4-Formylaminoantipyrine

Art. -Nr.: HY-133588 Reinheit: 99.97%: Data Sheet
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SDS
Handling Instructions
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4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo.

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4-Formylaminoantipyrine Chemische Struktur

CAS. Nr. : 1672-58-8

Größe	Verfügbarkeit	Menge
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Auf Lager	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Auf Lager	Estimated Time of Arrival: December 31
Solid
25 mg	Auf Lager	Estimated Time of Arrival: December 31
50 mg	Auf Lager	Estimated Time of Arrival: December 31
100 mg	Auf Lager	Estimated Time of Arrival: December 31
200 mg	Angebot einholen
500 mg	Angebot einholen

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Other Forms of 4-Formylaminoantipyrine:

4-Formylaminoantipyrine-d₃ Angebot einholen
4-Formylaminoantipyrine (Standard) Angebot einholen

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

Human Endogenous Metabolite Microbial Metabolite

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Beschreibung

4-Formylaminoantipyrine is an excreted metabolite of aminophenazone. Aminophenazone is a pyrazolone with analgesic, anti-inflammatory, and antipyretic effects in vivo^[1].

Molekulargewicht

231.25

Formel

C₁₂H₁₃N₃O₂

CAS. Nr.

1672-58-8

Appearance

Solid

Color

Off-white to light yellow

SMILES

O=CNC1=C(C)N(C)N(C2=CC=CC=C2)C1=O

Structure Classification

Others

Initial Source

Endogenous metabolite

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 100 mg/mL (432.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.3243 mL	21.6216 mL	43.2432 mL
5 mM	0.8649 mL	4.3243 mL	8.6486 mL
10 mM	0.4324 mL	2.1622 mL	4.3243 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 99.97%

Select Batch:

Data Sheet (273 KB) SDS (392 KB)

COA (251 KB) HNMR (243 KB) RP-HPLC (245 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

Verweise

[1]. M Levy, et al. Impairment of the metabolism of dipyrone in asymptomatic carriers of the hepatitis B virus. Clin Pharmacol Ther [Content Brief]

[2]. A Noda, et al.Formation of 4-formylaminoantipyrine as a new metabolite of aminopyrine. II. Enzymatic demethylation and oxidation of aminopyrine and 4-monomethylaminoantipyrine. Chem Pharm Bull (Tokyo).1976 Dec;24(12):3229-31. [Content Brief]

[3]. David do C Malvar, et al. Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. Br J Pharmacol. 2014 Aug;171(15):3666-79. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.3243 mL	21.6216 mL	43.2432 mL	108.1081 mL
	5 mM	0.8649 mL	4.3243 mL	8.6486 mL	21.6216 mL
	10 mM	0.4324 mL	2.1622 mL	4.3243 mL	10.8108 mL
	15 mM	0.2883 mL	1.4414 mL	2.8829 mL	7.2072 mL
	20 mM	0.2162 mL	1.0811 mL	2.1622 mL	5.4054 mL
	25 mM	0.1730 mL	0.8649 mL	1.7297 mL	4.3243 mL
	30 mM	0.1441 mL	0.7207 mL	1.4414 mL	3.6036 mL
	40 mM	0.1081 mL	0.5405 mL	1.0811 mL	2.7027 mL
	50 mM	0.0865 mL	0.4324 mL	0.8649 mL	2.1622 mL
	60 mM	0.0721 mL	0.3604 mL	0.7207 mL	1.8018 mL
	80 mM	0.0541 mL	0.2703 mL	0.5405 mL	1.3514 mL
	100 mM	0.0432 mL	0.2162 mL	0.4324 mL	1.0811 mL