1. GPCR/G Protein
    Neuronal Signaling
  2. mAChR
  3. Bethanechol chloride

Bethanechol chloride (Synonyms: Carbamyl-β-methylcholine chloride)

Cat. No.: HY-B0406A
Handling Instructions

Bethanechol Chloride (Carbamyl-β-methylcholine chloride) is a selective muscarinic receptor agonist without any effect on nicotinic receptors.

For research use only. We do not sell to patients.

Bethanechol chloride Chemical Structure

Bethanechol chloride Chemical Structure

CAS No. : 590-63-6

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10 mM * 1 mL in Water USD 66 In-stock
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200 mg USD 60 In-stock
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5 g USD 102 In-stock
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Description

Bethanechol Chloride (Carbamyl-β-methylcholine chloride) is a selective muscarinic receptor agonist without any effect on nicotinic receptors. Target: mAChR Bethanechol Chloride (Carbamyl-β-methylcholine chloride) is a parasympathomimetic choline carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. Unlike acetylcholine, Bethanechol Chloride (Carbamyl-β-methylcholine chloride) is not hydrolyzed by cholinesterase and will therefore have a long duration of action. Oral bethanechol significantly improves contraction pressures and bolus transit in the smooth muscle portion of the esophagus in patients with severe IEM [1]. Bethanechol Chloride (Carbamyl-β-methylcholine chloride) has potential benefit in the treatment of cerebral palsy [2].

Clinical Trial
Molecular Weight

196.68

Formula

C₇H₁₇ClN₂O₂

CAS No.

590-63-6

SMILES

CC(OC(N)=O)C[N+](C)(C)C.[Cl-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (254.22 mM)

DMSO : 11.11 mg/mL (56.49 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

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Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0844 mL 25.4220 mL 50.8440 mL
5 mM 1.0169 mL 5.0844 mL 10.1688 mL
10 mM 0.5084 mL 2.5422 mL 5.0844 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

BethanecholCarbamyl-β-methylcholinemAChRMuscarinic acetylcholine receptorInhibitorinhibitorinhibit

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Bethanechol chloride
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HY-B0406A
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