Photoactive NTR probe
Photoactive NTR probe (Compound 1) is a covalent crosslinker and Fluorescent indicator targeting Nitroreductase. The Photoactive NTR probe undergoes a sequential activation process: it is first activated via nitroreductase-mediated nitro-to-amino conversion, and then forms a fluorescent product upon photoactivation. The Photoactive NTR probe can form covalent adducts with the side chains of cysteine, tyrosine, lysine and histidine in adjacent proteins to reduce fluorophore diffusion. The Photoactive NTR probe enables super-resolution (STORM) imaging of active mitochondrial nitroreductase microdomains in living cells.
For research use only. We do not sell to patients.
- CAS No.: 2375541-43-6
- Formula: C25H20N4O4
- Molecular Weight:440.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2375541-43-6
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Molecular Weight 440.45
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Formula C25H20N4O4
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SMILES
O=C(C1=[N+]=[N-])C2=C(C=CC=C2)C31C4=C(C=C(N(CC)CC)C=C4)OC5=C3C=CC([N+]([O-])=O)=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Photoactive NTR probe Related Classifications
HY-D3240 Related Classifications
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