1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. 4-Hydroxypropranolol hydrochloride

4-Hydroxypropranolol hydrochloride (Synonyms: (±)-4-hydroxy Propranolol hydrochloride)

Cat. No.: HY-100634
Handling Instructions

4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties.

For research use only. We do not sell to patients.

4-Hydroxypropranolol hydrochloride Chemical Structure

4-Hydroxypropranolol hydrochloride Chemical Structure

CAS No. : 14133-90-5

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Description

4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3].

IC50 & Target

pA2: 8.24 (β1-adrenergic receptor) and 8.26 (β2-adrenergic receptor)[2]

Molecular Weight

311.80

Formula

C₁₆H₂₂ClNO₃

CAS No.

14133-90-5

SMILES

OC1=C2C=CC=CC2=C(OCC(O)CNC(C)C)C=C1.Cl[H]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

4-Hydroxypropranolol(±)-4-hydroxy PropranololAdrenergic ReceptorBeta Receptorβ1-adrenergicβ2-adrenergicreceptorsintrinsicsympathomimeticmembranestabilizingantioxidantInhibitorinhibitorinhibit

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Product Name:
4-Hydroxypropranolol hydrochloride
Cat. No.:
HY-100634
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