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Results for "

MAPT

" in MedChemExpress (MCE) Product Catalog:

7

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1

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1

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1

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9

Recombinant Proteins

4

Antibodies

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Cat. No. Compare Product Name Species Source
  • HY-P70589
    Tau-F/MAPT Protein, Human

    DDPAC; FLJ31424; FTDP-17; G protein beta1/gamma2 subunit-interacting factor 1; MAPT; MGC138549; microtubule-associated protein tau; MSTD; MSTDMAPTL; MTBT1; MTBT1Neurofibrillary tangle protein; MTBT2; Neurofibrillary tangle protein; PHF-tau; PPND; Tau; TAUPaired helical filament-tau

    		 Human E. coli
    Microtubule-associated protein tau is a microtubule-associated protein found in large numbers in neurons of the central nervous system (CNS). MAPT promotes microtubule assembly and stability and may be involved in the establishment and maintenance of neuronal polarity. Overexpression of MAPT is associated with a poor prognosis of prostate cancer. MAPT has been linked to neurological disorders such as Alzheimer's and Parkinson's disease. Tau-F/MAPT Protein, Human is the recombinant human-derived Tau-F/MAPT protein, expressed by E. coli , with tag free. The total length of Tau-F/MAPT Protein, Human is 441 a.a., with molecular weight of ~60.0 kDa.
  • HY-P700423
    Tau/MAPT Protein, Macaca mulatta (HEK293, His)

    MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; microtubule-associated protein tau; microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1

    		 Rhesus Macaque HEK293
    Tau/MAPT Protein crucially promotes microtubule assembly and stability, essential for neuronal polarity. Structurally, its C-terminus binds axonal microtubules, and the N-terminus engages neural plasma membrane components, suggesting a role as a linker protein connecting microtubules to the plasma membrane. Tau's localization dictates axonal polarity, particularly near the centrosome. Short isoforms offer cytoskeletal plasticity, while longer isoforms stabilize microtubules. Tau interacts with proteins like MARK1, MARK2, SQSTM1, and LRP1, revealing its multifaceted role in cellular processes. Tau/MAPT Protein, Macaca mulatta (HEK293, His) is the recombinant Rhesus Macaque-derived Tau/MAPT protein, expressed by HEK293, with N-10*His labeled tag. The total length of Tau/MAPT Protein, Macaca mulatta (HEK293, His) is 458 a.a., with molecular weight of 50.6 kDa.
  • HY-P700421
    Tau-F/MAPT Protein, Human (HEK293, His)

    MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; microtubule-associated protein tau; microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1

    		 Human HEK293
    Microtubule-associated protein tau is a microtubule-associated protein found in large numbers in neurons of the central nervous system (CNS). MAPT promotes microtubule assembly and stability and may be involved in the establishment and maintenance of neuronal polarity. Overexpression of MAPT is associated with a poor prognosis of prostate cancer. MAPT has been linked to neurological disorders such as Alzheimer's and Parkinson's disease. Tau-F/MAPT Protein, Human (HEK293, His) is the recombinant human-derived Tau-F/MAPT protein, expressed by HEK293 , with N-10*His labeled tag. The total length of Tau-F/MAPT Protein, Human (HEK293, His) is 441 a.a., with molecular weight of 49.5 kDa.
  • HY-P700424
    Tau/MAPT Protein, Rat (HEK293, His)

    MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; microtubule-associated protein tau; microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1

    		 Rat HEK293
    Microtubule-associated protein tau (MAPT) critically promotes microtubule assembly and stability, influencing neuronal polarity by acting as a vital linker protein. Its dual role involves the C-terminus binding axonal microtubules and the N-terminus engaging neural plasma membrane components. Tau's cellular localization, especially near the centrosome, determines axonal polarity. Short tau isoforms offer cytoskeletal plasticity, while longer isoforms likely stabilize microtubules. MAPT engages with various proteins, including MARK1, MARK2, SQSTM1, LRP1, showcasing its multifaceted role in cellular processes. The interaction with LRP1, leading to endocytosis, highlights the intricate regulatory mechanisms governing tau's functional versatility. Tau/MAPT Protein, Rat (HEK293, His) is the recombinant rat-derived Tau/MAPT protein, expressed by HEK293, with N-10*His labeled tag. The total length of Tau/MAPT Protein, Rat (HEK293, His) is 751 a.a., with molecular weight of 81.2 kDa.
  • HY-P700422
    Tau/MAPT Protein, Mouse (HEK293, His)

