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Results for "

S100A8

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

8

Recombinant Proteins

2

Isotope-Labeled Compounds

1

Antibodies

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  • HY-P73671
    S100A8 Protein, Mouse (sf9, His)

    Protein S100-A8; Calgranulin-A; MRP-8; S100A8; Caga

    		 Mouse Sf9 insect cells
    S100A8 protein plays crucial roles in the immune system and inflammation. It activates NADPH-oxidase, generating reactive oxygen species in immune cells. Additionally, S100A8 facilitates the assembly of the NADPH-oxidase enzyme complex at the cell membrane and transfers the essential cofactor arachidonic acid to the complex. S100A8 Protein, Mouse (sf9, His) is the recombinant mouse-derived S100A8 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of S100A8 Protein, Mouse (sf9, His) is 89 a.a., with molecular weight of ~11.7 kDa.
  • HY-P70531
    S100A8 Protein, Human (C-His)

    Protein S100-A8; S100A8; Calgranulin-A; Cystic fibrosis antigen; Leukocyte L1 complex light chain; MRP-8

    		 Human E. coli
    S100A8 consists of calcium and zinc bound S100A8, which plays a critical regulatory role in inflammation and immune responses. As calprotectin, it contributes to leukocyte function, regulates the cytoskeleton, and activates intracellular NADPH oxidase. S100A8 Protein, Human (C-His) is the recombinant human-derived S100A8 protein, expressed by E. coli , with C-6*His labeled tag. The total length of S100A8 Protein, Human (C-His) is 93 a.a., with molecular weight of ~13.0 kDa.
  • HY-P70531A
    S100A8 Protein, Human (N-His)

    Protein S100-A8; S100A8; Calgranulin-A; Cystic fibrosis antigen; Leukocyte L1 complex light chain; MRP-8

    		 Human E. coli
    S100A8 consists of calcium and zinc bound S100A8, which plays a critical regulatory role in inflammation and immune responses. As calprotectin, it contributes to leukocyte function, regulates the cytoskeleton, and activates intracellular NADPH oxidase. S100A8 Protein, Human (N-His) is the recombinant human-derived S100A8 protein, expressed by E. coli , with N-6*His labeled tag. The total length of S100A8 Protein, Human (N-His) is 93 a.a., with molecular weight of ~12 kDa.
  • HY-P76586
    S100A8 Protein, Human (sf9, His)

    Protein S100-A8; S100A8; Calgranulin-A; Cystic fibrosis antigen; Leukocyte L1 complex light chain; MRP-8

    		 Human Sf9 insect cells
    S100A8 consists of calcium and zinc bound S100A8, which plays a critical regulatory role in inflammation and immune responses. As calprotectin, it contributes to leukocyte function, regulates the cytoskeleton, and activates intracellular NADPH oxidase. S100A8 Protein, Human (sf9, His) is the recombinant human-derived S100A8 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of S100A8 Protein, Human (sf9, His) is 93 a.a., with molecular weight of ~14.6 kDa.
  • HY-P71275
    S100A8 Protein, Rat (His)
    2 Publications Verification

    Protein S100-A8; S100A8; Calgranulin-A; Chemotactic cytokine CP-10; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; MRP-8; Pro-inflammatory S100 cytokine; S100 calcium-binding protein A8; Caga; Mrp8

    		 Rat E. coli
    S100A8 protein functions as a danger signal in inflammation, activating innate immune cells by binding to receptors like Toll-like receptor 4 (TLR4) and receptor for advanced glycation endproducts (AGER). This triggers signaling pathways that enhance the pro-inflammatory response. S100A8 Protein, Rat (His) is the recombinant rat-derived S100A8 protein, expressed by E. coli , with C-6*His labeled tag. The total length of S100A8 Protein, Rat (His) is 89 a.a., with molecular weight of ~13.0 kDa.
  • HY-P71779
    S100A8 Protein, Mouse (P.pastoris, His)

    Caga; MRP-8

    		 Mouse P. pastoris
    S100A8 protein plays crucial roles in the immune system and inflammation. It activates NADPH-oxidase, generating reactive oxygen species in immune cells. Additionally, S100A8 facilitates the assembly of the NADPH-oxidase enzyme complex at the cell membrane and transfers the essential cofactor arachidonic acid to the complex. S100A8 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived S100A8 protein, expressed by P. pastoris , with N-His labeled tag. The total length of S100A8 Protein, Mouse (P.pastoris, His) is 88 a.a., with molecular weight of ~12.2 kDa.
  • HY-P73670
    S100A8-S100A9 Heterodimer Protein, Human (sf9, Flag-His)

    CAGA; CAGB; CFAG; MRP14; MRP8&S100A9 Protein; S100A8; S100A9

    		 Human Sf9 insect cells
    The S100A8, composed of calcium- and zinc-binding S100A8, crucially regulates inflammation and immune responses. As calprotectin, it aids leukocyte functions, modulates cytoskeleton, and activates NADPH-oxidase intracellularly. Extracellularly, it displays pro-inflammatory, antimicrobial, and apoptosis-inducing activities, acting as a DAMP molecule that stimulates innate immune cells through TLR4 and AGER. With antimicrobial effects, it regulates neutrophils, induces cell death, and prevents tissue damage. Notably, it amplifies inflammation in autoimmunity and cancer, potentially influencing aberrant neutrophil expansion in microbial infections like SARS-CoV-2. S100A8-S100A9 Heterodimer Protein, Human (sf9, Flag-His) is a recombinant protein dimer complex containing human-derived S100A8-S100A9 Heterodimer protein, expressed by Sf9 insect cells, with C-His, C-Flag labeled tag. S100A8-S100A9 Heterodimer Protein, Human (sf9, Flag-His), has molecular weight of ~12.2 & 14.2 kDa, respectively.
  • HY-P71076
    S100A8-S100A9 Heterodimer Protein, Human (His)
    1 Publications Verification

    S100A8/S100A9 Heterodimer

    		 Human E. coli
    S100A8, binding to calcium and zinc, crucially regulates inflammation and immune responses. As calprotectin, it aids leukocyte functions, modulates cytoskeleton, and activates NADPH-oxidase intracellularly. Extracellularly, it displays pro-inflammatory, antimicrobial, and apoptosis-inducing activities, acting as a DAMP molecule that stimulates innate immune cells through TLR4 and AGER. With antimicrobial effects, it regulates neutrophils, induces cell death, and prevents tissue damage. Notably, it amplifies inflammation in autoimmunity and cancer, potentially influencing aberrant neutrophil expansion in microbial infections like SARS-CoV-2. S100A8-S100A9 Heterodimer Protein, Human (His) is a recombinant protein dimer complex containing human-derived S100A8-S100A9 Heterodimer protein, expressed by E. coli, with C-6*His labeled tag. S100A8-S100A9 Heterodimer Protein, Human (His), has molecular weight of 13 & 15 kDa, respectively.

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