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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
testicular toxicity
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "testicular toxicity" in MCE Product Catalog:
5
5 Cited Publications
Cat. No.: HY-B1066
CAS No.: 25013-16-5
Synonyms: Butylated hydroxyanisole; E320
Research Areas:
Butylhydroxyanisole (Butylated hydroxyanisole) is an antioxidant used as a food additive preservative. Butylhydroxyanisole mediates liver toxicity, retardation in reproductive organ development and learning, and sleep deficit. Butylhydroxyanisole exerts neurotoxic effects and leads to disruption of the brain and nerve development . Butylhydroxyanisole is a ferroptosis inducer .
5
Target:
Synonyms: Perfluoroheptanoic acid; Tridecafluoroheptanoic acid; PFHpA
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology
Perfluoroenanthic acid (Perfluoroheptanoic acid) is a kind of perfluoroalkyl carboxylic acid organic pollutant. Perfluoroenanthic acid has environmental persistence and bioaccumulation, and exposure can occur via oral, dermal and other routes. Perfluoroenanthic acid exhibits reproductive toxicity, neurotoxicity, hepatotoxicity, immunotoxicity and endocrine-disrupting effects. Perfluoroenanthic acid exerts definite adverse effects on development, spermatogenesis, neuronal activity and liver tissue .
Target:
Cat. No.: HY-W585827
CAS No.: 497-04-1
Synonyms: 2-MCPD
Target:
Research Areas:
2-Chloro-1,3-propanediol (2-MCPD) is a pharmaceutical intermediate. 2-Chloro-1,3-propanediol is a common glycerol-derived chemical intermediate and also a food processing contaminant. 2-Chloro-1,3-propanediol can cross the intestinal barrier model via paracellular diffusion. 2-Chloro-1,3-propanediol induces renal and testicular toxicity in animal models. 2-Chloro-1,3-propanediol can be used in research related to organic synthesis .
Cat. No.: HY-W585827S
CAS No.: 1216764-05-4
Synonyms: 2-MCPD-d5
Cat. No.: HY-W585827S1
CAS No.: 1216764-05-4
Synonyms: 2-MCPD-d5 (major)
Cat. No.: HY-130071
CAS No.: 62928-11-4
Synonyms: CHIP
Target:
Research Areas:
Iproplatin (CHIP) is an anti-cancer agent with reduced toxicity in testicular and ovarian cancers. The major reduced product of Iproplatin by glutathione is chloro-bis (isopropylamine) glutathionatoplatinum (II). Iproplatin is promising for research of Thrombocytopenia and a wide range of cancers .
Cat. No.: HY-Y1009S
CAS No.: 345910-00-1
Cat. No.: HY-W275882
CAS No.: 13179-98-1
Target:
Research Areas:
1,6-Dimethoxyhexane is an aliphatic ether that serves as a PROTAC linker and fuel additive. 1,6-Dimethoxyhexane is an orally active testicular toxicant. It has no direct toxicity on its own, but exerts toxicity after oxidative metabolism by liver/testicular microsomes to produce 2-Methoxyacetic Acid (MAA). 1,6-Dimethoxyhexane induces apoptosis/necrosis of pachytene spermatocytes, downregulates the expression of HSP70.2, HSP60 and ERp60/PDI A3, and causes spermatogenic tubule degeneration, testicular/thymic atrophy, a sharp decline in epididymal sperm density, and other effects. 1,6-Dimethoxyhexane can be used in studies related to testicular toxicity .
Research Areas:
Methiocarb (Mercaptodimethur) is an orally active carbamate insecticide. Methiocarb exerts dose-dependent toxic effects on onions. In addition to inhibiting acetylcholinesterase to induce cholinergic excitation, Methiocarb can induce lipid peroxidation in liver, kidney, brain and testicular tissues and alter reduced glutathione levels by generating ROS. Methiocarb can be used for agricultural pest control and research on oxidative stress-related cellular damage in mammals .
Cat. No.: HY-124920S
CAS No.: 1581694-94-1
Synonyms: Mercaptodimethur-d3
Cat. No.: HY-W585827R
CAS No.: 497-04-1
Synonyms: 2-MCPD (Standard)
Target:
Research Areas:
2-Chloro-1,3-propanediol (Standard) (2-MCPD (Standard)) is the analytical standard of 2-Chloro-1,3-propanediol (HY-W585827). This product is intended for research and analytical applications. 2-Chloro-1,3-propanediol (2-MCPD) is a pharmaceutical intermediate. 2-Chloro-1,3-propanediol is a common glycerol-derived chemical intermediate and also a food processing contaminant. 2-Chloro-1,3-propanediol can cross the intestinal barrier model via paracellular diffusion. 2-Chloro-1,3-propanediol induces renal and testicular toxicity in animal models. 2-Chloro-1,3-propanediol can be used in research related to organic synthesis .
Cat. No.: HY-182438
CAS No.: 91456-99-4
Target:
Research Areas:
SDZ 51641 is an orally active fatty acid oxidation inhibitor. By reducing fatty acid oxidation, SDZ 51641 deprives the gluconeogenesis process of required energy and cofactors, thereby lowering blood glucose levels in diabetic models. SDZ 51641 can be used in diabetes research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
