purinoceptor

By Targets:	Endogenous Metabolite (5) Interleukin Related (1) Isotope-Labeled Compounds (3) P2X Receptor (1) P2Y Receptor (1)
By Research Areas:	Cardiovascular Disease (1) Inflammation/Immunology (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W010791

Adenosine 5'-diphosphate sodium salt	Endogenous Metabolite	Others
Adenosine 5'-diphosphate (ADP) sodium salt is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors .

HY-W010918

Adenosine 5'-diphosphate Adenosine diphosphate; ADP	Endogenous Metabolite	Others
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-18725A

P2X7-IN-2 TFA	P2X Receptor Interleukin Related	Cardiovascular Disease Inflammation/Immunology
P2X7-IN-2 TFA (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 TFA inhibits IL-Iβ release with an IC₅₀ value of 0.01 nM. P2X7-IN-2 TFA can be used for the research of autoimmunity, inflammation and cardiovascular disease .

HY-108662

PIT 2,2'-Pyridylisatogen tosylate	P2Y Receptor	Inflammation/Immunology
PIT (2,2'-Pyridylisatogen tosylate) is a selective and non-competitive antagonist of P2Y1 receptor with an IC₅₀ value of 0.14 μM for human P2Y1 receptor. PIT antagonizes P2Y1 receptor signaling without affecting nucleotide binding. PIT is an irreversible antagonist of responses to ATP at metabotropic purinoceptors (of the P2Y family) in some smooth muscles. PIT can be used for the research of chronic bronchitis and asthma .

HY-101077

Iso-PPADS tetrasodium
Iso-PPADS tetrasodium is a *P2X-purinoceptor* antagonist. Iso-PPADS tetrasodium inhibits P2X1 and P2X3 receptor with IC₅₀s of 43 nM and 84 nM. Iso-PPADS tetrasodium is protective against ventilator-induced brain injury (VIBI) .

HY-W010918S

Adenosine 5'-diphosphate-d13 dilithium Adenosine diphosphate-d¹³ dilithium; ADP--d¹³ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine 5'-diphosphate-d₁₃ (Adenosine diphosphate-d₁₃ dilithium; ADP-d₁₃) dilithium is deuterium labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-W010918S1

Adenosine 5'-diphosphate-13C10 dilithium Adenosine diphosphate-¹³C₁₀ dilithium; ADP-¹³C₁₀ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine 5'-diphosphate- ¹³C₁₀ (Adenosine diphosphate- ¹³C₁₀ dilithium; ADP- ¹³C₁₀) dilithium is ¹³C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-W010918S2

Adenosine 5'-diphosphate-15N5 dilithium Adenosine diphosphate-¹⁵N₅ dilithium; ADP-¹⁵N₅ dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Others
Adenosine 5'-diphosphate- ¹⁵N₅ (Adenosine diphosphate- ¹⁵N₅ dilithium; ADP- ¹⁵N₅) dilithium is ¹⁵N labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W010791

Adenosine 5'-diphosphate sodium salt	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Adenosine 5'-diphosphate (ADP) sodium salt is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors .

HY-W010918

Adenosine 5'-diphosphate Adenosine diphosphate; ADP	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite
Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

Species:	Human (3) Mouse (3)
Tag:	His (5) Flag (2)
Source:	E. coli Cell-free (4) Sf9 insect cells (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P702409

	P2RY1 Protein, Mouse (Cell-Free, His) P2Y purinoceptor 1; ADP receptor; Purinergic receptor	Mouse	E. coli Cell-free
	The P2RY1 Protein serves as a receptor for extracellular adenine nucleotides, particularly ADP. In platelets, ADP binding to P2RY1 triggers intracellular calcium mobilization through phospholipase C activation, inducing platelet shape changes and culminating in platelet aggregation. P2RY1 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived P2RY1 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of P2RY1 Protein, Mouse (Cell-Free, His) is 373 a.a., with molecular weight of 48.3 kDa.

HY-P702411

	P2RY12 Protein, Mouse (Cell-Free, His) P2Y purinoceptor 12; P2Y12	Mouse	E. coli Cell-free
	P2RY12 protein is a receptor for ADP and ATP and inhibits adenylyl cyclase second messenger system through G protein. P2RY12 is critical for normal platelet aggregation and coagulation, where it mediates responses to nucleotide signals. P2RY12 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived P2RY12 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of P2RY12 Protein, Mouse (Cell-Free, His) is 347 a.a., with molecular weight of 45.5 kDa.

