2. Metabolic Enzyme/Protease Anti-infection
  3. Drug Metabolite Bacterial
  4. 6-Aminopenicillanic acid

6-Aminopenicillanic acid  (Synonyms: 6-APA)

Cat. No.: HY-W013549 Pureza: 98.0%
COA
SDS
Instrucciones de manejo Technical Support

6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses.

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6-Aminopenicillanic acid

6-Aminopenicillanic acid Estructura química

No. CAS : 551-16-6

Tamaño Precio Stock Cantidad
500 mg En stock
1 g   Obtener un presupuesto  
5 g   Obtener un presupuesto  

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Other Forms of 6-Aminopenicillanic acid:

6-Aminopenicillanic acid Related Antibodies

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Descripciòn

6-Aminopenicillanic acid (6-APA) is a parent amine, an important precursor for the synthesis of β-lactam antibiotics and an antibacterial agent. 6-Aminopenicillanic acid interferes with cell wall synthesis during bacterial division in a manner similar to penicillin. 6-Aminopenicillanic acid has antibacterial activity against Gram-negative bacteria. 6-Aminopenicillanic acid is mainly used in the study of Penicillin-associated immune responses[1][2][3][4].

In Vitro

6-Aminopenicillanic acid (Sodium 6-aminopenicillanate, 0.34-3.4 μmol/mL, 4-5 h) can induce spheroplast formation in Gram-negative bacteria[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

6-Aminopenicillanic acid Related Antibodies
In Vivo

6-Aminopenicillanic acid (injected with penicillin emulsified in complete Freund's adjuvant; intradermal and s.c. injection; multiple times) induces a more potent antibody response in rabbits compared to Penicillins G (HY-N7139), 0, or V (HY-B0975A)[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Peso molecular

216.26

Fòrmula

C8H12N2O3S
No. CAS
Appearance

Solid

Color

Off-white to light yellow

SMILES

[C@H]12SC([C@@H](N1C(=O)[C@H]2N)C(=O)O)(C)C
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvente y solubilidad
In Vitro: 

0.1 M HCl : 12.5 mg/mL (57.80 mM; ultrasonic and adjust pH to 2 with HCl)

0.1 M NaOH : 5 mg/mL (23.12 mM; Need ultrasonic)

H2O : 0.33 mg/mL (1.53 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6241 mL 23.1203 mL 46.2406 mL
5 mM 0.9248 mL 4.6241 mL 9.2481 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Calculadora de molaridad

  • Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Pureza y Documentación

Purity: 98.0%

SDS (393 KB)

COA (256 KB) HNMR (256 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / 0.1 M NaOH / 0.1 M HCl 1 mM 4.6241 mL 23.1203 mL 46.2406 mL 115.6016 mL
0.1 M NaOH / 0.1 M HCl 5 mM 0.9248 mL 4.6241 mL 9.2481 mL 23.1203 mL
10 mM 0.4624 mL 2.3120 mL 4.6241 mL 11.5602 mL
15 mM 0.3083 mL 1.5414 mL 3.0827 mL 7.7068 mL
20 mM 0.2312 mL 1.1560 mL 2.3120 mL 5.7801 mL
0.1 M HCl 25 mM 0.1850 mL 0.9248 mL 1.8496 mL 4.6241 mL
30 mM 0.1541 mL 0.7707 mL 1.5414 mL 3.8534 mL
40 mM 0.1156 mL 0.5780 mL 1.1560 mL 2.8900 mL
50 mM 0.0925 mL 0.4624 mL 0.9248 mL 2.3120 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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6-Aminopenicillanic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6-Aminopenicillanic acid551-16-66-APADrug MetaboliteBacterialβ-lactamantibioticsPenicillinGPenGacylasePAInhibitorinhibitorinhibit

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Nombre del producto:
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