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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
human subjects
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "human subjects" in MCE Product Catalog:
4
4 Cited Publications
Synonyms: Sodium p-aminohippurate; p-Aminohippuric acid sodium salt
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Aminohippurate sodium (Sodium p-aminohippurate) is a renal tubular transport inhibitor and a substrate for organic anion transporters. Aminohippurate sodium inhibits renal tubular reabsorption of phosphate and promotes increased urinary phosphate excretion. Aminohippurate sodium inhibits renal tubular reabsorption of vitamin C as well as the transport of glucose .
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Cat. No.: HY-N0821
CAS No.: 63492-69-3
Synonyms: Griffonin
Category:
Natural Products Ranunculaceae Semiaquilegia adoxoides(DC. ) Mak. Plants Disease Research Fields Cancer
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Cat. No.: HY-108229
CAS No.: 49625-89-0
Synonyms: 6β-Hydroxynaltrexone
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6β-Naltrexol (6β-Hydroxynaltrexone), the primary metabolite of Naltrexone, is a peripherally selective opioid antagonist. 6β-Naltrexol selectively inhibits gastrointestinal opioid effects in human subjects and inhibits Morphine-induced slowing of gastrointestinal transit .
Cat. No.: HY-108229S
CAS No.: 1435727-11-9
Synonyms: 6β-Hydroxynaltrexone-d3
Cat. No.: HY-148795
CAS No.: 2460667-52-9
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Ritivixibat is an apical sodium-dependent bile acid transporter (ASBT/IBAT) inhibitor. Ritivixibat blocks ASBT/IBAT function, thereby reducing bile acid reabsorption, regulating bile acid homeostasis and alleviating liver injury. Ritivixibat protects cholangiocytes from damage caused by cytotoxic bile acids. Ritivixibat is applicable to research related to primary sclerosing cholangitis .
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Cat. No.: HY-N2086S
CAS No.: 1215721-57-5
Synonyms: Ethyl hexadecanoate-d31
Cat. No.: HY-171195
CAS No.: 1235656-95-7
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VU0631019 is a potent antagonist of 5-HT2B, with the IC50 of 29 nM. VU0631019 is predicted to have very limited potential for brain penetration in human subjects, as is predicted to be substrates for P-gp-mediated efflux in humans .
Cat. No.: HY-171194
CAS No.: 1396886-30-8
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VU0530244 is a potent antagonist of 5-HT2B, with the IC50 of 17.3 nM. VU0530244 is predicted to have very limited potential for brain penetration in human subjects, as is predicted to be substrates for P-gp-mediated efflux in humans .
Cat. No.: HY-123429
CAS No.: 83539-21-3
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CK0683A is a novel biaminourea antibiotic with antiplaque effects and demonstrated efficacy in experimental mouse dental disease models. A 12-week study in beagles compared its efficacy in terms of plaque and gingivitis reduction, staining potential, and safety. Dogs were selected as the study subjects because the onset and progression of canine periodontal disease is similar to that of humans. As a positive control for plaque and gingivitis reduction and staining, chlorhexidine acetate was selected because it is effective in both humans and dogs.
Cat. No.: HY-123479
CAS No.: 64169-11-5
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CK0492B is a novel biaminourea antibiotic that has antiplaque properties in vitro and has shown efficacy in an experimental mouse dental disease model. A 12-week study in beagles compared its efficacy in reducing plaque and gingivitis, staining potential, and safety. Dogs were selected as the study subjects because the onset and progression of canine periodontal disease are similar to humans. Chlorhexidine acetate was selected as a positive control for plaque and gingivitis reduction and staining because it is effective in both humans and dogs.
Cat. No.: HY-145545
CAS No.: 131350-53-3
Synonyms: PE(18:0/22:4); 1-Stearoyl-2-Docosatraenoyl-sn-glycero-3-PE
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1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) and adrenic acid (HY-W013215) at the sn-1 and sn-2 positions, respectively. 1-Stearoyl-2-adrenoyl-sn-glycero-3-PE levels are inversely correlated with subject age in mitochondria isolated from human post-mortem hippocampus.
Cat. No.: HY-N0821R
CAS No.: 63492-69-3
Synonyms: Griffonin (Standard)
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Cat. No.: HY-127147
CAS No.: 49564-56-9
Synonyms: AH 8165 bromide
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Fazadinium bromide (AH 8165 bromide) is a species-specific neuromuscular blocking agent that primarily targets the acetylcholine receptor (AChR) at the skeletal neuromuscular junction, blocking the receptor agonist binding site in a competitive and reversible manner. Fazadinium bromide induces sustained tetanic fade, and tetanic contractions are more sensitive than single twitches. Fazadinium bromide can be used in anesthesia and research related to neuromuscular transmission .
Cat. No.: HY-W611602
CAS No.: 17451-62-6
Synonyms: N-Me-His-OH (hydrochloride)
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N-Methyl-L-histidine (N-Me-His-OH) hydrochloride is a derivative of histidine, and a urinary metabolite with statistically significant differences in urinary secretion between male and female human .
Cat. No.: HY-W209580
CAS No.: 60599-38-4
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N-Nitrosobis (2-oxopropyl) amine is a nitrosamine compound that has been the subject of significant research interest in the field of chemical carcinogenesis. N-nitrosobis (2-oxopropyl) amine (BOP) -treated Syrian golden hamsters are a chemical carcinogenesis model that represents human pancreatic cancer.
Cat. No.: HY-E72107
Human UGT1A4 is a UDP-glucuronosyltransferase. Human UGT1A4 is the major enzyme catalyzing the glucuronidation of 25-hydroxyvitamin D3 (HY-32351) in the liver, and maintains vitamin D homeostasis by clearing 25-hydroxyvitamin D3. Human UGT1A4 regulates the substrate-dependent enzymatic activities of UGT1A1 and UGT1A6, while its own activity is also subject to substrate-dependent regulation by co-expressed UGT1A1 and UGT1A6 .
Cat. No.: HY-P992150
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Cat. No.: HY-P992007
Synonyms: RN909
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
