- Natural Products
- Plants
- Simaroubaceae
- Quassia amaraL.
Quassia amaraL.
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Quassia amaraL. (2)
- Formula: C24H34O6
- Molecular Weight: 418.52
16α-O-Ethylneoquassin is a natural diterpene.
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- Formula: C14H12N2O2
- Molecular Weight: 240.26
Picrasidine I is an anti-inflammatory and anti-osteoclastogenic dimeric alkaloid that can be isolated from Picrasma quassioides. Picrasidine I inducs cell cycle arrest, and triggers cell apoptosis by downregulats ERK and Akt pathways. Picrasidine I inhibits the activation of MAPKs, NF-κB and ROS generation, and suppresses the expression of c-Fos and NFATc1.
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