Herbicidal agent 16

Herbicidal agent 16 (Compound S1) (4.69-150 g a.i./ha; 7 days post-treatment) provides 80-100% postemergence control of Echinochloa crus-galli, Digitaria sanguinalis, Setaria viridis, Amaranthus retroflexus, Abutilon theophrasti, and Veronica polita at concentrations as low as 4.69 g a.i./ha^[1].
Herbicidal agent 16 (37.5-150 g a.i./ha) exhibits broad-spectrum herbicidal activity, providing 80-100% control of 24 diverse weed species at 150 g a.i./ha^[1].
Herbicidal agent 16 (37.5-150 g a.i./ha; 14 days post-treatment) is safe for rice and wheat at dosages up to 150 g a.i./ha, causing only 0-20% phytotoxicity, while exhibiting higher phytotoxicity to corn, soybean, cotton, and peanut^[1].
Herbicidal agent 16 potently inhibits plant PPO enzyme activity with an IC₅₀ of 15.1 nM^[1].
Herbicidal agent 16 (1.57-50.00 nM) binds to purified PPO protein with high affinity, exhibiting a K_d of 24.89 nM^[1].
Herbicidal agent 16 (150 g a.i./ha; 3-24 h post-treatment) rapidly and significantly downregulates relative PPO gene expression in Nicotiana benthamiana leaves, with suppression observed as early as 3 h post-treatment^[1].
Herbicidal agent 16 binds to the active site of PPO enzyme (PDB ID: 1SEZ) via multiple stabilizing interactions, including π-π stacking, halogen bonds, hydrogen bonds, and hydrophobic interactions, contributing to its high inhibitory potency^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.