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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
quinoxaline compound
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "quinoxaline compound" in MCE Product Catalog:
67
67 Publications Verification
Synonyms: AKTi-1/2
Research Areas:
AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively.
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AZ3391 is a potent inhibitor of PARP. AZ3391 is a quinoxaline derivative. PARP family of enzymes play an important role in a number of cellular processes, such as replication, recombination, chromatin remodeling, and DNA damage repair. AZ3391 has the potential for the research of diseases and conditions occurring in tissues in the central nervous system, such as the brain and spinal cord (extracted from patent WO2021260092A1, compound 23) .
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2,3-Di(furan-2-yl)quinoxaline (Compound 5) is a quinoxaline exhibiting blue fluorescence. 2,3-Di(furan-2-yl)quinoxaline is cell permeable and sufficiently bright at a micromolar concentration (1.5 μM) .
Cat. No.: HY-W010865
CAS No.: 67174-25-8
Cat. No.: HY-W017519
CAS No.: 1196-57-2
Synonyms: Quinoxalin-2-one
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2-Quinoxalinol (2-hydroxyquinoxaline) is a 2-hydroxylated quinoxaline that possesses photocatalytic activity and interacts with various compounds, such as antioxidant vitamins and aromatic metabolites, including neurotransmitters and the pineal hormone melatonin .
Cat. No.: HY-77982
CAS No.: 164329-39-9
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Ethyl 1,8-dimethyl-4-oxo-4,5-dihydroimidazo[1,2-a]quinoxaline-2-carboxylate is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-20012
CAS No.: 230615-70-0
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8-(Trifluoroacetyl)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline is a drug intermediate for synthesis of various active compounds.
Cat. No.: HY-117725
CAS No.: 146739-86-8
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S-2720 is a potent inhibitor of both immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) and HIV-1 replication. The binding sites of S-2720 and the nonnucleoside compounds overlap. The small pocket in the p66 subunit-BI-RG-587 (HY-10570) complex is most likely the target of S-2720. S-2720 is a quinoxaline derivative, which is promising for research of HIV-1 infection .
Cat. No.: HY-W018677S
CAS No.: 64252-08-0
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Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound .
Cat. No.: HY-B1340S
CAS No.: 1185240-06-5
Cat. No.: HY-136428R
CAS No.: 55456-55-8
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Desoxycarbadox (Standard) is the analytical standard of Desoxycarbadox. This product is intended for research and analytical applications. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound .
Cat. No.: HY-W017519R
CAS No.: 1196-57-2
Synonyms: Quinoxalin-2-one (Standard)
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2-Quinoxalinol (2-hydroxyquinoxaline) is a 2-hydroxylated quinoxaline that possesses photocatalytic activity and interacts with various compounds, such as antioxidant vitamins and aromatic metabolites, including neurotransmitters and the pineal hormone melatonin .
Cat. No.: HY-138806
CAS No.: 943902-10-1
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PAQ (Compound 4c) is a quinoxaline derivative. PAQ is an orally active neuroprotective agent, which targets dopamine (DA) neurons and activates reticulum endoplasmic ryanodine receptor (RyR) channels, without effects on glia cells .
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Cat. No.: HY-162380
CAS No.: 2382959-65-9
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Topoisomerase II inhibitor 18 (Compound IV) is a Quinoxaline derivative, which inhibits topoisomerase II with IC50 of 7.5 μM. Topoisomerase II inhibitor 18 inhibits proliferation, cell cycle at S phase and induces apoptosis in PC-3 cells. Topoisomerase II inhibitor 18 reveals antitumor activity against cancer .
Cat. No.: HY-151292
CAS No.: 2827065-28-9
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Antitumor agent-74 (compound 13da) is a quinoxalines derivative, an antitumor agent. Antitumor agent-74 exhibits more potent efficacy on tumor inhibition, mixed with regioisomer Antitumor agent-75(HY-151295, compound 14 da) (mriBIQ 13da/14da). mriBIQ 13da/14da attests cell cycle at S phase, inhibits DNA synthesis, and induces mithochondrial apoptosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
