1. Iso-PPADS tetrasodium

Iso-PPADS tetrasodium is a P2X-purinoceptor antagonist. Iso-PPADS tetrasodium inhibits P2X1 and P2X3 receptor with IC50s of 43 nM and 84 nM. Iso-PPADS tetrasodium is protective against ventilator-induced brain injury (VIBI).

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Iso-PPADS tetrasodium Chemical Structure

Iso-PPADS tetrasodium Chemical Structure

CAS No. : 207572-67-6

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Description

Iso-PPADS tetrasodium is a P2X-purinoceptor antagonist. Iso-PPADS tetrasodium inhibits P2X1 and P2X3 receptor with IC50s of 43 nM and 84 nM. Iso-PPADS tetrasodium is protective against ventilator-induced brain injury (VIBI)[1][2].

IC50 & Target

43 nM and 84 nM (P2X1 and P2X3 receptor)[2]

Molecular Weight

599.30

Formula

C14H10N3Na4O12PS2

CAS No.
SMILES

O=S(C1=CC=C(S(=O)(O[Na])=O)C=C1/N=N/C2=NC(C)=C(O)C(C=O)=C2COP(O[Na])(O[Na])=O)(O[Na])=O

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Iso-PPADS tetrasodium
Cat. No.:
HY-101077
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