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sympathomimetic effects

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (9) Drug Metabolite (1) Monoamine Oxidase (1) Reference Standards (2) Serotonin Transporter (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (10) Endocrinology (3) Inflammation/Immunology (2) Neurological Disease (7)

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Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1231

Heptaminol hydrochloride RP-2831 hydrochloride	Adrenergic Receptor	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels .

HY-100634

4-Hydroxypropranolol hydrochloride (±)-4-hydroxy Propranolol hydrochloride	Adrenergic Receptor	Cardiovascular Disease
4-Hydroxypropranolol hydrochloride is a non-cardiac selective β-adrenergic receptor antagonist and a metabolite produced after oral administration of Propranolol (HY-B0573B). 4-Hydroxypropranolol hydrochloride also acts as a membrane stabilizer and possesses intrinsic sympathomimetic inhibitory activity. 4-Hydroxypropranolol hydrochloride blocks β-adrenergic receptors to antagonize the effects of catecholamines, acts as a partial β-adrenergic receptor agonist, and induces membrane stabilization. 4-Hydroxypropranolol hydrochloride alters heart rate, left ventricular contractility, and atrioventricular conduction time. 4-Hydroxypropranolol hydrochloride can be used in research related to cardiovascular and cerebrovascular diseases .

HY-17447

Tranylcypromine SKF 385	Monoamine Oxidase	Cardiovascular Disease Endocrinology Cancer
Tranylcypromine (SKF 385) is a potent monoamine oxidase (MAO) inhibitor .

HY-Z6449

Phenylephrone hydrochloride	Adrenergic Receptor	Neurological Disease
Phenylephrine hydrochlorid is an α1-adrenergic receptor agonist. As a sympathomimetic agent, Phenylephrine hydrochlorid exerts similar effects to epinephrine and ephedrine. Phenylephrine hydrochlorid induces vasoconstriction and increases perfusion pressure .

HY-B1116

Metaraminol tartrate Metaradrine tartrate	Adrenergic Receptor	Cardiovascular Disease Endocrinology
Metaraminol tartrate?(Metaradrine tartrate) is an α-adrenergic agonist . Metaraminol tartrate is a sympathomimetic amine that directly and indirectly affects adrenergic receptors, with alpha effects being predominant.Metaraminol tartrate acts as a vasopressor agent .

HY-121609A

Pholedrine hydrochloride	Drug Metabolite	Cardiovascular Disease
Pholedrine hydrochloride, the main metabolite of methamphetamine, is an indirectly acting sympathomimetic amine. Pholedrine hydrochloride is a cardiovascular agent exerting hypertensive and adrenergic effects. Pholedrine hydrochloride can produce mydriatic response and allow localization of the site of the interruption in the oculosympathetic pathway. Pholedrine hydrochloride can be used as a topical eye drop and a diagnostic agent for use in Horner's syndrome .

HY-A0022

Azaphen Azafen; Pipofezin hydrochloride; Pipofezine hydrochloride	Serotonin Transporter	Neurological Disease
Azaphen (Pipofezin) is an orally active serotonin reuptake inhibitor. Azaphen potentiates sympathomimetic compound effects. Azaphen can be used for the research of depressive states .

HY-A0022A

Azaphen dihydrochloride monohydrate 1 Publications Verification Azafen dihydrochloride monohydrate; Pipofezin dihydrochloride monohydrate; Pipofezine dihydrochloride monohydrate; Azaphenonxazine dihydrochloride monohydrate	Serotonin Transporter	Neurological Disease
Azaphen (Pipofezin) dihydrochloride monohydrate is an orally active serotonin reuptake inhibitor. Azaphen dihydrochloride monohydrate potentiates sympathomimetic compound effects. Azaphen dihydrochloride monohydrate can be used for the research of depressive states .

HY-N15338

Phyllalbine	Others	Neurological Disease
Phyllalbine is an alkaloid compound found in the roots of Convolvulus subhirsutus, exhibiting both central and peripheral sympathomimetic effects, making it a promising candidate for neurological disease research .

HY-B1116R

Metaraminol tartrate (Standard) Metaradrine tartrate (Standard)	Reference Standards Adrenergic Receptor	Cardiovascular Disease Endocrinology
Metaraminol (tartrate) (Standard) is the analytical standard of Metaraminol (tartrate). This product is intended for research and analytical applications. Metaraminol tartrate?(Metaradrine tartrate) is an α-adrenergic agonist . Metaraminol tartrate is a sympathomimetic amine that directly and indirectly affects adrenergic receptors, with alpha effects being predominant.Metaraminol tartrate acts as a vasopressor agent .

HY-121609

Pholedrine	Adrenergic Receptor	Cardiovascular Disease Neurological Disease
Pholedrine, the main metabolite of methamphetamine, is an indirectly acting sympathomimetic amine. Pholedrine is a cardiovascular agent exerting hypertensive and adrenergic effects. Pholedrine can produce mydriatic response and allow localization of the site of the interruption in the oculosympathetic pathway. Pholedrine can be used as a topical eye drop and a diagnostic agent for use in Horner's syndrome .

HY-106684

Ridazolol	Adrenergic Receptor	Cardiovascular Disease
Ridazolol is a β-adrenergic receptor (βAR) antagonist. Ridazolol exhibits a high degree of selectivity for β-1 adrenergic receptor (β1AR) and possesses moderate intrinsic sympathomimetic activity (ISA). Ridazolol can competitively antagonize the relaxation effects induced by isoproterenol. Ridazolol is utilized in the research of cardiovascular diseases .

HY-B1231R

Heptaminol hydrochloride (Standard) RP-2831 hydrochloride (Standard)	Adrenergic Receptor Reference Standards	Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Heptaminol (hydrochloride) (Standard) is the analytical standard of Heptaminol (hydrochloride). This product is intended for research and analytical applications. Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels .

HY-106684A

Ridazolol hydrochloride	Adrenergic Receptor	Cardiovascular Disease
Ridazolol hydrochloride is a β-adrenergic receptor (βAR) antagonist. Ridazolol hydrochloride exhibits a high degree of selectivity for β-1 adrenergic receptor (β1AR) and possesses moderate intrinsic sympathomimetic activity (ISA). Ridazolol hydrochloride can competitively antagonize the relaxation effects induced by isoproterenol. Ridazolol hydrochloride is utilized in the research of cardiovascular diseases .

Azaphen Azafen; Pipofezin hydrochloride; Pipofezine hydrochloride	Structural Classification Natural Products Animals Source Classification	Serotonin Transporter
Azaphen (Pipofezin) is an orally active serotonin reuptake inhibitor. Azaphen potentiates sympathomimetic compound effects. Azaphen can be used for the research of depressive states .

Phyllalbine	Alkaloids Convolvulus krauseanus Regel & Schmalh. Quinoline Alkaloids Plants Convolvulaceae Source Classification	Others
Phyllalbine is an alkaloid compound found in the roots of Convolvulus subhirsutus, exhibiting both central and peripheral sympathomimetic effects, making it a promising candidate for neurological disease research .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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sympathomimetic effects

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