2. Search Result
Search Result
Results for "

quinoxaline compound

" in MedChemExpress (MCE) Product Catalog:

24

Inhibitors & Agonists

1

Biochemical Assay Reagents

2

Natural
Products

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10355
    AKT inhibitor VIII
    Maximum Cited Publications
    60 Publications Verification

    AKTi-1/2

    		 Akt Apoptosis Metabolic Disease Cancer
    AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively.
    AKT inhibitor VIII
  • HY-B1340
    Carbadox
    1 Publications Verification

    		 Bacterial Antibiotic Endogenous Metabolite Infection
    Carbadox is a quinoxaline-di-N-oxide antibiotic compound which is widely fed to nursery-age pigs to control enteric diseases and improve feed efficiency.
    Carbadox
  • HY-144874
    AZ3391

    		PARP Neurological Disease Cancer
    AZ3391 is a potent inhibitor of PARP. AZ3391 is a quinoxaline derivative. PARP family of enzymes play an important role in a number of cellular processes, such as replication, recombination, chromatin remodeling, and DNA damage repair. AZ3391 has the potential for the research of diseases and conditions occurring in tissues in the central nervous system, such as the brain and spinal cord (extracted from patent WO2021260092A1, compound 23) .
    AZ3391
  • HY-153349
    2,3-Di(furan-2-yl)quinoxaline

    		Fluorescent Dye Others
    2,3-Di(furan-2-yl)quinoxaline (Compound 5) is a quinoxaline exhibiting blue fluorescence. 2,3-Di(furan-2-yl)quinoxaline is cell permeable and sufficiently bright at a micromolar concentration (1.5 μM) .
    2,3-Di(furan-2-yl)quinoxaline
  • HY-W010865
    N-Benzylquinine chloride

    		Biochemical Assay Reagents Others
    N-Benzylquinine (chloride) is an organic compound. N-Benzylquinine is a derivative of quinoxalines with benzyl substituents. N-Benzylquinine salts are beneficial for the production of tetrahydrofuran trans epoxides .
    N-Benzylquinine chloride
  • HY-W017519
    2-Quinoxalinol

    Quinoxalin-2-one

    		 Drug Intermediate Others
    2-Quinoxalinol (2-hydroxyquinoxaline) is a 2-hydroxylated quinoxaline that possesses photocatalytic activity and interacts with various compounds, such as antioxidant vitamins and aromatic metabolites, including neurotransmitters and the pineal hormone melatonin .
    2-Quinoxalinol
  • HY-77982
    Ethyl 1,8-dimethyl-4-oxo-4,5-dihydroimidazo[1,2-a]quinoxaline-2-carboxylate

    		Drug Intermediate Others
    Ethyl 1,8-dimethyl-4-oxo-4,5-dihydroimidazo[1,2-a]quinoxaline-2-carboxylate is a drug intermediate for synthesis of various active compounds.
    Ethyl 1,8-dimethyl-4-oxo-4,5-dihydroimidazo[1,2-a]quinoxaline-2-carboxylate
  • HY-20012
    8-(Trifluoroacetyl)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline

    		Drug Intermediate Others
    8-(Trifluoroacetyl)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline is a drug intermediate for synthesis of various active compounds.
    8-(Trifluoroacetyl)-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline
  • HY-123354
    SC 44914

    		Bacterial Infection
    SC 44914 is a quinoxaline compound with antibacterial effects. SC-44914 has activity against Campylobacter jejuni, C. coli, and Clostridium difficile .
    SC 44914
  • HY-117725
    S-2720

    		HIV Reverse Transcriptase Infection
    S-2720 is a potent inhibitor of both immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) and HIV-1 replication. The binding sites of S-2720 and the nonnucleoside compounds overlap. The small pocket in the p66 subunit-BI-RG-587 (HY-10570) complex is most likely the target of S-2720. S-2720 is a quinoxaline derivative, which is promising for research of HIV-1 infection .
    S-2720
  • HY-W018677S
    Quinoxaline-d4

    		Antibiotic Infection
    Quinoxaline-d4 is the deuterium labeled Quinoxaline . Quinoxaline is a chemical compound that acts as an intermediate for anti-tuberculosis agent Pyrazinamide. Quinoxaline presents a structure that is similar to quinolone antibiotics .
    Quinoxaline-d4
  • HY-136428
    Desoxycarbadox

    		Drug Metabolite Cancer
    Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound .
    Desoxycarbadox
  • HY-136428S
    Desoxycarbadox-d3
    1 Publications Verification

    		 Isotope-Labeled Compounds Cancer
    Desoxycarbadox-d3 is the deuterium labeled Desoxycarbadox. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound.
    Desoxycarbadox-d3
  • HY-B1340S
    Carbadox-d3

    		Bacterial Antibiotic Endogenous Metabolite Infection
    Carbadox-d3 is the deuterium labeled Carbadox. Carbadox is a quinoxaline-di-N-oxide antibiotic compound which is widely fed to nursery-age pigs to control enteric diseases and improve feed efficiency.
    Carbadox-d3
  • HY-136428R
    Desoxycarbadox (Standard)

