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  4. Brucea antidysenterica J.F.Mill.

Brucea antidysenterica J.F.Mill.

Brucea antidysenterica J.F.Mill. (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N8146
    Bruceantinol 53729-52-5 98.89%
    Bruceantinol, a quassinoid isolated from Brucea javanica, inhibits pepper mottle virus in pepper. Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc.
    Bruceantinol