2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Bethanechol

Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Bethanechol chloride) usually boasts enhanced water solubility and stability.

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Bethanechol

Bethanechol Chemische Struktur

CAS. Nr. : 674-38-4

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Other Forms of Bethanechol:

Bethanechol Related Antibodies

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Alle mAChR Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen
mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

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Beschreibung

Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system[1].

IC50 & Target

mAChR1

 

mAChR3

 

mAChR4

 

mAChR5

 

In Vitro

Bethanechol (0.3-300 μM) significantly reduces ileal pacemaker potentials[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bethanechol Related Antibodies
In Vivo

Bethanechol (2-12 mg/kg; i.p.) induces drinking and increased urine output of rats in a dose-dependent fashion[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female rats of the Blue Spruce Farms (Sprague-Dawley) (280-330 g) [4]
Dosage: 2 mg/kg, 4 mg/kg, 8 mg/kg, 12 mg/kg
Administration: Intraperitoneal injection
Result: Increased water intake during the first hr in a dose-dependent fashion up to the highest dose administered (12 mg/kg).
Klinische Studie
Molekulargewicht

161.22

Formel

C7H17N2O2
CAS. Nr.
SMILES

CC(OC(N)=O)C[N+](C)(C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
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Bethanechol Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bethanechol674-38-4Carbamyl-β-methylcholinemAChRMuscarinic acetylcholine receptorparasympathomimeticparasympatheticreceptorspostoperativeurinaryretentionpostpartumurinary ,retentionoverflowincontinenceInhibitorinhibitorinhibit

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