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Results for "

SELP

" in MedChemExpress (MCE) Product Catalog:

1

Inhibitors & Agonists

11

Recombinant Proteins

2

Antibodies

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Cat. No. Compare Product Name Species Source
  • HY-P78201
    P-Selectin Protein, Human (Biotinylated, HEK293, His-Avi)

    FLJ45155; GMP140; GRMP; PADGEM; PSEL; P-Selectin; SELP; CD62P; CD62; LECAM3

    		 Human HEK293
    P-selectin, a Ca(2+)-dependent receptor on myeloid cells, crucially binds to sialyl-Lewis X on neutrophils and monocytes, facilitating the interaction of activated endothelial cells or platelets with leukocytes. This engagement, primarily with SELPLG/PSGL1 and PODXL2, is vital for the rapid rolling of leukocytes during early inflammation. P-selectin's interactions with SNX17 further mediate neutrophil adhesion and rolling, dependent on the sialyl-Lewis X epitope and specific tyrosine sulfation on SELPLG. P-Selectin Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived P-Selectin protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of P-Selectin Protein, Human (Biotinylated, HEK293, His-Avi) is 730 a.a., with molecular weight of 115-140 kDa.
  • HY-P78511
    P-Selectin Protein, Human (HEK293, His-Avi)

    FLJ45155; GMP140; GRMP; PADGEM; PSEL; P-Selectin; SELP; CD62P; CD62; LECAM3

    		 Human HEK293
  • HY-P78349
    P-Selectin Protein, Mouse (HEK293, His)

    FLJ45155; GMP140; GRMP; PADGEM; PSEL; P-Selectin; SELP; CD62P; CD62; LECAM3

    		 Mouse HEK293
    P-selectin, a Ca(2+)-dependent receptor on myeloid cells, binds specifically to carbohydrates on neutrophils and monocytes. It mediates interaction between activated endothelial cells or platelets and leukocytes through recognition of sialyl-Lewis X. P-selectin facilitates leukocyte rolling over vascular surfaces during inflammation by interacting with SELPLG and SNX17. It also promotes neutrophil adhesion and leukocyte rolling through interactions with SELPLG/PSGL1 and PODXL2, requiring sialyl-Lewis X and tyrosine sulfation on SELPLG. P-Selectin Protein, Mouse (HEK293, His) is the recombinant mouse-derived P-Selectin protein, expressed by HEK293 , with C-His labeled tag. The total length of P-Selectin Protein, Mouse (HEK293, His) is 668 a.a., with molecular weight of 110-130 kDa.
  • HY-P73688
    P-Selectin Protein, Rhesus Macaque (HEK293, Fc)

    P-selectin; GMP-140; LECAM3; PADGEM; CD62P; SELP

    		 Rhesus Macaque HEK293
    P-Selectin Protein, Rhesus Macaque (HEK293, His) is a member of the selectin family of cell adhesion molecules. P-selectin (CD62P) has an N-terminal lectin domain, an epidermal growth factor motif, (generally) nine regulatory protein repeats, a transmembrane section and a short intracytoplasmic tail. P-selectin mediates leukocyte rolling on stimulated endothelial cells and heterotypic aggregation of activated platelets onto leukocytes. P-selectin mediates heterotypic aggregation of activated platelets to cancer cells and adhesion of cancer cells to stimulated endothelial cells. P-selectin glycoprotein ligand-1 (PSGL-1) is a major ligand for P-selectin. P-Selectin Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived P-Selectin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of P-Selectin Protein, Rhesus Macaque (HEK293, Fc) is 730 a.a., with molecular weight of ~106.8 kDa.
  • HY-P73687
    P-Selectin Protein, Rhesus Macaque (HEK293, His)

    P-selectin; GMP-140; LECAM3; PADGEM; CD62P; SELP

    		 Rhesus Macaque HEK293
    P-Selectin Protein, Rhesus Macaque (HEK293, His) is a member of the selectin family of cell adhesion molecules. P-selectin (CD62P) has an N-terminal lectin domain, an epidermal growth factor motif, (generally) nine regulatory protein repeats, a transmembrane section and a short intracytoplasmic tail. P-selectin mediates leukocyte rolling on stimulated endothelial cells and heterotypic aggregation of activated platelets onto leukocytes. P-selectin mediates heterotypic aggregation of activated platelets to cancer cells and adhesion of cancer cells to stimulated endothelial cells. P-selectin glycoprotein ligand-1 (PSGL-1) is a major ligand for P-selectin. P-Selectin Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived P-Selectin protein, expressed by HEK293 , with C-His labeled tag. The total length of P-Selectin Protein, Rhesus Macaque (HEK293, His) is 730 a.a., with molecular weight of ~81.2 kDa.
  • HY-P73690
    P-Selectin Protein, Human (HEK293, Fc)

