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mecA

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenosine Receptor (6) Antibiotic (1) Apoptosis (1) Bacterial (2) Fluorescent Dye (3)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (5) Neurological Disease (1)
Click Chemistry:	Labeling and Fluorescence Imaging (1) Azide (3)

11

Inhibitors & Agonists

3

Fluorescent Dye

2

Inhibitory Antibodies

1

Natural
Products

1

Recombinant Proteins

3

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

AB-MECA	Adenosine Receptor	Neurological Disease
AB-MECA is a high affinity A₃ adenosine receptor agonist with a binding K_i of 430.5 nM for human A₃ receptors in CHO cells. AB-MECA can enhance plasma histamine level .

Piclidenoson 3 Publications Verification IB-mecA; CF-101	Adenosine Receptor Apoptosis	Inflammation/Immunology Cancer
Piclidenoson (IB-MECA) is a first-in-class, orally active and selective A3 adenosine receptor (A3AR) agonist. Piclidenoson exhibits antiproliferative effect and induces apoptosis in different cancer cell types like melanoma, leukemia. Piclidenoson can be used for the research of autoimmune inflammatory diseases and COVID-19 .

Namodenoson CF-102; 2-Cl-IB-mecA	Adenosine Receptor	Cancer
Namodenoson (CF-102) is a selective A3 adenosine receptor (A3AR) agonist (K_i=0.33 nM). Namodenoson displays 2500- and 1400-fold selectivity over A1 and A2A receptors respectively .

Oxacillin sodium monohydrate 5+ Cited Publications	Bacterial Antibiotic	Infection
Oxacillin sodium monohydrate is an antibiotic similar to Flucloxacillin used in resistant staphylococci infections study .

HY-N8151

Sanguisorbigenin

Bacterial Infection

Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA) .

A3AR modulator 1	Adenosine Receptor	Inflammation/Immunology
A3AR modulator 1 (MRS8054) is an orally active A3 adenosine receptor (A3AR) (Adenosine Receptor) positive allosteric modulator (PAM). A3AR modulator 1 greatly enhances Cl-IB-MECA-stimulated [ ³⁵S]GTPγS binding E_max .

MRE3008F20	Adenosine Receptor	Inflammation/Immunology
MRE3008F20 is a highly efficient, highly selective and radioactive adenosine A₃ receptor (AA₃R) antagonist (K_i=1.8 nM). MRE3008F20 effectively antagonises Cl-IB-MECA-induced cAMP production in resting lymphocytes with an IC₅₀ value of 5 nM. MRE3008F20 can be used in the study of AA3R .

MRS1334	Adenosine Receptor	Cardiovascular Disease
MRS1334 is a potent and selective human adenosine A₃ receptor antagonist with K_is of 2.69 nM, >100 nM, >100 nM for hA₃, rA₁, rA_2A, respectively. MRS1334 blocks the protective effect of Cl-IB-MECA leading to significant bradycardia and elevated ST segment . MRS1334 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Sulfo-cyanine3 azide TEA	Fluorescent Dye	Inflammation/Immunology
Sulfo-cyanine3 azide TEA is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide TEA can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents .

Sulfo-cyanine3 azide	Fluorescent Dye	Inflammation/Immunology
Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents .

Sulfo-cyanine3 azide sodium	Fluorescent Dye	Others
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents .

Cat. No.	Product Name	Type

Sulfo-cyanine3 azide TEA	Fluorescent Dyes/Probes
Sulfo-cyanine3 azide TEA is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide TEA can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents .

Sulfo-cyanine3 azide	Fluorescent Dyes/Probes
Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents .

Sulfo-cyanine3 azide sodium	Fluorescent Dyes/Probes
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents .

Cat. No.	Product Name	Target	Research Area

*Anti-Mouse Pan-endothelial Cell Antigen/MECA-32 Antibody (MECA-32)*	Inhibitory Antibodies	Others
Anti-Mouse Pan-endothelial Cell Antigen/MECA-32 Antibody (MECA-32) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse Pan-endothelial Cell Antigen/MECA-32.

*Anti-Mouse MAdCAM-1 Antibody (MECA-367)*	Inhibitory Antibodies	Others
Anti-Mouse MAdCAM-1 Antibody (MECA-367) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse MAdCAM-1.

Cat. No.	Compare	Product Name	Species	Source

	MecA Protein, S. aureus (His-SUMO) mecA; MW0880Adapter protein mecA	Staphylococcus aureus	E. coli
	The MecA protein plays a crucial role in cellular machinery by facilitating the recognition and targeting of unfolded and aggregated proteins, directing them to the ClpC protease or other proteins involved in proteolysis. The function of this protein is critical for the efficient removal and degradation of abnormal proteins, ensuring cellular homeostasis and preventing the accumulation of potentially harmful protein aggregates. MecA Protein, S. aureus (His-SUMO) is the recombinant Staphylococcus aureus-derived MecA protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of MecA Protein, S. aureus (His-SUMO) is 239 a.a., with molecular weight of ~44.3 kDa.

Cat. No.	Product Name		Classification

Sulfo-cyanine3 azide TEA		Azide
Sulfo-cyanine3 azide TEA is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide TEA can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents .

Sulfo-cyanine3 azide		Azide
Sulfo-cyanine3 azide is an azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents .

Sulfo-cyanine3 azide sodium		Labeling and Fluorescence Imaging Azide
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents .

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