2. Metabolic Enzyme/Protease Cell Cycle/DNA Damage
  3. Endogenous Metabolite DNA/RNA Synthesis
  4. Orotidine 5′-monophosphate trisodium

Orotidine 5′-monophosphate (trisodium)  (Synonyms: Orotidine monophosphate (trisodium); Orotidylic acid (trisodium))

製品番号: HY-N8060A 純度: 99.0%
COA 取扱説明書 Technical Support

Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT).

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Orotidine 5′-monophosphate trisodium

Orotidine 5′-monophosphate (trisodium) 構造式

CAS 番号 : 68244-58-6

容量 価格（税別） 在庫状況 数量
1 mg $450 在庫あり
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10 mg   お問い合わせ  

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Based on 1 publication(s) in Google Scholar

Other Forms of Orotidine 5′-monophosphate trisodium:

Orotidine 5′-monophosphate (trisodium) 関連抗体

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Human Endogenous Metabolite Microbial Metabolite

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RNASE L DNA Polymerases RNA Polymerases Helicases DNA Ligase

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製品説明

Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT)[1].

IC50 & Target

Human Endogenous Metabolite

 

分子量

434.14

分子式

C10H10N2Na3O11P
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(N([C@H]1[C@@H]([C@@H]([C@@H](COP(O[Na])(O[Na])=O)O1)O)O)C2=O)=CC(N2)=O)O[Na]
Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外: 

H2O : 50 mg/mL (115.17 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3034 mL 11.5170 mL 23.0340 mL
5 mM 0.4607 mL 2.3034 mL 4.6068 mL
10 mM 0.2303 mL 1.1517 mL 2.3034 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
純度とドキュメンテーション

純度: 99.86%

COA (258 KB) RP-HPLC (212 KB) MS (184 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.3034 mL 11.5170 mL 23.0340 mL 57.5851 mL
5 mM 0.4607 mL 2.3034 mL 4.6068 mL 11.5170 mL
10 mM 0.2303 mL 1.1517 mL 2.3034 mL 5.7585 mL
15 mM 0.1536 mL 0.7678 mL 1.5356 mL 3.8390 mL
20 mM 0.1152 mL 0.5759 mL 1.1517 mL 2.8793 mL
25 mM 0.0921 mL 0.4607 mL 0.9214 mL 2.3034 mL
30 mM 0.0768 mL 0.3839 mL 0.7678 mL 1.9195 mL
40 mM 0.0576 mL 0.2879 mL 0.5759 mL 1.4396 mL
50 mM 0.0461 mL 0.2303 mL 0.4607 mL 1.1517 mL
60 mM 0.0384 mL 0.1920 mL 0.3839 mL 0.9598 mL
80 mM 0.0288 mL 0.1440 mL 0.2879 mL 0.7198 mL
100 mM 0.0230 mL 0.1152 mL 0.2303 mL 0.5759 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Orotidine 5′-monophosphate trisodium Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Orotidine 5′-monophosphate trisodium68244-58-6Orotidine monophosphate trisodium Orotidylic acid trisodiumEndogenous MetaboliteDNA/RNA Synthesispyrimidine nucleotideDNAmicroorganismphosphoribosyl pyrophosphateorotic acidorotate phosphoribosyltransferaseInhibitorinhibitorinhibit

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製品名:
Orotidine 5′-monophosphate trisodium
製品番号:
HY-N8060A
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