2. Metabolic Enzyme/Protease Anti-infection
  3. Drug Metabolite Bacterial
  4. 6-Aminopenicillanic acid

6-Aminopenicillanic acid  (Synonyms: 6-APA)

製品番号: HY-W013549 純度: 98.0%
COA 取扱説明書 Technical Support

6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses.

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6-Aminopenicillanic acid

6-Aminopenicillanic acid 構造式

CAS 番号 : 551-16-6

容量 価格（税別） 在庫状況 数量
500 mg $25 在庫あり
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6-Aminopenicillanic acid 関連抗体

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製品説明

6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses[1][2][3][4].

体外実験

6-Aminopenicillanic acid (Sodium 6-aminopenicillanate, 0.34-3.4 μmol/mL, 4-5 h) can induce spheroplast formation in Gram-negative bacteria[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-Aminopenicillanic acid 関連抗体
体内実験

6-Aminopenicillanic acid (injected with penicillin emulsified in complete Freund's adjuvant; intradermal and s.c. injection; multiple times) induces a more potent antibody response in rabbits compared to Penicillins G (HY-N7139), 0, or V (HY-B0975A)[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

216.26

分子式

C8H12N2O3S
CAS 番号
Appearance

Solid

Color

Off-white to light yellow

SMILES

[C@H]12SC([C@@H](N1C(=O)[C@H]2N)C(=O)O)(C)C
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
溶剤 & 溶解度
体外: 

0.1 M HCl : 12.5 mg/mL (57.80 mM; ultrasonic and adjust pH to 2 with HCl)

0.1 M NaOH : 5 mg/mL (23.12 mM; Need ultrasonic)

H2O : 0.33 mg/mL (1.53 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6241 mL 23.1203 mL 46.2406 mL
5 mM 0.9248 mL 4.6241 mL 9.2481 mL
10 mM 0.4624 mL 2.3120 mL 4.6241 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

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体積 （終了）

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
純度とドキュメンテーション

純度: 98.0%

COA (256 KB) HNMR (256 KB)

取扱説明書 (2659 KB)
参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / 0.1 M NaOH / 0.1 M HCl 1 mM 4.6241 mL 23.1203 mL 46.2406 mL 115.6016 mL
0.1 M NaOH / 0.1 M HCl 5 mM 0.9248 mL 4.6241 mL 9.2481 mL 23.1203 mL
10 mM 0.4624 mL 2.3120 mL 4.6241 mL 11.5602 mL
15 mM 0.3083 mL 1.5414 mL 3.0827 mL 7.7068 mL
20 mM 0.2312 mL 1.1560 mL 2.3120 mL 5.7801 mL
0.1 M HCl 25 mM 0.1850 mL 0.9248 mL 1.8496 mL 4.6241 mL
30 mM 0.1541 mL 0.7707 mL 1.5414 mL 3.8534 mL
40 mM 0.1156 mL 0.5780 mL 1.1560 mL 2.8900 mL
50 mM 0.0925 mL 0.4624 mL 0.9248 mL 2.3120 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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6-Aminopenicillanic acid Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Aminopenicillanic acid551-16-66-APADrug MetaboliteBacterialβ-lactamantibioticsPenicillinGPenGacylasePAInhibitorinhibitorinhibit

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HY-W013549
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