    		Drug Metabolite Antibiotic Reference Standards Cancer
    Desoxycarbadox (Standard) is the analytical standard of Desoxycarbadox. This product is intended for research and analytical applications. Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound .
    Desoxycarbadox (Standard)
  • HY-W017519R
    2-Quinoxalinol (Standard)

    Quinoxalin-2-one (Standard)

    		 Drug Intermediate Reference Standards Others
    2-Quinoxalinol (2-hydroxyquinoxaline) is a 2-hydroxylated quinoxaline that possesses photocatalytic activity and interacts with various compounds, such as antioxidant vitamins and aromatic metabolites, including neurotransmitters and the pineal hormone melatonin .
    2-Quinoxalinol (Standard)
  • HY-138806
    PAQ

    		Calcium Channel Neurological Disease
    PAQ (Compound 4c) is a quinoxaline derivative. PAQ is an orally active neuroprotective agent, which targets dopamine (DA) neurons and activates reticulum endoplasmic ryanodine receptor (RyR) channels, without effects on glia cells .
    PAQ
  • HY-B1340R
    Carbadox (Standard)

    		Reference Standards Bacterial Antibiotic Endogenous Metabolite Infection
    Carbadox (Standard) is the analytical standard of Carbadox. This product is intended for research and analytical applications. Carbadox is a quinoxaline-di-N-oxide antibiotic compound which is widely fed to nursery-age pigs to control enteric diseases and improve feed efficiency.
    Carbadox (Standard)
  • HY-162380
    Topoisomerase II inhibitor 18

    		Topoisomerase Cancer
    Topoisomerase II inhibitor 18 (Compound IV) is a Quinoxaline derivative, which inhibits topoisomerase II with IC50 of 7.5 μM. Topoisomerase II inhibitor 18 inhibits proliferation, cell cycle at S phase and induces apoptosis in PC-3 cells. Topoisomerase II inhibitor 18 reveals antitumor activity against cancer .
    Topoisomerase II inhibitor 18
  • HY-151292
    Antitumor agent-74

    		DNA/RNA Synthesis Cancer
    Antitumor agent-74 (compound 13da) is a quinoxalines derivative, an antitumor agent. Antitumor agent-74 exhibits more potent efficacy on tumor inhibition, mixed with regioisomer Antitumor agent-75(HY-151295, compound 14 da) (mriBIQ 13da/14da). mriBIQ 13da/14da attests cell cycle at S phase, inhibits DNA synthesis, and induces mithochondrial apoptosis .
    Antitumor agent-74
  • HY-W779191
    MeIQx-13C

    2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2-13C

    		 Isotope-Labeled Compounds Cytochrome P450 Cancer
    MeIQx- 13C (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-2- 13C) is the 13C-labeled MeIQx (HY-W355129). MeIQx, a dietary aromatic amine, is mutagenic compound could be isolated from present in fried beef and beef extracts. MeIQx binds covalently to hemoglobin. MeIQx induces liver tumors .
    MeIQx-13C
  • HY-180767
    Azithromycin-amide-C3-amide-quinoxaline

    		Drug Derivative Bacterial Topoisomerase Infection Cancer
    Azithromycin-amide-C3-amide-quinoxaline (Compound 5f) is an Azithromycin (HY-17506) derivative and antibacterial agent. Azithromycin-amide-C3-amide-quinoxaline inhibits topoisoisomerase I with an IC50 of 120.7 μM. Azithromycin-amide-C3-amide-quinoxaline interacts with 70S E. coli ribosome with a Kd of 0.8 nM. Azithromycin-amide-C3-amide-quinoxaline inhibits bacterial translation with an IC50 of 0.7 μM. Azithromycin-amide-C3-amide-quinoxaline shows antibacterial potency against S. pneumonia ATCC 49619, S. aureus ATCC 29213, E. faecalis ATCC 29212 with MICs of 0.06 μg/mL, 2 μg/mL, 0.5 μg/mL, respectively. Azithromycin-amide-C3-amide-quinoxaline exhibits anticancer activity against prostate cancer, colon cancer .
    Azithromycin-amide-C3-amide-quinoxaline
  • HY-23695
    4-Chloro-7-fluoropyrrolo[1,2-a]quinoxaline

    		Drug Intermediate Others
    4-Chloro-7-fluoropyrrolo[1,2-a]quinoxaline is a drug intermediate for synthesis of various active compounds.
    4-Chloro-7-fluoropyrrolo[1,2-a]quinoxaline
  • HY-10355R
    AKT inhibitor VIII (Standard)

    AKTi-1/2 (Standard)

    		 Reference Standards Akt Apoptosis Metabolic Disease Cancer
    AKT inhibitor VIII (Standard) is the analytical standard of AKT inhibitor VIII (HY-10355). This product is intended for research and analytical applications. AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively.
    AKT inhibitor VIII (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: