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  4. Sodium diethylcarbamodithioate trihydrate

Sodium diethylcarbamodithioate trihydrate  (Synonyms: Ditiocarb sodium trihydrate)

製品番号: HY-W009722 純度: 98.0%
COA 取扱説明書 Technical Support

Sodium diethylcarbamodithioate (Ditiocarb sodium) trihydrate is a copper reagent. The reaction with Cu2+ solution resulted in the formation of a complex, which increased the copper displacement precipitation rate. Sodium diethylcarbamodithioate trihydrate can reduce HIV infection and can be used in adjuvant immune research of high-risk breast cancer.

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Sodium diethylcarbamodithioate trihydrate

Sodium diethylcarbamodithioate trihydrate 構造式

CAS 番号 : 20624-25-3

容量 価格（税別） 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 27 在庫あり
Solution
10 mM * 1 mL in DMSO USD 27 在庫あり
Solid
100 mg $25 在庫あり
250 mg $45 在庫あり
500 mg $63 在庫あり
1 g $100 在庫あり
5 g   お問い合わせ  
10 g   お問い合わせ  

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Based on 4 publication(s) in Google Scholar

Other Forms of Sodium diethylcarbamodithioate trihydrate:

Sodium diethylcarbamodithioate trihydrate 関連抗体

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製品説明

Sodium diethylcarbamodithioate (Ditiocarb sodium) trihydrate is a copper reagent. The reaction with Cu2+ solution resulted in the formation of a complex, which increased the copper displacement precipitation rate. Sodium diethylcarbamodithioate trihydrate can reduce HIV infection and can be used in adjuvant immune research of high-risk breast cancer[1][2][3].

体外実験

Sodium diethylcarbamodithioate trihydrate reacts with the Cu2+ solution giving a complex of copper diethyldithiocarbamate, which enhances the rate of cementation[1]. Sodium diethylcarbamodithioate trihydrate is an agent with strong antioxidant capacity and chelating activities[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sodium diethylcarbamodithioate trihydrate 関連抗体
体内実験

Sodium diethylcarbamodithioate trihydrate improves the depressed immune responses of newborn and aged mice. Sodium diethylcarbamodithioate trihydrate prevents cisplatin nephrotoxicity in animals without reducing the antitumor activity. In that AIDS model, Sodium diethylcarbamodithioate trihydrate reduces lymphadenopathy and hypergammaglobulinemia, restores immunocompetence, and prolongs survival[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
臨床実験
分子量

225.31

分子式

C5H16NNaO3S2
CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

CCN(C(S[Na])=S)CC.O.O.O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Store at room temperature, keep dry and cool

*In solvent : -80°C, 6 months; -20°C, 1 month (Store at room temperature, keep dry and cool)
溶剤 & 溶解度
体外: 

DMSO : 200 mg/mL (887.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4383 mL 22.1916 mL 44.3833 mL
5 mM 0.8877 mL 4.4383 mL 8.8767 mL
10 mM 0.4438 mL 2.2192 mL 4.4383 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

体内:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 5 mg/mL (22.19 mM); Clear solution

    This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 5 mg/mL (22.19 mM); Clear solution

    This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
純度とドキュメンテーション

純度: 98.0%

COA (251 KB) HNMR (279 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.4383 mL 22.1916 mL 44.3833 mL 110.9582 mL
5 mM 0.8877 mL 4.4383 mL 8.8767 mL 22.1916 mL
10 mM 0.4438 mL 2.2192 mL 4.4383 mL 11.0958 mL
15 mM 0.2959 mL 1.4794 mL 2.9589 mL 7.3972 mL
20 mM 0.2219 mL 1.1096 mL 2.2192 mL 5.5479 mL
25 mM 0.1775 mL 0.8877 mL 1.7753 mL 4.4383 mL
30 mM 0.1479 mL 0.7397 mL 1.4794 mL 3.6986 mL
40 mM 0.1110 mL 0.5548 mL 1.1096 mL 2.7740 mL
50 mM 0.0888 mL 0.4438 mL 0.8877 mL 2.2192 mL
60 mM 0.0740 mL 0.3699 mL 0.7397 mL 1.8493 mL
80 mM 0.0555 mL 0.2774 mL 0.5548 mL 1.3870 mL
100 mM 0.0444 mL 0.2219 mL 0.4438 mL 1.1096 mL
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Sodium diethylcarbamodithioate trihydrate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sodium diethylcarbamodithioate20624-25-3Ditiocarb sodiumHIVBiochemical Assay ReagentsHuman immunodeficiency virusbiochemical assayreagentInhibitorinhibitorinhibit

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製品名:
Sodium diethylcarbamodithioate trihydrate
製品番号:
HY-W009722
数量:
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