Testosterone sulfate (pyridinium)

Name: Testosterone sulfate (pyridinium)
Brand: MedChemExpress
SKU: HY-113415A
Rating: 4.5 (1 reviews)

製品番号: HY-113415A 純度: 99.70%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

Testosterone sulfate pyridinium is a Testosterone sulfate with a pyridinium. Testosterone sulfate pyridinium is the metabolite of Testosterone. Testosterone is the main male sex hormone which determination is useful for assessment of androgen status.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Testosterone sulfate (pyridinium) 構造式

CAS 番号 : 34991-10-1

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 286	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 286	在庫あり	Estimated Time of Arrival: December 31
Solid
5 mg	$260	在庫あり	Estimated Time of Arrival: December 31
10 mg	$380	在庫あり	Estimated Time of Arrival: December 31
25 mg	$800	在庫あり	Estimated Time of Arrival: December 31
50 mg	$1280	在庫あり	Estimated Time of Arrival: December 31
100 mg	$2100	在庫あり	Estimated Time of Arrival: December 31
200 mg		お問い合わせ
500 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of Testosterone sulfate (pyridinium):

Testosterone sulfate お問い合わせ

顧客検証

•Am J Pathol. 2024 Sep 5:S0002-9440(24)00331-6. [Abstract]

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Human Endogenous Metabolite Microbial Metabolite

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

IC₅₀ & Target

Human Endogenous Metabolite

体外実験

Testosterone sulfate pyridinium is a biomarker for exogenous testosterone intake, however, it needs to undergo hydrolysis (decoupling) to be converted into free testosterone before it can be effectively detected by analytical instruments such as chromatography-mass spectrometry. Enzymatic hydrolysis using an enzyme preparation containing sulfatase is an effective and reliable method for releasing free testosterone for detection^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

447.59

分子式

C₂₄H₃₃NO₅S

CAS 番号

34991-10-1

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)OS(=O)(O)=O)C.C5=CC=NC=C5

Structure Classification

Steroids

Initial Source

Endogenous metabolite

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (223.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.2342 mL	11.1709 mL	22.3419 mL
5 mM	0.4468 mL	2.2342 mL	4.4684 mL
10 mM	0.2234 mL	1.1171 mL	2.2342 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

体内:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (5.59 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (5.59 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (5.59 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

純度とドキュメンテーション

純度: 99.89%

Select Batch:

データシート (275 KB) SDS (251 KB)

COA (250 KB) HNMR (142 KB) LCMS (88 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Pizzato EC, Filonzi M, Rosa HSD, de Bairros AV. Pretreatment of different biological matrices for exogenous testosterone analysis: a review. Toxicol Mech Methods. 2017;27(9):641-656. [Content Brief]

[2]. Mroczko B, et al. Niektóre problemy zwiazane z oznaczaniem testosteronu [Some problems with testosterone determination]. Endokrynol Pol. 2007;58(5):440-445. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.2342 mL	11.1709 mL	22.3419 mL	55.8547 mL
	5 mM	0.4468 mL	2.2342 mL	4.4684 mL	11.1709 mL
	10 mM	0.2234 mL	1.1171 mL	2.2342 mL	5.5855 mL
	15 mM	0.1489 mL	0.7447 mL	1.4895 mL	3.7236 mL
	20 mM	0.1117 mL	0.5585 mL	1.1171 mL	2.7927 mL
	25 mM	0.0894 mL	0.4468 mL	0.8937 mL	2.2342 mL
	30 mM	0.0745 mL	0.3724 mL	0.7447 mL	1.8618 mL
	40 mM	0.0559 mL	0.2793 mL	0.5585 mL	1.3964 mL
	50 mM	0.0447 mL	0.2234 mL	0.4468 mL	1.1171 mL
	60 mM	0.0372 mL	0.1862 mL	0.3724 mL	0.9309 mL
	80 mM	0.0279 mL	0.1396 mL	0.2793 mL	0.6982 mL
	100 mM	0.0223 mL	0.1117 mL	0.2234 mL	0.5585 mL