LysoPC(14:0/0:0) (Synonyms: 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine)

Art. -Nr.: HY-113123 Reinheit: 99.84%: Data Sheet
COA

SDS
Handling Instructions
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LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect.

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LysoPC(14:0/0:0) Chemische Struktur

CAS. Nr. : 20559-16-4

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Other Forms of LysoPC(14:0/0:0):

LysoPC(14:0/0:0)-d₇ In-stock
14:0 Lyso PC-d₂₇ In-stock

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

Human Endogenous Metabolite Microbial Metabolite

Biologische Aktivität
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Beschreibung

IC₅₀ & Target

Human Endogenous Metabolite

In Vivo

Of the saturated fatty acid-containing L-α-lysolecithins (LPC), palmitoyl-LPC shows the strongest antispasmodic effect against acetylcholine- or histamine-induced guinea pig ileum contraction; the order of potency of the others is (LysoPC(14:0/0:0)) myristoyl- > stearoyl-, lauroyl- > decanoyl-LPC. Incorporation of a cis-double bond into the C18 fatty acid chain of LPC resulted in a slight decrease of the antispasmodic effect^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

467.58

Formel

C₂₂H₄₆NO₇P

CAS. Nr.

20559-16-4

Appearance

Solid

Color

White to light yellow

SMILES

CCCCCCCCCCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O

Structure Classification

Others

Initial Source

Endogenous metabolite

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

Ethanol : 50 mg/mL (106.93 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1387 mL	10.6934 mL	21.3867 mL
5 mM	0.4277 mL	2.1387 mL	4.2773 mL
10 mM	0.2139 mL	1.0693 mL	2.1387 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 99.84%

Select Batch:

Data Sheet (266 KB) SDS (558 KB)

COA (240 KB) HNMR (269 KB) RP-HPLC (242 KB) MS (84 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Tsukatani H, et al.Comparison of antispasmodic effect of synthetic lysolecithins with various fatty acid moieties on guinea pig ileum.J Pharmacobiodyn. 1984 Jun;7(6):400-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol	1 mM	2.1387 mL	10.6934 mL	21.3867 mL	53.4668 mL
	5 mM	0.4277 mL	2.1387 mL	4.2773 mL	10.6934 mL
	10 mM	0.2139 mL	1.0693 mL	2.1387 mL	5.3467 mL
	15 mM	0.1426 mL	0.7129 mL	1.4258 mL	3.5645 mL
	20 mM	0.1069 mL	0.5347 mL	1.0693 mL	2.6733 mL
	25 mM	0.0855 mL	0.4277 mL	0.8555 mL	2.1387 mL
	30 mM	0.0713 mL	0.3564 mL	0.7129 mL	1.7822 mL
	40 mM	0.0535 mL	0.2673 mL	0.5347 mL	1.3367 mL
	50 mM	0.0428 mL	0.2139 mL	0.4277 mL	1.0693 mL
	60 mM	0.0356 mL	0.1782 mL	0.3564 mL	0.8911 mL
	80 mM	0.0267 mL	0.1337 mL	0.2673 mL	0.6683 mL
	100 mM	0.0214 mL	0.1069 mL	0.2139 mL	0.5347 mL

LysoPC(14:0/0:0) Related Classifications

Neurological Disease Metabolic Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LysoPC(14:0/0:0)20559-16-414:0 Lyso PC 1-myristoyl-sn-glycero-3-phosphatidylcholineEndogenous MetaboliteAntispasmodicL-α-lysolecithinslysophospholipidphosphorylcholineInhibitorinhibitorinhibit

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