2,3-Diaminopropionic acid hydrochloride

Name: 2,3-Diaminopropionic acid hydrochloride
Brand: MedChemExpress
SKU: HY-W013673
Rating: 4.5 (0 reviews)

Cat. No.: HY-W013673 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
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Technical Support

2,3-Diaminopropionic acid hydrochloride is the precursor of antibiotics and the siderophore staphyloferrin B. 2,3-Diaminopropionic acid hydrochloride is the inhibitor for polyphenoloxidase (PPO).

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2,3-Diaminopropionic acid hydrochloride 화학구조

CAS No. : 1482-97-9

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	해외재고보유	Estimated Time of Arrival: December 31
Solid
100 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	해외재고보유	Estimated Time of Arrival: December 31
5 g	견적 받기
10 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of 2,3-Diaminopropionic acid hydrochloride:

2,3-Diaminopropionic acid 견적 받기
2,3-Diaminopropionic acid hydrochloride (Standard) 견적 받기

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•Related Screening Libraries:

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

2,3-Diaminopropionic acid hydrochloride is the precursor of antibiotics and the siderophore staphyloferrin B. 2,3-Diaminopropionic acid hydrochloride is the inhibitor for polyphenoloxidase (PPO)^[1]^[2].

IC₅₀ & Target

Human Endogenous Metabolite

In Vitro

2,3-Diaminopropionic acid hydrochloride inhibits the activity of PPO in mushrooms, artichokes, and basil, and prevents the enzymatic browning of fruits and vegetables^[2].
2,3-Diaminopropionic acid hydrochloride scavenges the α-dicarbonyl compound, and prevents the formation of advanced glycation endproducts (AGEs)^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

140.57

화학식

C₃H₉ClN₂O₂

CAS No.

1482-97-9

Appearance

Solid

Color

White to off-white

SMILES

N[C@@H](CN)C(O)=O.Cl

Structure Classification

Others

Initial Source

Endogenous metabolite

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

H₂O : 66.67 mg/mL (474.28 mM; ultrasonic and warming and adjust pH to 2 with 1 M HCl and heat to 60°C)

1 M HCl : 50 mg/mL (355.69 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.1139 mL	35.5695 mL	71.1389 mL
5 mM	1.4228 mL	7.1139 mL	14.2278 mL
10 mM	0.7114 mL	3.5569 mL	7.1139 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 25 mg/mL (177.85 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: ≥98.0%

Select Batch:

Data Sheet (273 KB) SDS (394 KB)

COA (248 KB)

Handling Instructions (2659 KB)

References

[1]. Kobylarz MJ, et al., Synthesis of L-2,3-diaminopropionic acid, a siderophore and antibiotic precursor. Chem Biol. 2014 Mar 20;21(3):379-88. [Content Brief]

[2]. Arslan O, et al., Inhibition of polyphenol oxidase obtained from various sources by 2, 3‐diaminopropionic acid[J]. Journal of the Science of Food and Agriculture, 2005, 85(9): 1499-1504.

[3]. Sasaki NA, et al., N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation. Bioorg Med Chem. 2009 Mar 15;17(6):2310-20. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

1 M HCl / H₂O	1 mM	7.1139 mL	35.5695 mL	71.1389 mL	177.8473 mL
	5 mM	1.4228 mL	7.1139 mL	14.2278 mL	35.5695 mL
	10 mM	0.7114 mL	3.5569 mL	7.1139 mL	17.7847 mL
	15 mM	0.4743 mL	2.3713 mL	4.7426 mL	11.8565 mL
	20 mM	0.3557 mL	1.7785 mL	3.5569 mL	8.8924 mL
	25 mM	0.2846 mL	1.4228 mL	2.8456 mL	7.1139 mL
	30 mM	0.2371 mL	1.1856 mL	2.3713 mL	5.9282 mL
	40 mM	0.1778 mL	0.8892 mL	1.7785 mL	4.4462 mL
	50 mM	0.1423 mL	0.7114 mL	1.4228 mL	3.5569 mL
	60 mM	0.1186 mL	0.5928 mL	1.1856 mL	2.9641 mL
	80 mM	0.0889 mL	0.4446 mL	0.8892 mL	2.2231 mL
	100 mM	0.0711 mL	0.3557 mL	0.7114 mL	1.7785 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.