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gluten

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By Targets:	Biochemical Assay Reagents (2) Endogenous Metabolite (1) Environmental Pollutants (1) nAChR (1) Opioid Receptor (2) Sirtuin (1)
By Research Areas:	Inflammation/Immunology (3) Metabolic Disease (3) Neurological Disease (3)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P1596

Gluten Exorphin C	Opioid Receptor	Neurological Disease
Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC₅₀ values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.

HY-135783

AT 1001 1 Publications Verification	nAChR	Neurological Disease Metabolic Disease Inflammation/Immunology
AT 1001 is an orally effective α3β4 nicotinic acetylcholine receptor (α3β4 nAChR) antagonist with a K_i value of 2.64 nM. AT 1001 reversibly blocks Epibatidine (HY-101078)-induced inward currents in HEK cells transfected with α3β4 nAChR. AT 1001 dose-dependently blocks nicotine self-administration behavior in rats, alleviates gluten-induced gastrointestinal symptoms, blocks tight junction toxin-induced immune responses, and reduces the incidence of type 1 diabetes in rats. AT 1001 can be used in the research of nicotine addiction and celiac disease .

HY-W763569

Gluten, Wheat	Environmental Pollutants Biochemical Assay Reagents	Metabolic Disease
Gluten, Wheat is a cohesive, visco-elastic proteinaceous material that can be extrated from wheat. Gluten, Wheat can be used to induce celiac disease .

HY-P1742

Gluten Exorphin B5	Opioid Receptor	Metabolic Disease
Gluten Exorphin B5 is an exogenous opioid peptides derived from wheat gluten, acts on opioid receptor, increases postprandial plasma insulin level in rats .

HY-N16331

Soybean flour	Others	Others
Soybean flour is a defatted and slowly available protein nutrient. Soybean flour can be isolated from the leguminous plant soybean. Soybean flour has antioxidant activity and stabilizes lipids in formulated foods. Soybean flour can be used for food production such as gluten-free bread research .

HY-159703

Glu-Cys Glutamyl-cysteine; PSSGlu-Cys	Endogenous Metabolite	Others
Glu-Cys (Glutamyl-cysteine; PSSGlu-Cys) is a dipeptide composed of L-glutamic acid (HY-14608) and L-cysteine (HY-Y0337) joined by a peptide linkage .

HY-177878

IMU-856	Sirtuin	Inflammation/Immunology
IMU-856 is an orally active and systemic action SIRT6 small molecule regulator. IMU-856 effectively and selectively inhibits the deacetylase activity of SIRT6, while increasing the protein level of SIRT6. IMU-856 can restore intestinal barrier function and can be used for research on celiac disease .

HY-W355779A

Hydrolyzed Gliadin	Biochemical Assay Reagents	Others
Hydrolyzed Gliadin is a major component of the gluten, comprises a class of prolamines produced by plants of the Triticum genus. Gliadin could induce celiac disease .

Cat. No.	Product Name	Type

HY-W763569

Gluten, Wheat	Biochemical Assay Reagents
Gluten, Wheat is a cohesive, visco-elastic proteinaceous material that can be extrated from wheat. Gluten, Wheat can be used to induce celiac disease .

HY-W355779A

Hydrolyzed Gliadin	Biochemical Assay Reagents
Hydrolyzed Gliadin is a major component of the gluten, comprises a class of prolamines produced by plants of the Triticum genus. Gliadin could induce celiac disease .

Cat. No.	Product Name	Target	Research Area

HY-P1999

α-Gliadin (43-49) Gliadorphin	Peptides	Inflammation/Immunology
α-Gliadin (43-49) is the major protein component of gluten. α-Gliadin (43-49) can be used in the immunological response to α-gliadin .

HY-P1596

Gluten Exorphin C	Opioid Receptor	Neurological Disease
Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC₅₀ values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.

HY-P1742

Gluten Exorphin B5	Opioid Receptor	Metabolic Disease
Gluten Exorphin B5 is an exogenous opioid peptides derived from wheat gluten, acts on opioid receptor, increases postprandial plasma insulin level in rats .

HY-P5070

Gluten Exorphin A5	Peptides	Neurological Disease
Gluten Exorphin A5 is a fragment from wheat gluten with neuroprotective effects. Gluten Exorphin A5 produces various effects not only in the peripheral nervous systems but also in the central nervous system .

HY-159703

Glu-Cys Glutamyl-cysteine; PSSGlu-Cys	Endogenous Metabolite	Others
Glu-Cys (Glutamyl-cysteine; PSSGlu-Cys) is a dipeptide composed of L-glutamic acid (HY-14608) and L-cysteine (HY-Y0337) joined by a peptide linkage .

Gluten Exorphin B5	Natural Products Monophenols Classification of Application Fields Agrostidoideae Phenols Metabolic Disease Plants Disease Research Fields Triticum aestivum L. Source Classification	Opioid Receptor
Gluten Exorphin B5 is an exogenous opioid peptides derived from wheat gluten, acts on opioid receptor, increases postprandial plasma insulin level in rats .

Soybean flour	Natural Products Leguminosae Glycine max (L.) merr Plants Source Classification	Others
Soybean flour is a defatted and slowly available protein nutrient. Soybean flour can be isolated from the leguminous plant soybean. Soybean flour has antioxidant activity and stabilizes lipids in formulated foods. Soybean flour can be used for food production such as gluten-free bread research .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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