HY-P702412

	P2RY13 Protein, Mouse (Cell-Free, His) P2Y purinoceptor 13; G-protein coupled receptor 86	Mouse	E. coli Cell-free
	P2RY13 Protein, a receptor for adenosine diphosphate (ADP), is coupled to G(i)-proteins. Its potential role in hematopoiesis and the immune system implies significance in processes related to blood cell formation and immune response regulation. P2RY13 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived P2RY13 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of P2RY13 Protein, Mouse (Cell-Free, His) is 377 a.a., with molecular weight of 44.8 kDa.

HY-P701629

	P2Y1 Protein, Human (Sf9, FLAG) P2RY1; P2Y purinoceptor 1; P2Y1; ADP receptor; Purinergic receptor	Human	Sf9 insect cells
	The P2Y1 protein acts as a receptor for extracellular adenine nucleotides, specifically ADP. In platelets, ADP binding activates phospholipase C, leading to intracellular calcium mobilization, platelet shape changes, and aggregation. P2Y1 Protein, Human (Sf9, FLAG) is the recombinant human-derived P2Y1 protein, expressed by Sf9 insect cells , with N-Flag labeled tag. The total length of P2Y1 Protein, Human (Sf9, FLAG) is 372 a.a., .

HY-P701630

	P2Y1 Protein, Human (Sf9, FLAG, His) P2RY1; P2Y purinoceptor 1; P2Y1; ADP receptor; Purinergic receptor	Human	Sf9 insect cells
	The P2Y1 protein acts as a receptor for extracellular adenine nucleotides, specifically ADP. In platelets, ADP binding activates phospholipase C, leading to intracellular calcium mobilization, platelet shape changes, and aggregation. P2Y1 Protein, Human (Sf9, FLAG, His) is the recombinant human-derived P2Y1 protein, expressed by Sf9 insect cells , with C-10*His, N-Flag labeled tag. The total length of P2Y1 Protein, Human (Sf9, FLAG, His) is 372 a.a., .

HY-P702410

	P2RY12 Protein, Human (Cell-Free, His) P2Y purinoceptor 12; ADP-glucose receptor; ADPG-R; P2T(AC); P2Y(AC); P2Y(cyc); P2Y12 platelet ADP receptor; P2Y(ADP); SP1999	Human	E. coli Cell-free
	P2RY12 Protein, a receptor for adenosine diphosphate (ADP) and adenosine triphosphate (ATP), inhibits the adenylyl cyclase second messenger system via G-proteins. Unlike uridine diphosphate (UDP) and uridine triphosphate (UTP), P2RY12 crucially regulates platelet aggregation and blood coagulation, serving as a key regulator in these physiological processes. P2RY12 Protein, Human (Cell-Free, His) is the recombinant human-derived P2RY12 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of P2RY12 Protein, Human (Cell-Free, His) is 342 a.a., with molecular weight of 42.2 kDa.


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Cat. No.	Product Name	Chemical Structure

HY-W010918S

Adenosine 5'-diphosphate-d13 dilithium
Adenosine 5'-diphosphate-d₁₃ (Adenosine diphosphate-d₁₃ dilithium; ADP-d₁₃) dilithium is deuterium labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

Adenosine 5'-diphosphate-d13 dilithium

Adenosine 5'-diphosphate-d₁₃ (Adenosine diphosphate-d₁₃ dilithium; ADP-d₁₃) dilithium is deuterium labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-W010918S1

Adenosine 5'-diphosphate-13C10 dilithium
Adenosine 5'-diphosphate- ¹³C₁₀ (Adenosine diphosphate- ¹³C₁₀ dilithium; ADP- ¹³C₁₀) dilithium is ¹³C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

Adenosine 5'-diphosphate-13C10 dilithium

Adenosine 5'-diphosphate- ¹³C₁₀ (Adenosine diphosphate- ¹³C₁₀ dilithium; ADP- ¹³C₁₀) dilithium is ¹³C-labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

HY-W010918S2

Adenosine 5'-diphosphate-15N5 dilithium
Adenosine 5'-diphosphate- ¹⁵N₅ (Adenosine diphosphate- ¹⁵N₅ dilithium; ADP- ¹⁵N₅) dilithium is ¹⁵N labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

Adenosine 5'-diphosphate-15N5 dilithium

Adenosine 5'-diphosphate- ¹⁵N₅ (Adenosine diphosphate- ¹⁵N₅ dilithium; ADP- ¹⁵N₅) dilithium is ¹⁵N labeled Adenosine 5'-diphosphate (HY-W010918). Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P_2T-purinoceptors.

Cat. No.	Product Name	Application	Reactivity

HY-P81901

OXGR1 Antibody (YA1646)

P2Y15; Alpha-ketoglutarate receptor 1; G-protein coupled receptor 80; G-protein coupled receptor 99; P2Y purinoceptor 15
WB Human, Rat

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