    MAPT; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17; microtubule-associated protein tau; microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1

    		 Mouse HEK293
    Microtubule-associated protein tau (MAPT) plays a pivotal role in promoting microtubule assembly and stability, indicating its potential contribution to neuronal polarity establishment. The C-terminus binds to axonal microtubules, while the N-terminus interacts with neural plasma membrane components, serving as a crucial linker protein between these structures. Tau's localization within the neuronal cell, particularly in the centrosome-defined domain, dictates axonal polarity. Short MAPT isoforms enhance cytoskeletal plasticity, while longer isoforms stabilize it. MAPT engages in diverse interactions with proteins like MARK1, MARK2, MARK3, MARK4, SQSTM1, PSMC2, FKBP4, CSNK1D, SGK1, EPM2A, PIN1, LRRK2, and LRP1, participating in processes from ubiquitination to dephosphorylation and endocytosis, underscoring its multifaceted role in cellular dynamics. Tau/MAPT Protein, Mouse (HEK293, His) is the recombinant mouse-derived Tau/MAPT protein, expressed by HEK293, with N-10*His labeled tag. The total length of Tau/MAPT Protein, Mouse (HEK293, His) is 732 a.a., with molecular weight of 78.9 kDa.
  • HY-P71102
    Tau-D/0N4R Protein, Human (133a.a, His)

    Microtubule-Associated Protein Tau; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; MAPT; MAPTL; MTBT1; TAU

    		 Human E. coli
    Microtubule-associated protein tau is a microtubule-associated protein found in large numbers in neurons of the central nervous system (CNS). MAPT promotes microtubule assembly and stability and may be involved in the establishment and maintenance of neuronal polarity. Overexpression of MAPT is associated with a poor prognosis of prostate cancer. MAPT has been linked to neurological disorders such as Alzheimer's and Parkinson's disease. Tau-D/0N4R Protein, Human (133a.a, His) is the recombinant human-derived Tau-D/0N4R protein, expressed by E. coli , with C-6*His labeled tag. The total length of Tau-D/0N4R Protein, Human (133a.a, His) is 133 a.a., with molecular weight of ~16.0 kDa.
  • HY-P71753
    Microtubule-associated protein tau Protein, Rat (P.pastoris, His)

    MAPT; Mtapt; Tau; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau

    		 Rat P. pastoris
    Microtubule-associated protein tau (MAPT) critically promotes microtubule assembly and stability, influencing neuronal polarity by acting as an important junction protein. Its dual role involves C-terminal binding to axonal microtubules and N-terminal binding to neuroplasmic membrane components. Microtubule-associated protein tau Protein, Rat (P.pastoris, His) is the recombinant rat-derived Microtubule-associated protein tau protein, expressed by P. pastoris , with N-His labeled tag. The total length of Microtubule-associated protein tau Protein, Rat (P.pastoris, His) is 751 a.a., with molecular weight of ~80.4 kDa.
  • HY-P71752
    Microtubule-associated protein tau Protein, Mouse (P.pastoris, His)

    MAPT; Mtapt; Tau; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau

    		 Mouse P. pastoris
    Microtubule-associated protein tau (MAPT) plays a key role in promoting microtubule assembly and stability, suggesting its potential contribution to the establishment of neuronal polarity. The C terminus binds to axonal microtubules, whereas the N terminus interacts with neuroplasmic membrane components, serving as a key linker protein between these structures. Microtubule-associated protein tau Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Microtubule-associated protein tau protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Microtubule-associated protein tau Protein, Mouse (P.pastoris, His) is 732 a.a., with molecular weight of ~78.1 kDa.
  • HY-P73618
    Tau/0N3R Protein, Human (351a.a, His)

    MAPT; Mtapt; Tau; Microtubule-associated protein tau; PHF-tau

    		 Human E. coli
    Tau/0N3R protein is encoded by the Tau/0N3R gene and undergoes regulated alternative splicing to produce different mRNA species. Its expression varies in the nervous system according to the maturation and type of neurons. Tau/0N3R Protein, Human (351a.a, His) is the recombinant human-derived Tau/0N3R protein, expressed by E. coli , with N-His labeled tag. The total length of Tau/0N3R Protein, Human (351a.a, His) is 351 a.a., with molecular weight of 40-50 kDa.

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