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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
photoactive
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "photoactive" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: Lauryl Maltoside
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N-Dodecyl-β-D-maltoside (Lauryl Maltoside) is a non-ionic detergent. N-Dodecyl-β-D-maltoside has strong adsorption on alumina, titanium dioxide and hematite. N-Dodecyl-β-D-maltoside can promote the reactivation of various proteins. N-Dodecyl-β-D-maltoside can effectively stabilize photoactive reaction center complexes (RCs) and inhibit the degradation of Rhodopseudomonas spheroides R-26 reaction center in solution. N-Dodecyl-β-D-maltoside can be used for purification and stabilization of RNA polymerase and for detection of protein-lipid interactions .
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1 Cited Publications
Cat. No.: HY-A0169A
CAS No.: 79416-27-6
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Methyl aminolevulinate hydrochloride is a sensitizer used in photodynamic therapy (PDT). Methyl aminolevulinate hydrochloride penetrates the skin and induces the production of photoactive porphyrins including protoporphyrin IX in cells; upon exposure to appropriate light, it generates ROS, which triggers cellular oxidation and cell death. Methyl aminolevulinate hydrochloride acts as a photo-damage reversing agent through epidermal reconstruction, cytokine-mediated activation of dermal fibroblasts, elastin breakdown, new collagen formation, and compression of dilated capillaries. Methyl aminolevulinate hydrochloride reduces the expression of the proliferation marker Ki-67 and the early skin carcinogenesis marker TP53. Methyl aminolevulinate hydrochloride delays the onset of ultraviolet-induced skin tumors and reduces tumor burden in hairless mice. Methyl aminolevulinate hydrochloride is applicable to research related to actinic keratosis and basal cell carcinoma .
Cat. No.: HY-128974S
CAS No.: 849110-74-3
Synonyms: Lauryl Maltoside-d25
Cat. No.: HY-157084
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HS-291 is a HtpG inhibitor of Borrelia burgdorferi (Bb). HS-291 contains BX-2819 (high affinity for Bb HtpG), PEG linker, and Verteporfin (HY-B0146) (a photoactive toxin).HS-291 produces reactive oxygen species under light activation to oxidize HtpG and a discrete protein subset near chaperone proteins and can quickly and irreversibly inactivate Bb .
Cat. No.: HY-W016174S
CAS No.: 180802-01-1
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Diphenyl sulfide-d1 is the d1-labeled Diphenyl sulfide (HY-W016174). Diphenyl sulfide is an additive for organic photovoltaic devices. Diphenyl sulfide modulates vertical composition distribution of PTB7-Th:PC71BM photoactive layers, promoting enrichment of PTB7-Th at the upper surface and PC71BM at the bottom. Diphenyl sulfide promotes ordered molecular packing and crystallinity of PTB7-Th:PC71BM photoactive layers, including more compact π−π stacking of PTB7-Th. Diphenyl sulfide improves exciton dissociation, charge transport, and charge collection in PTB7-Th:PC71BM-based inverted polymer solar cells. Diphenyl sulfide acts as a solvent additive to improve the photovoltaic performance of inverted organic photovoltaic devices .
Cat. No.: HY-169217
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CYP3A4-IN-4 (compound Δ,Λ-3), a Ru(II) Ir(III) Conjugate, is a photoactive inhibitor of the major human drug metabolizing enzyme CYP3A4. CYP3A4-IN-4 containing the [Ru(tpy)(Me2bpy)] photocaging group showed an IC50 of 2.2 μM for inhibition of microsomal CYP3A4 under light conditions (λirr=530 nm, tirr=15 min) .
Cat. No.: HY-D3157
CAS No.: 2133002-04-5
Cat. No.: HY-D3240
CAS No.: 2375541-43-6
Cat. No.: HY-157317
CAS No.: 3014356-10-3
Antitumor agent-126 (Compound II4) is a photoactive (IC50= 0.149) anticancer agent with significant near-infrared fluorescence emission at 650-760 nm. Antitumor agent-126 has antiproliferative activity and can induce apoptosis after laser irradiation. Antitumor agent-126 effectively inhibits tumor growth in mouse xenograft models exposed to 650 nm laser irradiation. Antitumor agent-126 can be used in cancer research .
