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Results for "

viral Vpr protein

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Peptides

3

Natural
Products

2

Recombinant Proteins

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0751
    Fumagillin
    1 Publications Verification

    Amebacilin; NSC9168

    		 Parasite HIV Antibiotic Infection
    Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
    Fumagillin
  • HY-N2000
    Bellidifolin
    1 Publications Verification

    		 STAT PI3K mTOR Akt Neurological Disease Inflammation/Immunology Cancer
    Bellidifolin is an orally active compound with antiproliferative, anti-inflammatory and antioxidant properties. Bellidifolin modulates key signaling pathways including STAT3, PI3K-Akt, mTOR and BRD4, and inhibits the viral protein R (Vpr). Bellidifolin induces cell cycle arrest and apoptosis, exerts significant antifibrotic effects, and protects the heart, liver and nervous system. Bellidifolin is applicable to the research of various diseases such as lung cancer, non-alcoholic fatty liver disease, myocardial hypertrophy and ischemic cranial nerve injury .
    Bellidifolin
  • HY-175343
    OICR-41103

    		Ligands for E3 Ligase Infection
    OICR-41103 is an effective, selective, cell-active DCAF1 small molecule chemical probe that targets the DCAF1 WDR domain and replaces the viral Vpr protein. The binding Ki value of OICR-41103 and DCAF1 is less than 2 nM .
    OICR-41103
  • HY-B0751R
    Fumagillin (Standard)

    Amebacilin (Standard); NSC9168 (Standard)

    		 Reference Standards Parasite HIV Antibiotic Infection
    Fumagillin (Standard) is the analytical standard of Fumagillin. This product is intended for research and analytical applications. Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
    Fumagillin (Standard)
  • HY-175343A
    OICR-41103N

    		Ligands for E3 Ligase Infection
    OICR-41103N is the negative control form of OICR-41103 (HY-175343). OICR-41103 is an effective, selective, cell-active DCAF1 small molecule chemical probe (Ki<2 nM) that targets the DCAF1 WDR domain and replaces the viral Vpr protein .
    OICR-41103N
  • HY-P11640
    Vpr (1-14)

    		Ligands for E3 Ligase HIV Infection
    Vpr (1-14) is a viral protein R and acts as an accessory protein of HIV-1. Vpr (1-14) can binds to Cul4A-DDB1-DCAF1 E3 ligase complex and can be used as an E3 ligase-binding component in PROTACs. Vpr (1-14) can be used to synthesize PROTAC BRD4 Degrader-43 (HY-181164) .
    Vpr (1-14)
  • HY-B0751S
    Fumagillin-13C26

    Amebacilin-13C26; NSC9168-13C26

    		 Isotope-Labeled Compounds Infection
    Fumagillin- 13C26 (Amebacilin- 13C26) is the 13C-labeled Fumagillin (HY-B0751). Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
    Fumagillin-13C26

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