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Cat. No.: HY-N18237

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Bruceanol A

Bruceanol A is an antileukemic quassinoid glycoside isolated from Brucea javanica. Bruceanol A exhibits antileukemic activity against P-388 lymphocytic leukemia in vivo. Bruceanol A can be used in studies related to P-388 lymphocytic leukemia.

For research use only. We do not sell to patients.

CAS No.: 101391-06-4
Formula: C₂₈H₃₀O₁₁
Molecular Weight:542.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Bruceanol A Chemical Structure

CAS No.: 101391-06-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vivo

Bruceanol A (Compound 1) (0.5-2 mg/kg; 3 days) exhibits significant in vivo antileukemic activity against P-388 lymphocytic leukemia, with T/C values ranging from 129% to 134% when administered at doses of 0.5, 1, and 2 mg/kg according to a 3-day dosing regimen^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 101391-06-4
Molecular Weight 542.53
Formula C₂₈H₃₀O₁₁
SMILES

COC([C@]12[C@@]3([H])[C@@]4(CO2)[C@@]([C@H]([C@@H]1O)O)([H])[C@@]5([C@@](C(C)=CC([C@H]5O)=O)([H])C[C@@]4([H])OC([C@@H]3OC(C6=CC=CC=C6)=O)=O)C)=O
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Okano M, et al. Antitumor agents, 74. Bruceanol-A and -B, two new antileukemic quassinoids from Brucea antidysenterica. J Nat Prod. 1985 Nov-Dec;48(6):972-5. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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