Cat. No.: HY-147150
CAS No.: 150424-94-5
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8-Azido-cADPR, with its photoactive azido group, is a potent photoaffinity probe. 8-Azido-cADPR can be used for the identification and characterization of cADPR-binding proteins . 8-Azido-cADPR is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-A0169
CAS No.: 33320-16-0
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Methyl aminolevulinate is a sensitizer used in photodynamic therapy (PDT). Methyl aminolevulinate penetrates the skin and induces the production of photoactive porphyrins including protoporphyrin IX in cells; upon exposure to appropriate light, it generates ROS, which triggers cellular oxidation and cell death. Methyl aminolevulinate acts as a photo-damage reversing agent through epidermal reconstruction, cytokine-mediated activation of dermal fibroblasts, elastin breakdown, new collagen formation, and compression of dilated capillaries. Methyl aminolevulinate reduces the expression of the proliferation marker Ki-67 and the early skin carcinogenesis marker TP53. Methyl aminolevulinate delays the onset of ultraviolet-induced skin tumors and reduces tumor burden in hairless mice. Methyl aminolevulinate is applicable to research related to actinic keratosis and basal cell carcinoma .
Cat. No.: HY-W016174
CAS No.: 139-66-2
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Diphenyl sulfide is an additive for organic photovoltaic devices. Diphenyl sulfide modulates vertical composition distribution of PTB7-Th:PC71BM photoactive layers, promoting enrichment of PTB7-Th at the upper surface and PC71BM at the bottom. Diphenyl sulfide promotes ordered molecular packing and crystallinity of PTB7-Th:PC71BM photoactive layers, including more compact π−π stacking of PTB7-Th. Diphenyl sulfide improves exciton dissociation, charge transport, and charge collection in PTB7-Th:PC71BM-based inverted polymer solar cells. Diphenyl sulfide acts as a solvent additive to improve the photovoltaic performance of inverted organic photovoltaic devices .
Cat. No.: HY-183342
CAS No.: 1216903-70-6
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DHEA Benzophenone-biotin is a photoactive DHEA (HY-14650) analog containing Biotin (HY-B0511) and Benzophenone (HY-Y0546) groups. DHEA Benzophenone-biotin inhibits plasma membrane binding of DHEA, activates endothelial NO synthase. DHEA Benzophenone-biotin cross-links to plasma membrane DHEA binding sites upon UV irradiation to identify associated proteins .
Cat. No.: HY-182785
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Photosensitizer-10 is a glutathione (GSH)-activatable photosensitizer. Photosensitizer-10 shows minimal photoactivity in the absence of glutathione, and generates a highly active species upon reaction with glutathione to induce photo-cytotoxicity. Photosensitizer-10 exhibits selective photo-cytotoxicity toward cancer cells with elevated intracellular glutathione levels while sparing normal cells. Photosensitizer-10 can be used for the research of cancer, such as lung carcinoma and skin carcinoma .
Cat. No.: HY-A0169AR
CAS No.: 79416-27-6
Research Areas:
Methyl aminolevulinate hydrochloride (Standard) is the analytical standard of Methyl aminolevulinate hydrochloride. This product is intended for research and analytical applications. Methyl aminolevulinate hydrochloride is a sensitizer used in photodynamic therapy (PDT). Methyl aminolevulinate hydrochloride penetrates the skin and induces the production of photoactive porphyrins including protoporphyrin IX in cells; upon exposure to appropriate light, it generates ROS, which triggers cellular oxidation and cell death. Methyl aminolevulinate hydrochloride acts as a photo-damage reversing agent through epidermal reconstruction, cytokine-mediated activation of dermal fibroblasts, elastin breakdown, new collagen formation, and compression of dilated capillaries. Methyl aminolevulinate hydrochloride reduces the expression of the proliferation marker Ki-67 and the early skin carcinogenesis marker TP53. Methyl aminolevulinate hydrochloride delays the onset of ultraviolet-induced skin tumors and reduces tumor burden in hairless mice. Methyl aminolevulinate hydrochloride is applicable to research related to actinic keratosis and basal cell carcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
