2-Isobutyl-3-methoxypyrazine

Art. -Nr.: HY-W017141 Reinheit: 99.83%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

2-Isobutyl-3-methoxypyrazine is an aroma constituent in grapes andwines, green pepper and asparagus.

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2-Isobutyl-3-methoxypyrazine Chemische Struktur

CAS. Nr. : 24683-00-9

Größe	Verfügbarkeit	Menge
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Auf Lager	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Auf Lager	Estimated Time of Arrival: December 31
Liquid
500 mg	Auf Lager	Estimated Time of Arrival: December 31
1 g	Auf Lager	Estimated Time of Arrival: December 31
5 g	Angebot einholen
10 g	Angebot einholen

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This product is a controlled substance and not for sale in your territory.

Other Forms of 2-Isobutyl-3-methoxypyrazine:

2-Isobutyl-3-methoxypyrazine-d₃ In-stock
2-Isobutyl-3-methoxypyrazine-d₉ Angebot einholen
2-Isobutyl-3-methoxypyrazine (Standard) Angebot einholen

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biologische Aktivität
Reinheit & Dokumentation
Verweise
Kundenbewertung

Beschreibung

2-Isobutyl-3-methoxypyrazine is an aroma constituent in grapes andwines, green pepper and asparagus^[1].

Molekulargewicht

166.22

Formel

C₉H₁₄N₂O

CAS. Nr.

24683-00-9

Appearance

Liquid (Density: 1.000±0.06 g/cm³)

Color

Colorless to light yellow

SMILES

COC1=NC=CN=C1CC(C)C

Initial Source

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Store at room temperature 3 years

In solvent	-80°C	2 years
	-20°C	1 year

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 50 mg/mL (300.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.0161 mL	30.0806 mL	60.1612 mL
5 mM	1.2032 mL	6.0161 mL	12.0322 mL
10 mM	0.6016 mL	3.0081 mL	6.0161 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (15.04 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (15.04 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (15.04 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Reinheit & Dokumentation

Purity: 99.83%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (249 KB) HNMR (129 KB) GC (258 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Katja Suklje, et al. Classification of grape berries according to diameter and total soluble solids to study the effect of light and temperature on methoxypyrazine, glutathione, and hydroxycinnamate evolution during ripening of Sauvignon blanc (Vitis vinifera L.). J Agric Food Chem. 2012 Sep 19;60(37):9454-61. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.0161 mL	30.0806 mL	60.1612 mL	150.4031 mL
	5 mM	1.2032 mL	6.0161 mL	12.0322 mL	30.0806 mL
	10 mM	0.6016 mL	3.0081 mL	6.0161 mL	15.0403 mL
	15 mM	0.4011 mL	2.0054 mL	4.0107 mL	10.0269 mL
	20 mM	0.3008 mL	1.5040 mL	3.0081 mL	7.5202 mL
	25 mM	0.2406 mL	1.2032 mL	2.4064 mL	6.0161 mL
	30 mM	0.2005 mL	1.0027 mL	2.0054 mL	5.0134 mL
	40 mM	0.1504 mL	0.7520 mL	1.5040 mL	3.7601 mL
	50 mM	0.1203 mL	0.6016 mL	1.2032 mL	3.0081 mL
	60 mM	0.1003 mL	0.5013 mL	1.0027 mL	2.5067 mL
	80 mM	0.0752 mL	0.3760 mL	0.7520 mL	1.8800 mL
	100 mM	0.0602 mL	0.3008 mL	0.6016 mL	1.5040 mL