2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Adenosine 5'-diphosphate sodium salt

Adenosine 5'-diphosphate sodium salt 

Cat. No.: HY-W010791 Purity: 99.83%
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Adenosine 5'-diphosphate sodium salt is a nucleoside diphosphate and the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase through its action on P2T-purinergic receptors.

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CAS No. : 20398-34-9

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Based on 9 publication(s) in Google Scholar

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Adenosine 5'-diphosphate sodium salt Related Antibodies

Top Publications Citing Use of Products

    Adenosine 5'-diphosphate sodium salt purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Dec:149:157553.  [Abstract]

    Flow cytometry analysis of CD61 and CD62P expression in ADP (20 μM; 10 min) -stimulated platelets after glycyrrhizin treatment.

    Adenosine 5'-diphosphate sodium salt purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Dec:149:157553.  [Abstract]

    Quantitative analysis of the adhesion thickness of platelets on fibrinogen-coated surfaces after ADP (20 μM) activation, with or without glycyrrhizin treatment.

    Adenosine 5'-diphosphate sodium salt purchased from MedChemExpress. Usage Cited in: Redox Biol. 2024 Jun 8:74:103225.  [Abstract]

    ADP (5 mM; 1 h). Representative Western blots show the protein levels of p-PI3K, PI3K, p-AKT, AKT, p-NRF2, NRF2, GSDMD, and GSDMD-N in different groups.

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    Description

    Adenosine 5'-diphosphate sodium salt is a nucleoside diphosphate and the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase through its action on P2T-purinergic receptors[1][2].

    IC50 & Target

    Human Endogenous Metabolite

     

    In Vitro

    Adenosine 5'-diphosphate sodium salt potently induces full maximal aggregation of human platelets, with a pA50 of 5.87[2].
    Adenosine 5'-diphosphate sodium salt (5 μM; 30 seconds) inhibits the prostaglandin E1 (PGE1)-stimulated adenylate cyclase activity in human platelets by 71%[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Adenosine 5'-diphosphate sodium salt Related Antibodies
    Clinical Trial
    Formula

    C10H15N5O10P2.xNa
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    NC1=C(N=CN2[C@@]3([H])[C@@](O)([H])[C@@](O)([H])[C@@](O3)([H])COP(O)(OP(O)(O)=O)=O)C2=NC=N1.[x].[Na]
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    -20°C, sealed storage, away from moisture and light

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

    Solvent & Solubility
    In Vitro: 

    DMSO : 25 mg/mL (ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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    Purity & Documentation

    Purity: 99.83%

    SDS (394 KB)

    COA (253 KB) HNMR (127 KB) RP-HPLC (207 KB) MS (69 KB)

    Handling Instructions (2659 KB)
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    Adenosine 5'-diphosphate sodium salt Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Adenosine 5'-diphosphate20398-34-9Endogenous Metabolitenucleoside diphosphateadenylate cyclaseInhibitorinhibitorinhibit

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