2. Metabolic Enzyme/Protease
  3. Lipoxygenase
  4. 5-LOX-IN-1

5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation.

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5-LOX-IN-1

5-LOX-IN-1 Estructura química

No. CAS : 55040-82-9

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 En stock
Solution
10 mM * 1 mL in DMSO En stock
Solid
5 mg En stock
10 mg En stock
25 mg En stock
50 mg En stock
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500 mg   Obtener un presupuesto  

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5-LOX-IN-1 Related Antibodies

Top Publications Citing Use of Products

Ver todos los productos específicos de isoformas Lipoxygenase:

Ver todas las isoformas
5-LOX 12-LOX 15-LOX

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Descripciòn

5-LOX-IN-1 (compound 2b) is an inhibitor of human 5-Lipoxygenase (5-LOX) with an IC50 value of 2.3 μM. 5-LOX-IN-1 can be used for the research of inflammation[1].

IC50 & Target

IC50: 2.3 μM (5-LOX)[1]
In Vitro

5-LOX-IN-1 (0-10 μM) inhibits 5-LOX with an IC50 value of 2.3 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

5-LOX-IN-1 Related Antibodies
Peso molecular

350.43

Fòrmula

C20H18N2O2S
No. CAS
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=C(C2=CC=CC=C2)N=C(N3CCOCC3)S1)C4=CC=CC=C4
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (285.36 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8536 mL 14.2682 mL 28.5364 mL
5 mM 0.5707 mL 2.8536 mL 5.7073 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8536 mL 14.2682 mL 28.5364 mL 71.3409 mL
5 mM 0.5707 mL 2.8536 mL 5.7073 mL 14.2682 mL
10 mM 0.2854 mL 1.4268 mL 2.8536 mL 7.1341 mL
15 mM 0.1902 mL 0.9512 mL 1.9024 mL 4.7561 mL
20 mM 0.1427 mL 0.7134 mL 1.4268 mL 3.5670 mL
25 mM 0.1141 mL 0.5707 mL 1.1415 mL 2.8536 mL
30 mM 0.0951 mL 0.4756 mL 0.9512 mL 2.3780 mL
40 mM 0.0713 mL 0.3567 mL 0.7134 mL 1.7835 mL
50 mM 0.0571 mL 0.2854 mL 0.5707 mL 1.4268 mL
60 mM 0.0476 mL 0.2378 mL 0.4756 mL 1.1890 mL
80 mM 0.0357 mL 0.1784 mL 0.3567 mL 0.8918 mL
100 mM 0.0285 mL 0.1427 mL 0.2854 mL 0.7134 mL
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5-LOX-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

5-LOX-IN-155040-82-9LipoxygenaseLOX2-amino thiazoleanalogueanti-inflammatoryinflammationDPPHredoxInhibitorinhibitorinhibit

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Inquiry Information

Nombre del producto:
5-LOX-IN-1
Cat. No.:
HY-148134
Cantidad:
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