2. Stem Cell/Wnt
  3. Wnt
  4. WNT7A-IN-1 sodium

WNT7A-IN-1 sodium (1365-0109), a WNT7A inhibitor, disrupts the protein-protein interaction between WNT7A and its receptor FZD5, resulting in the upregulation of MHC-I expression. WNT7A-IN-1 sodium significantly increases the expression of MHC-I and p-p65,while concurrently reducing the expression of active β-catenin. WNT7A-IN-1 sodium (compound F) is also a photographic sensitizer in the green spectral region.

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WNT7A-IN-1 sodium

WNT7A-IN-1 sodium 화학구조

CAS No. : 33628-03-4

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg   견적 받기  
50 mg   견적 받기  

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of WNT7A-IN-1 sodium:

WNT7A-IN-1 sodium Related Antibodies

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Wnt1 Wnt3 Wnt5 Wnt7 Wnt11

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

WNT7A-IN-1 sodium (1365-0109), a WNT7A inhibitor, disrupts the protein-protein interaction between WNT7A and its receptor FZD5, resulting in the upregulation of MHC-I expression. WNT7A-IN-1 sodium significantly increases the expression of MHC-I and p-p65,while concurrently reducing the expression of active β-catenin[1]. WNT7A-IN-1 sodium (compound F) is also a photographic sensitizer in the green spectral region[2].

IC50 & Target

Wnt7A

 

분자량

722.80

화학식

C37H35N2NaO8S2
CAS No.
Appearance

Solid

Color

Orange to red

SMILES

O=S([O-])(CCC[N+]1=C(/C=C(CC)/C=C2OC3=C(N\2CCCS(=O)(O[Na])=O)C=C(C4=CC=CC=C4)C=C3)OC5=CC=C(C6=CC=CC=C6)C=C51)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도
In Vitro: 

DMSO : 100 mg/mL (138.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3835 mL 6.9175 mL 13.8351 mL
5 mM 0.2767 mL 1.3835 mL 2.7670 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 98.05%

SDS (393 KB)

COA (253 KB) HNMR (392 KB) LCMS (89 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3835 mL 6.9175 mL 13.8351 mL 34.5877 mL
5 mM 0.2767 mL 1.3835 mL 2.7670 mL 6.9175 mL
10 mM 0.1384 mL 0.6918 mL 1.3835 mL 3.4588 mL
15 mM 0.0922 mL 0.4612 mL 0.9223 mL 2.3058 mL
20 mM 0.0692 mL 0.3459 mL 0.6918 mL 1.7294 mL
25 mM 0.0553 mL 0.2767 mL 0.5534 mL 1.3835 mL
30 mM 0.0461 mL 0.2306 mL 0.4612 mL 1.1529 mL
40 mM 0.0346 mL 0.1729 mL 0.3459 mL 0.8647 mL
50 mM 0.0277 mL 0.1384 mL 0.2767 mL 0.6918 mL
60 mM 0.0231 mL 0.1153 mL 0.2306 mL 0.5765 mL
80 mM 0.0173 mL 0.0865 mL 0.1729 mL 0.4323 mL
100 mM 0.0138 mL 0.0692 mL 0.1384 mL 0.3459 mL
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WNT7A-IN-1 sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

WNT7A-IN-133628-03-4WntWNT7A inhibitorphotographic sensitizergreen spectral regionMHC-Ip-p65Inhibitorinhibitorinhibit

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상품명:
WNT7A-IN-1 sodium
Cat. No.:
HY-D1474
수량:
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SAFETY DATA SHEET (SDS)

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