1. Natural Products
  2. Plants
  3. Simaroubaceae


Simaroubaceae (46):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19543
    Brusatol 14907-98-3 99.89%
    Brusatol (NSC 172924) is a unique inhibitor of the Nrf2 pathway that sensitizes a broad spectrum of cancer cells to Cisplatin and other chemotherapeutic agents. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism. Brusatol can be developed into an adjuvant chemotherapeutic agent. Brusatol increases cellular apoptosis.
  • HY-N0840
    Bruceantin 41451-75-6 99.94%
    Bruceantin(NSC165563) is first isolated from Brucea javanica, a tree used in Ethiopia for the treatment of cancer, and activity was observed against B16 melanoma, colon 38, and L1210 and P388 leukemia in mice.
  • HY-N1943
    Ailanthone 981-15-7 99.76%
    Ailanthone (Δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) (IC50=69 nM) and constitutively active truncated AR splice variants (AR1-651 IC50=309 nM).
  • HY-N0841
    Bruceine A 25514-31-2 98.01%
    Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.
    Bruceine A
  • HY-N1203
    (5α)-Stigmastane-3,6-dione 22149-69-5
    (5α)-Stigmastane-3,6-dione is a naturally occurring sterol that could be isolated from fruits of Ailanthus altissima Swingle. Antimicrobial Activity..
  • HY-N11016
    1-Methoxymethyl-β-carboline 55854-60-9
    1-Methoxymethyl-β-carboline is a natural product isolated from the root of Eurycoma longifolia.
  • HY-N10899
    Bruceine J 948038-38-8
    Bruceine J, a quassinoid, is a nature product that could be isolated from fruits of Br. jaVanica. Bruceine J has anti-Babesial activity.
    Bruceine J
  • HY-N3711
    Dehydrocrenatine 26585-13-7
    Dehydrocrenatidine, a β-carboline alkaloid that can be isolated from Picrasma quassioides. Dehydrocrenatidine induces cell apoptosis by activates ERK and JNK. Dehydrocrenatidine inhibits invasion and migration of cancer cells, it also suppresses neuronal excitability to exert analgesic effects.
  • HY-N4210
    Yadanziolide A 95258-14-3 99.41%
    Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects.
    Yadanziolide A
  • HY-N3014
    Bruceine D 21499-66-1 99.53%
    Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity. Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L.
    Bruceine D
  • HY-N7532
    Yadanzioside I 99132-95-3
    Yadanzioside I is a potent anti-tobacco mosaic virus (TMV) quassinoid with an IC50 of 4.22 μM.
    Yadanzioside I
  • HY-111806
    3,7,4'-Trihydroxyflavone 2034-65-3 98.75%
    3,7,4'-Trihydroxyflavone, isolated from Rhus javanica var. roxburghiana, is a flavonoid with DNA strand-scission activity.
  • HY-N1581
    Quassin 76-78-8 ≥98.0%
    Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract of Quassia amara. Quassin inhibits P. falciparum with an IC50 of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity.
  • HY-N4257
    Yadanzioside A 95258-15-4 ≥98.0%
    Yadanziolide A, a quassinoid glycoside from Brucea javanica, has antitumor activity.
    Yadanzioside A
  • HY-N10450
    Kumujian A 72755-19-2 98.32%
    Kumujian A (1-Ethoxycarbonyl-β-carboline), an anti-inflammatory agent, inhibits both superoxide anion generation (IC50 = 4.87 μg/mL) and elastase release (IC50 = 6.29 μg/mL).
    Kumujian A
  • HY-N7190
    Yadanzioside F 95258-11-0 ≥98.0%
    Yadanzioside F is one of the toxic components found in Brucea javanica. Brucea javanica has demonstrated a variety of antitumoral, antimalarial, and anti-inflammatory properties.
    Yadanzioside F
  • HY-N7189
    Yadanzioside C 95258-16-5
    Yadanzioside C is a quassinoid glucoside found in seeds of Brucea amarissima.
    Yadanzioside C
  • HY-133096
    Yadanzioside K 101559-98-2
    Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
    Yadanzioside K
  • HY-N3015
    Bruceine E 21586-90-3
    Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ)-induced diabetic rats at lower dose.
    Bruceine E
  • HY-W067479
    (E)-Cinnamamide 22031-64-7
    (E)-Cinnamamide, the less active isomer of Cinnamamide. Cinnamamide, a derivative of the plant secondary compound Cinnamic acid. Cinnamamide is effective as a non-lethal chemical repellent suitable for reducing avian pest damage.