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Results for "

ccl22

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

6

Recombinant Proteins

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103364A
    C-021 dihydrochloride
    2 Publications Verification

    		 CCR Inflammation/Immunology
    C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [ 35S]GTPγS from binding to the receptor with an IC50 of 18 nM .
    C-021 dihydrochloride
  • HY-148494
    Tivumecirnon

    FLX475

    		 CCR Inflammation/Immunology Cancer
    Tivumecirnon (FLX475) is an orally active, selective CCR4 antagonist. Tivumecirnon blocks the binding of CCR4 to its ligands, CCL17 and CCL22, thereby reducing Treg infiltration into the tumor microenvironment. Tivumecirnon has antitumor activity .
    Tivumecirnon
  • HY-103364
    C-021
    2 Publications Verification

    		 CCR Inflammation/Immunology
    C-021 is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 effectively prevents human CCL22-derived [ 35S]GTPγS from binding to the receptor with an IC50 of 18 nM .
    C-021
  • HY-174760
    Human CCL22 mRNA

    		mRNA Inflammation/Immunology
    Human CCL22 mRNA encodes the human C-C motif chemokine ligand 22 (CCL22) protein, a cytokine that displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. CCL22 also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes.
    Human CCL22 mRNA
  • HY-RS23137
    Ccl22 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ccl22 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ccl22 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ccl22 Rat Pre-designed siRNA Set A
    Ccl22 Rat Pre-designed siRNA Set A
  • HY-RS02092
    CCL22 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CCL22 Human Pre-designed siRNA Set A contains three designed siRNAs for CCL22 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CCL22 Human Pre-designed siRNA Set A
    CCL22 Human Pre-designed siRNA Set A
  • HY-RS16703
    Ccl22 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Ccl22 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ccl22 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Ccl22 Mouse Pre-designed siRNA Set A
    Ccl22 Mouse Pre-designed siRNA Set A
  • HY-103364AR
    C-021 dihydrochloride (Standard)

    		Reference Standards CCR Inflammation/Immunology
    C-021 (dihydrochloride) (Standard) is the analytical standard of C-021 (dihydrochloride). This product is intended for research and analytical applications. C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM .
    C-021 dihydrochloride (Standard)
  • HY-103364R
    C-021 (Standard)

    		Reference Standards CCR Inflammation/Immunology
    C-021 (Standard) is the analytical standard of C-021. This product is intended for research and analytical applications. C-021 is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor with an IC50 of 18 nM .
    C-021 (Standard)
  • HY-182564
    ST45177901

    		CCR Cancer
    ST45177901 is a CC chemokine receptor 4 (CCR4) antagonist. The combination of ST45177901 and Sorafenib (HY-10201) effectively inhibits the chemotaxis of Treg cells via the CCL22/CCL17-CCR4 signaling pathway, thereby significantly suppressing the growth and metastasis of tumor cells. ST45177901 is applicable to liver cancer research .
    ST45177901

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