    P-selectin; GMP-140; LECAM3; PADGEM; CD62P; SELP

    		 Human HEK293
    P-selectin, a Ca(2+)-dependent receptor on myeloid cells, crucially binds to sialyl-Lewis X on neutrophils and monocytes, facilitating the interaction of activated endothelial cells or platelets with leukocytes. This engagement, primarily with SELPLG/PSGL1 and PODXL2, is vital for the rapid rolling of leukocytes during early inflammation. P-selectin's interactions with SNX17 further mediate neutrophil adhesion and rolling, dependent on the sialyl-Lewis X epitope and specific tyrosine sulfation on SELPLG. P-Selectin Protein, Human (HEK293, Fc) is the recombinant human-derived P-Selectin protein, expressed by HEK293, with C-hFc labeled tag. The total length of P-Selectin Protein, Human (HEK293, Fc) is 730 a.a., with molecular weight of 130-150 kDa.
  • HY-P73689
    P-Selectin Protein, Rat (HEK293, His)

    P-selectin; GMP-140; LECAM3; PADGEM; CD62P; SELP

    		 Rat HEK293
    P-Selectin, a Ca(2+)-dependent receptor on myeloid cells, binds to neutrophils and monocytes via carbohydrates. It interacts with SELPLG to enable rapid leukocyte rolling over vascular surfaces in early inflammation. P-Selectin also interacts with SNX17 and promotes neutrophil adhesion and rolling, requiring SELPLG's sialyl-Lewis X and tyrosine sulfation. P-Selectin Protein, Rat (HEK293, His) is the recombinant rat-derived P-Selectin protein, expressed by HEK293 , with C-His labeled tag. The total length of P-Selectin Protein, Rat (HEK293, His) is 659 a.a., with molecular weight of ~115 kDa.
  • HY-P73385
    P-Selectin Protein, Rat (HEK293, Fc)

    P-selectin; GMP-140; LECAM3; PADGEM; CD62P; SELP

    		 Rat HEK293
    P-Selectin, a Ca(2+)-dependent receptor on myeloid cells, binds to neutrophils and monocytes via carbohydrates. It interacts with SELPLG to enable rapid leukocyte rolling over vascular surfaces in early inflammation. P-Selectin also interacts with SNX17 and promotes neutrophil adhesion and rolling, requiring SELPLG's sialyl-Lewis X and tyrosine sulfation. P-Selectin Protein, Rat (HEK293, Fc) is the recombinant rat-derived P-Selectin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of P-Selectin Protein, Rat (HEK293, Fc) is 659 a.a., with molecular weight of ~98.7 kDa.
  • HY-P73383
    P-Selectin Protein, Mouse (HEK293, Fc)

    P-selectin; GMP-140; LECAM3; PADGEM; CD62P; SELP

    		 Mouse HEK293
    P-selectin is a Ca(2+)-dependent receptor on myeloid cells that specifically binds to carbohydrates on neutrophils and monocytes. It mediates interactions between activated endothelial cells or platelets and leukocytes by recognizing sialic acid-Lewis X. P-Selectin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived P-Selectin protein, expressed by HEK293 , with C-hFc labeled tag. The total length of P-Selectin Protein, Mouse (HEK293, Fc) is 668 a.a., with molecular weight of ~135 kDa.
  • HY-P700815
    CD162/PSGL-1 Protein, Cynomolgus (HEK293, His)

    CLA; PSGL-1; PSGL1; CD162; SELPLG; Selectin P ligand; SELP1; SELPl

    		 Cynomolgus HEK293
    As a member of the selectin family, CD162/PSGL-1 is mainly expressed in some immune or inflammatory cells. CD162/PSGL-1 deficiency affects myeloid differentiation and lymphocyte maturation and therefore has important implications for cell differentiation. CD162/PSGL-1 can be used as an immune checkpoint modulator and may be a new target for cancer therapy. CD162/PSGL-1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD162/PSGL-1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD162/PSGL-1 Protein, Cynomolgus (HEK293, His) is 323 a.a., with molecular weight of 72-82 kDa.
  • HY-P700816
    CD162/PSGL-1 Protein, Mouse (266a.a, HEK293, His)

    CLA; PSGL-1; PSGL1; CD162; SELPLG; Selectin P ligand; SELP1; SELPl

    		 Mouse HEK293
    CD162/PSGL-1 protein, an SLe(x)-type proteoglycan, facilitates early inflammation stages by mediating rapid leukocyte rolling through high-affinity interactions with E- and P-selectins. CD162 forms homodimers linked by disulfide bonds, interacting with selectins through lectin/EGF domains. For high-affinity P-selectin binding, sialyl Lewis X glycan modification and tyrosine sulfation, likely on Tyr-54, are required. Dimerization seems dispensable. CD162 also interacts with SNX20, mediating SYK activation, and with MSN and SYK, contributing to downstream signaling events. Its engagement with HAVCR1 reveals diverse cellular interactions. CD162/PSGL-1 Protein, Mouse (266a.a, HEK293, His) is the recombinant mouse-derived CD162/PSGL-1 protein, expressed by HEK293, with C-His labeled tag. The total length of CD162/PSGL-1 Protein, Mouse (266a.a, HEK293, His) is 266 a.a., with molecular weight of 68-108 kDa.

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