2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 7-Methylguanosine 5'-diphosphate sodium

7-Methylguanosine 5'-diphosphate sodium  (Synonyms: 7-Methyl-GDP sodium; m7GDP sodium)

Cat. No.: HY-141472 Purity: 97.1%
COA
SDS
Handling Instructions Technical Support

7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues.

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7-Methylguanosine 5'-diphosphate sodium

7-Methylguanosine 5'-diphosphate sodium 화학구조

CAS No. : 104809-16-7

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg   견적 받기  
50 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

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7-Methylguanosine 5'-diphosphate sodium Related Antibodies

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  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues[1].

IC50 & Target[1]

Human Endogenous Metabolite

 

In Vitro

7-Methylguanosine 5'-diphosphate sodium inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA[1].
T. brucei mRNA decapping enzyme (TbDcp2) that cleaves 7-Methylguanosine 5'-diphosphate sodium from capped RNA to generate pRNA, a substrate for TbCe1[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

7-Methylguanosine 5'-diphosphate sodium Related Antibodies
분자량

479.21

화학식

C11H16N5NaO11P2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](O)[C@H](N2C(NC(N)=NC3=O)=C3[N+](C)=C2)O[C@@H]1COP([O-])(OP(O)(O[Na])=O)=O
Structure Classification
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도
In Vitro: 

H2O : 50 mg/mL (104.34 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0868 mL 10.4338 mL 20.8677 mL
5 mM 0.4174 mL 2.0868 mL 4.1735 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 97.1%

SDS (252 KB)

COA (250 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.0868 mL 10.4338 mL 20.8677 mL 52.1692 mL
5 mM 0.4174 mL 2.0868 mL 4.1735 mL 10.4338 mL
10 mM 0.2087 mL 1.0434 mL 2.0868 mL 5.2169 mL
15 mM 0.1391 mL 0.6956 mL 1.3912 mL 3.4779 mL
20 mM 0.1043 mL 0.5217 mL 1.0434 mL 2.6085 mL
25 mM 0.0835 mL 0.4174 mL 0.8347 mL 2.0868 mL
30 mM 0.0696 mL 0.3478 mL 0.6956 mL 1.7390 mL
40 mM 0.0522 mL 0.2608 mL 0.5217 mL 1.3042 mL
50 mM 0.0417 mL 0.2087 mL 0.4174 mL 1.0434 mL
60 mM 0.0348 mL 0.1739 mL 0.3478 mL 0.8695 mL
80 mM 0.0261 mL 0.1304 mL 0.2608 mL 0.6521 mL
100 mM 0.0209 mL 0.1043 mL 0.2087 mL 0.5217 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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7-Methylguanosine 5'-diphosphate sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

7-Methylguanosine 5'-diphosphate104809-16-77-Methyl-GDPm7GDPEndogenous MetabolitecapmRNAanalogueDcp2Inhibitorinhibitorinhibit

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상품명:
7-Methylguanosine 5'-diphosphate sodium
Cat. No.:
HY-141472
수량:
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