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Solasodine

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By Targets:	Apoptosis (5) Drug Intermediate (1) E1/E2/E3 Enzyme (3) Fungal (3) MDM-2/p53 (3) P-glycoprotein (2) Reference Standards (3)
By Research Areas:	Cancer (5) Cardiovascular Disease (3) Infection (3) Inflammation/Immunology (3) Neurological Disease (3)

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Natural
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Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-N0069

Solamargine 10+ Cited Publications Solamargin; δ-Solanigrine	P-glycoprotein Apoptosis	Cancer
Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. Solamargine significantly inhibits migration and invasion of HepG2 cells by down-regulating MMP-2 and MMP-9 expression and activity .

HY-N0068

*Solasodine* 5 Publications Verification Purapuridine; Solancarpidine; Solasodin	MDM-2/p53 Fungal E1/E2/E3 Enzyme Apoptosis	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Solasodine (Purapuridine) is a steroidal alkaloid that occurs in plants of the Solanaceae family. Solasodine induces apoptosis by inhibiting the p53-MDM2 complex, p21Waf1/Cip1, and Bcl-2 proteins. Solasodine has neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic and anti-inflammatory activities .

HY-N0068R

Solasodine (Standard) Purapuridine (Standard); Solancarpidine (Standard); Solasodin (Standard)	Reference Standards MDM-2/p53 Fungal E1/E2/E3 Enzyme Apoptosis	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Solasodine (Standard) is the analytical standard of Solasodine. This product is intended for research and analytical applications. Solasodine (Purapuridine) is a steroidal alkaloid that occurs in plants of the Solanaceae family. Solasodine has neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic and anti-inflammatory activities .

HY-W751400

Solasodine hydrochloride Purapuridine hydrochloride; Solancarpidine hydrochloride; Solasodin hydrochloride	MDM-2/p53 E1/E2/E3 Enzyme Fungal Apoptosis	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Solasodine (Purapuridine) hydrochloride is a steroidal alkaloid that occurs in plants of the Solanaceae family. Solasodine hydrochloride induces apoptosis by inhibiting the p53-MDM2 complex, p21Waf1/Cip1, and Bcl-2 proteins. Solasodine hydrochloride has neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic and anti-inflammatory activities .

HY-N0069R

Solamargine (Standard) Solamargin (Standard); δ-Solanigrine (Standard)	P-glycoprotein Reference Standards Apoptosis	Cancer
Solamargine (Standard) is the analytical standard of Solamargine. This product is intended for research and analytical applications. Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. Solamargine significantly inhibits migration and invasion of HepG2 cells by down-regulating MMP-2 and MMP-9 expression and activity .

HY-W017378R

Trimethylhydroquinone (Standard)	Drug Intermediate Reference Standards	Others
Solamargine (Standard) is the analytical standard of Solamargine. This product is intended for research and analytical applications. Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. Solamargine significantly inhibits migration and invasion of HepG2 cells by down-regulating MMP-2 and MMP-9 expression and activity .

HY-N19216

Solasodiene	Others	Others
Solasodiene is an alkaloid. Solasodiene can be isolated from fruits collected in Mozambique .

HY-N19234

Solanaviol	Others	Others
Solanaviol is a spirosolane-type steroidal alkaloid found in the leaves of Solanum aviculare. Alkaloids are a large class of complex nitrogen-containing basic organic compounds. As food, nutritional supplements, and medicines, alkaloids play an important role in medicine and other fields. Alkaloid compounds exhibit good biological activities in anti-inflammatory, anticancer, analgesic, local anesthetic, neuropharmacological, antibacterial, and antifungal properties .

Solamargine 10+ Cited Publications Solamargin; δ-Solanigrine	Alkaloids Piperidine Alkaloids Solanum Classification of Application Fields Solanaceae Plants Disease Research Fields Saccharides Steroids Cancer	P-glycoprotein Apoptosis
Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. Solamargine significantly inhibits migration and invasion of HepG2 cells by down-regulating MMP-2 and MMP-9 expression and activity .

*Solasodine* 5 Publications Verification Purapuridine; Solancarpidine; Solasodin	Infection Cardiovascular Disease Alkaloids Piperidine Alkaloids Neurological Disease Classification of Application Fields Solanum nigrum Linn. Solanaceae Plants Inflammation/Immunology Disease Research Fields Source Classification	MDM-2/p53 Fungal E1/E2/E3 Enzyme Apoptosis
Solasodine (Purapuridine) is a steroidal alkaloid that occurs in plants of the Solanaceae family. Solasodine induces apoptosis by inhibiting the p53-MDM2 complex, p21Waf1/Cip1, and Bcl-2 proteins. Solasodine has neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic and anti-inflammatory activities .

Solasodine (Standard) Purapuridine (Standard); Solancarpidine (Standard); Solasodin (Standard)	Alkaloids Piperidine Alkaloids Structural Classification Solanum nigrum Linn. Solanaceae Plants Source Classification	Reference Standards MDM-2/p53 Fungal E1/E2/E3 Enzyme Apoptosis
Solasodine (Standard) is the analytical standard of Solasodine. This product is intended for research and analytical applications. Solasodine (Purapuridine) is a steroidal alkaloid that occurs in plants of the Solanaceae family. Solasodine has neuroprotective, antifungal, hypotensive, anticancer, antiatherosclerotic, antiandrogenic and anti-inflammatory activities .

Solamargine (Standard) Solamargin (Standard); δ-Solanigrine (Standard)	Structural Classification Alkaloids Piperidine Alkaloids Solanum Solanaceae Plants Saccharides Steroids	P-glycoprotein Reference Standards Apoptosis
Solamargine (Standard) is the analytical standard of Solamargine. This product is intended for research and analytical applications. Solamargine, a derivative from the steroidal solasodine in Solanum species, exhibits anticancer activities in numerous types of cancer. Solamargine induces non-selective cytotoxicity and P-glycoprotein inhibition. Solamargine significantly inhibits migration and invasion of HepG2 cells by down-regulating MMP-2 and MMP-9 expression and activity .

Solasodiene	Structural Classification Solanum aculeatissimum Jacq. Solanaceae Plants Steroids Source Classification	Others
Solasodiene is an alkaloid. Solasodiene can be isolated from fruits collected in Mozambique .

Solanaviol	Structural Classification Solanaceae Plants Solanum laciniatum Aiton Steroids Source Classification	Others
Solanaviol is a spirosolane-type steroidal alkaloid found in the leaves of Solanum aviculare. Alkaloids are a large class of complex nitrogen-containing basic organic compounds. As food, nutritional supplements, and medicines, alkaloids play an important role in medicine and other fields. Alkaloid compounds exhibit good biological activities in anti-inflammatory, anticancer, analgesic, local anesthetic, neuropharmacological, antibacterial, and antifungal properties .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Solasodine

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