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  4. Acetamide

Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies.

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Acetamide

Acetamide Chemische Struktur

CAS. Nr. : 60-35-5

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
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Other Forms of Acetamide:

Acetamide Related Antibodies

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Beschreibung

Acetamide is used as an intermediate in the synthesis of methylamine, thioacetamide, and insecticides, and as a plasticizer in leather, cloth and coatings. Acetamide has carcinogenicity. Acetamide derivatives may has antioxidant activity and potential anti-inflammatory activity. Acetamide holds promise for research in the fields of anti-inflammatory and cancer studies[1][2][3].

In Vivo

Acetamide (250, 1000, 2000 mg/kg for acute exposure; p.o., once daily for 2 days; 1000 mg/kg for subchronic assay, p.o., once daily for 28 days) does not induce micronuclei in rats and mice and does not increase mutations in the rat Pig-a gene mutation assay[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar (RccHan：WIST) rats and ICR (CD1) mice
Dosage: 250, 1000, 2000 mg/kg (acute exposure); 1000 mg/kg (subchronic assay)
Administration: Oral gavage (p.o.), once daily for 2 consecutive days (acute exposure); Oral gavage (p.o.), once daily for 28 days (subchronic assay)
Result: Did not induce micronucleated polychromatic erythrocytes (MN-PCE) in either mice or rats at acute (2 day) doses of 250, 1000, or 2000 mg/kg, or in rats following treatment with 1000 mg/kg/day for 28 days.
Molekulargewicht

59.07

Formel

C2H5NO
CAS. Nr.
Appearance

Solid

Color

White to off-white

SMILES

CC(N)=O
Structure Classification
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Store at room temperature 3 years

In solvent -80°C 2 years
-20°C 1 year
Lösungsmittel & Löslichkeit
In Vitro: 

H2O : 50 mg/mL (846.45 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 16.9291 mL 84.6453 mL 169.2907 mL
5 mM 3.3858 mL 16.9291 mL 33.8581 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Reinheit & Dokumentation

Purity: 99.95%

SDS (478 KB)

COA (246 KB) HNMR (120 KB) LCMS (231 KB) GC (254 KB)

Handling Instructions (2659 KB)
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 16.9291 mL 84.6453 mL 169.2907 mL 423.2267 mL
5 mM 3.3858 mL 16.9291 mL 33.8581 mL 84.6453 mL
10 mM 1.6929 mL 8.4645 mL 16.9291 mL 42.3227 mL
15 mM 1.1286 mL 5.6430 mL 11.2860 mL 28.2151 mL
20 mM 0.8465 mL 4.2323 mL 8.4645 mL 21.1613 mL
25 mM 0.6772 mL 3.3858 mL 6.7716 mL 16.9291 mL
30 mM 0.5643 mL 2.8215 mL 5.6430 mL 14.1076 mL
40 mM 0.4232 mL 2.1161 mL 4.2323 mL 10.5807 mL
50 mM 0.3386 mL 1.6929 mL 3.3858 mL 8.4645 mL
60 mM 0.2822 mL 1.4108 mL 2.8215 mL 7.0538 mL
80 mM 0.2116 mL 1.0581 mL 2.1161 mL 5.2903 mL
100 mM 0.1693 mL 0.8465 mL 1.6929 mL 4.2323 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Acetamide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Acetamide60-35-5Environmental PollutantsEnvironmental ContaminantsWistar (RccHan：WIST) rats and ICR (CD1) miceCarcinogenicityInflammationCancerInhibitorinhibitorinhibit

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