1. Anti-infection
  2. HIV
  3. Ditiocarb sodium

Ditiocarb sodium (Synonyms: Sodium diethyldithiocarbamate)

Cat. No.: HY-B1637 Purity: 98.13%
Handling Instructions

Ditiocarb sodium (Sodium diethyldithiocarbamate) is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV infection.

For research use only. We do not sell to patients.

Ditiocarb sodium Chemical Structure

Ditiocarb sodium Chemical Structure

CAS No. : 148-18-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
500 mg USD 50 In-stock
Estimated Time of Arrival: December 31
1 g USD 60 In-stock
Estimated Time of Arrival: December 31
5 g   Get quote  
10 g   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Ditiocarb sodium (Sodium diethyldithiocarbamate) is an accelerator of the rate of copper cementation. Sodium diethyldithiocarbamate reduces the incidence of HIV infection.

IC50 & Target

HIV[2]

In Vitro

Ditiocarb sodium (Sodium diethyldithiocarbamate) reacts with the Cu2+ solution giving a complex of copper diethyldithiocarbamate, which enhances the rate of cementation[1]. Ditiocarb sodium is an agent with strong antioxidant capacity and chelating activities[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Ditiocarb sodium (Sodium diethyldithiocarbamate) improves the depressed immune responses of newborn and aged mice. Sodium diethyldithiocarbamate prevents cisplatin nephrotoxicity in animals without reducing the antitumor activity. In that AIDS model, Ditiocarb sodium reduces lymphadenopathy and hypergammaglobulinemia, restores immunocompetence, and prolongs survival[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

171.26

Formula

C₅H₁₀NNaS₂

CAS No.
SMILES

[S-]C(N(CC)CC)=S.[Na+]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (583.91 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8391 mL 29.1954 mL 58.3908 mL
5 mM 1.1678 mL 5.8391 mL 11.6782 mL
10 mM 0.5839 mL 2.9195 mL 5.8391 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (14.60 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (14.60 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (14.60 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

DitiocarbSodium diethyldithiocarbamateHIVHuman immunodeficiency virusInhibitorinhibitorinhibit

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Product Name:
Ditiocarb sodium
Cat. No.:
HY-B1637
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