Orotidine 5′-monophosphate trisodium
Based on 2 publication(s) in Google Scholar
Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT).
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 68244-58-6
- Formula: C10H10N2Na3O11P
- Molecular Weight:434.14
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Orotidine 5′-monophosphate trisodium
MoreAll Endogenous Metabolite Isoforms
MoreAll DNA/RNA Synthesis Isoforms
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Biological Activity
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Human Endogenous Metabolite |
Chemical Information
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CAS No. 68244-58-6
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Appearance Solid
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Molecular Weight 434.14
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Formula C10H10N2Na3O11P
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Color White to off-white
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SMILES
O=C(C(N([C@H]1[C@@H]([C@@H]([C@@H](COP(O[Na])(O[Na])=O)O1)O)O)C2=O)=CC(N2)=O)O[Na]
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Synonyms
Orotidine monophosphate trisodium; Orotidylic acid trisodium
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (2)
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Journal Impact Factor
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Most Recent
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J Adv Res
Antimycin A inhibits alpha-herpesvirus replication by disrupting the formation of pyrimidinosomes. [Abstract]2025 May 10:S2090-1232(25)00309-1. PMID: 40354935 -
Solvent & Solubility
H2O : 50 mg/mL (115.17 mM; Need ultrasonic and warming)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.3034 mL | 11.5170 mL | 23.0340 mL | 57.5851 mL |
| 5 mM | 0.4607 mL | 2.3034 mL | 4.6068 mL | 11.5170 mL | |
| 10 mM | 0.2303 mL | 1.1517 mL | 2.3034 mL | 5.7585 mL | |
| 15 mM | 0.1536 mL | 0.7678 mL | 1.5356 mL | 3.8390 mL | |
| 20 mM | 0.1152 mL | 0.5759 mL | 1.1517 mL | 2.8793 mL | |
| 25 mM | 0.0921 mL | 0.4607 mL | 0.9214 mL | 2.3034 mL | |
| 30 mM | 0.0768 mL | 0.3839 mL | 0.7678 mL | 1.9195 mL | |
| 40 mM | 0.0576 mL | 0.2879 mL | 0.5759 mL | 1.4396 mL | |
| 50 mM | 0.0461 mL | 0.2303 mL | 0.4607 mL | 1.1517 mL | |
| 60 mM | 0.0384 mL | 0.1920 mL | 0.3839 mL | 0.9598 mL | |
| 80 mM | 0.0288 mL | 0.1440 mL | 0.2879 mL | 0.7198 mL | |
| 100 mM | 0.0230 mL | 0.1152 mL | 0.2303 mL | 0.5759 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.