1. GPCR/G Protein
    Neuronal Signaling
  2. Opioid Receptor

Gluten Exorphin C 

Cat. No.: HY-P1596
Handling Instructions

Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Gluten Exorphin C Chemical Structure

Gluten Exorphin C Chemical Structure

CAS No. : 142479-62-7

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1 mg USD 110 Get quote
5 mg USD 190 Get quote
10 mg USD 290 Get quote
25 mg USD 590 Get quote

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.

IC50 & Target

IC50: 40 μM (μ opioid), 13.5 μM (δ opioid)[1]

In Vitro

Gluten exorphin C, a novel opioid peptide, is isolated from the pepsin-trypsin-chymotrypsin digest of wheat gluten. Gluten exorphin C is evaluated its opioid activities by the GPI and MVD assays and its receptor affinities by radioreceptor assays. Its IC50s are 40 μM and 13.5 μM in the GPI and the MVD assays, respectively. Gluten exorphin C has a structure quite different from any of the endogenous and exogenous opioid peptides ever reported in that the N terminal Tyr is the only aromatic amino acid. The analogs containing Tyr-Pro-X-Ser-Leu are synthesized to study its structure-activity relationship. Peptides in which X is an aromatic amino acid or an aliphatic hydrophobic amino acid has opioid activity[1].

Solvent & Solubility
In Vitro: 

10 mM in H2O

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6900 mL 8.4502 mL 16.9005 mL
5 mM 0.3380 mL 1.6900 mL 3.3801 mL
10 mM 0.1690 mL 0.8450 mL 1.6900 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

591.70

Formula

C₂₉H₄₅N₅O₈

CAS No.

142479-62-7

Sequence

Tyr-Pro-Ile-Ser-Leu

Sequence Shortening

YPISL

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Gluten Exorphin C
Cat. No.:
HY-P1596
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Gluten Exorphin C

Cat. No.: HY-P1596