli) .

HY-183559

Herbicidal agent 16	Protoporphyrinogen IX oxidase Herbicide	Others
Herbicidal agent 16 is a herbicide and Protoporphyrinogen IX oxidase (PPO) inhibitor with an IC₅₀ of 15.1 nM and K_d of 24.89 nM. Herbicidal agent 16 can be used for research on herbicides .

HY-175844

Herbicidal agent 12	Herbicide	Others
Herbicidal agent 12 (compound 6q) is a potent pyrimidinedione herbicide with strong herbicidal activity against broadleaf weeds .

HY-163910

Herbicidal agent 5	Herbicide	Others
Herbicidal agent 5 (compound B5) is a herbicide that acts on Photosynthetic System II (PS II) .

HY-174388

Antifungal agent 134	Fungal Herbicide Reactive Oxygen Species (ROS)	Infection
Antifungal agent 134 (Compound B13) is an antifungal agent with EC₅₀s of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL for Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata, respectively. Antifungal agent 134 can disrupt the cell membrane and mitochondria of the hyphae, leading to significant ROS accumulation. Antifungal agent 134 also has significant herbicidal activities against field weeds, such as Amaranthus retroflexus L and Abutilon theophrasti Medicus. Antifungal agent 134 can be used for crop diseases and field weeds research .

HY-170401

Antibacterial agent 260	Bacterial Herbicide	Infection
Antibacterial agent 260 (Compound 4r) exhibits board-spectrum antibacterial activity, inhibits P. aeruginosa and S. aureus with MIC of 0.0076 μM. Antibacterial agent 260 acts as a herbicidal agent, that inhibits the root- and stem-growth of Raphanus sativus L. (radish seed) .

Herbicidal agent 9	Structural Classification Microorganisms Ypsilandra thibetica Franch. Plants Melanthiaceae Steroids Source Classification	Herbicide
Herbicidal Agent 9 (Compound 5) is a herbicidal derivative of 23-spirocholestane. In combination with Compound 6, Herbicidal Agent 9 inhibits Arabidopsis root growth, exhibiting an EC₅₀ of 6.89 μM .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Herbicidal agent

Inhibitors & Agonists

NaturalProducts

Natural
Products