2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Bethanechol

Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Bethanechol chloride) usually boasts enhanced water solubility and stability.

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Bethanechol

Bethanechol 화학구조

CAS No. : 674-38-4

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Other In-stock Forms of Bethanechol:

Other Forms of Bethanechol:

Bethanechol Related Antibodies

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mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

  • Biological Activity

  • 순도&문서

  • References

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제품 설명

Bethanechol (Carbamyl-β-methylcholine), a parasympathomimetic agent, is a mAChR agonist that exerts its effects via directly stimulating the mAChR (M1, M2, M3, M4, and M5) of the parasympathetic nervous system[1].

IC50 & Target

mAChR1

 

mAChR3

 

mAChR4

 

mAChR5

 

In Vitro

Bethanechol (0.3-300 μM) significantly reduces ileal pacemaker potentials[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bethanechol Related Antibodies
In Vivo

Bethanechol (2-12 mg/kg; i.p.) induces drinking and increased urine output of rats in a dose-dependent fashion[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female rats of the Blue Spruce Farms (Sprague-Dawley) (280-330 g) [4]
Dosage: 2 mg/kg, 4 mg/kg, 8 mg/kg, 12 mg/kg
Administration: Intraperitoneal injection
Result: Increased water intake during the first hr in a dose-dependent fashion up to the highest dose administered (12 mg/kg).
Clinical Trial
분자량

161.22

화학식

C7H17N2O2
CAS No.
SMILES

CC(OC(N)=O)C[N+](C)(C)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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Bethanechol Related Classifications

  • 몰농도 계산기

  • 농도 희석 계산기

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bethanechol674-38-4Carbamyl-β-methylcholinemAChRMuscarinic acetylcholine receptorparasympathomimeticparasympatheticreceptorspostoperativeurinaryretentionpostpartumurinary ,retentionoverflowincontinenceInhibitorinhibitorinhibit

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상품명:
Bethanechol
Cat. No.:
HY-B0406
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