68244-58-6
Chemical Structure
Orotidine 5′-monophosphate trisodium
Synonym(s): Orotidine monophosphate trisodium; Orotidylic acid trisodium
- CAS. Nr.: 68244-58-6
- Formula:C10H10N2Na3O11P
- Molecular Weight:434.14
IUPAC Name: sodium 3-((2R,3R,4S,5R)-3,4-dihydroxy-5-((phosphonatooxy)methyl)tetrahydrofuran-2-yl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate
InChIKey: IESMRAGOMHGJFC-LLWADOMFSA-K
SMILES: O=C(C(N([C@H]1[C@@H]([C@@H]([C@@H](COP(O[Na])(O[Na])=O)O1)O)O)C2=O)=CC(N2)=O)O[Na]
Biological Activity: Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT)[1].
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Orotidine 5′-monophosphate trisodium | 99.0% | Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT). | ||||||||||||||||||||
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Keywords
