1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. WRN inhibitor 7

WRN inhibitor 7 (Compound h6) is a WRN inhibitor. WRN inhibitor 7 effectively inhibits WRN's helicase and ATPase activity (IC50: 9.8 μM and 15.8 μM respectively). WRN inhibitor 7 can be used for research of microsatellite instable (MSI) cancers.

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WRN inhibitor 7

WRN inhibitor 7 Estructura química

No. CAS : 444780-45-4

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Descripciòn

WRN inhibitor 7 (Compound h6) is a WRN inhibitor. WRN inhibitor 7 effectively inhibits WRN's helicase and ATPase activity (IC50: 9.8 μM and 15.8 μM respectively). WRN inhibitor 7 can be used for research of microsatellite instable (MSI) cancers[1].

IC50 & Target

Helicase

 

Peso molecular

485.49

Fòrmula

C27H23N3O6

No. CAS
SMILES

O=C(N/1)N(CC(NC2=CC=C(C)C=C2)=O)C(C1=C/C3=C(OCC4=CC(C(O)=O)=CC=C4)C=CC=C3)=O

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Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
WRN inhibitor 7
Cat. No.:
HY-161386
Cantidad:
MCE Japan Authorized Agent: