2. 天然物
  3. Plants
  4. Liliaceae
  5. Ophiopogon japonicus (L. f.) Ker-Gawl.

Ophiopogon japonicus (L. f.) Ker-Gawl.

Ophiopogon japonicus (L. f.) Ker-Gawl. (40):

製品番号 製品名 CAS 番号 純度 構造式
  • HY-N0496
    Ruscogenin

    ルスコゲニン

    		472-11-7 99.85%
    Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity.
    Ruscogenin
  • HY-N0515
    Ophiopogonin D

    Ophiopogonin D

    		945619-74-9 99.80%
    Ophiopogonin D can be isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D can inhibit isteoclastic differentiation in RAW264.7 cells. Ophiopogonin D has protective effect as an antioxidant in H2O2-induced endothelial injury. Ophiopogonin D blocks ERK signaling cascades. Ophiopogonin D alleviates high-fat diet-induced metabolic syndrome and changes the structure of gut microbiota in mice. Ophiopogonin D has been used against inflammatory, metabolic and cardiovascular diseases.
    Ophiopogonin D
  • HY-N2438
    Methylophiopogonanone B 74805-91-7 99.84%
    Methylophiopogonanone B is a homoisoflavonoid compound. Methylophiopogonanone B can be isolated from O. japonicus root. Methylophiopogonanone B promotes Rho activation and Tubulin depolymerization. Methylophiopogonanone B significantly increases GTP-Rho, but not GTP-Rac or GTP-CDC42. Methylophiopogonanone B induces cell morphological change via melanocyte dendrite retraction and stress fiber formation. Methylophiopogonanone B exhibits strong antioxidant activity. Methylophiopogonanone B can be used in the research of cervical cancer.
    Methylophiopogonanone B
  • HY-N1887
    4-Allylcatechol 1126-61-0 98.60%
    4-Allylcatechol (4-Allylpyrocatechol) is a xylan which has oral activity and can be isolated from the root of Piper taiwanense. 4-Allylcatechol has a strong inhibitory activity against collagen-induced platelet aggregation (IC50 = 5.3 μM). In addition, 4-Allylcatechol has anti-tuberculosis activity against Mycobacterium tuberculosis H37Rv (MIC = 27.6 μg/mL).
    4-Allylcatechol
  • HY-N2230
    N-p-trans-Coumaroyltyramine 36417-86-4 99.28%
    N-p-trans-Coumaroyltyramine is a natural phenolic amide compound and an inhibitor of AChE (IC50: 122 μM) and α-glucosidase (IC50: 2.7 μM). N-p-trans-Coumaroyltyramine also has anti-trypanosomal activity, with an IC50 of 13.3 µM against T. brucei rhodesiense. N-p-trans-Coumaroyltyramine can be used in the research of diseases such as Alzheimer's disease.
    N-p-trans-Coumaroyltyramine
  • HY-N8013
    5-O,8-Dimethylophiopogonanone B 1234211-72-3
    5-O,8-Dimethylophiopogonanone B is a homoisoflavanone found in the tuberous roots of Ophiopogon japonicus. 5-O,8-Dimethylophiopogonanone B shows cytotoxicity against cancer cells. 5-O,8-Dimethylophiopogonanone B can be used for the research of cancer, such as breast cancer.
    5-O,8-Dimethylophiopogonanone B
  • HY-N2437
    Methylophiopogonanone A 74805-92-8 99.65%
    Methylophiopogonanone A, a major homoisoflavonoid in Ophiopogon japonicas, has both anti-oxidative and anti-inflammatory properties.
    Methylophiopogonanone A
  • HY-N2441
    Methylophiopogonone A 74805-90-6 99.84%
    Methylophiopogonone A, a homoisoflavonoid isolated from the tuberous roots of Ophiopogon japonicas, shows anti-inflammatory activity.
    Methylophiopogonone A
  • HY-N3504
    Ophiopogonin D' 65604-80-0 99.94%
    Ophiopogonin D' is a steroidal saponin and a SIRT1 activator. Ophiopogonin D' can also regulate the activities of transporters OATP1B1 and OATP1B3. Ophiopogonin D' exhibits certain toxicity to tumor cells. Ophiopogonin D' can be used in tumor research.
    Ophiopogonin D'
  • HY-N2231
    N-trans-p-coumaroyloctopamine 66648-45-1 99.21%
    N-trans-p-coumaroyloctopamine is a phenylpropanoid amide isolated from eggplant (Solanum melongena L.).
    N-trans-p-coumaroyloctopamine
  • HY-N11985
    Ophiopogonone C 477336-77-9
    Ophiopogonone C (compound 3) is an isoflavone compound isolated from the ethanol extract of Ophiopogon japonicus tubers.
    Ophiopogonone C
  • HY-N7942
    6-Aldehydoisoophiopogonone A 112500-90-0 99.04%
    6-Aldehydoisoophiopogonone A is a homoisoflavonoid that can be isolated from Ophiopogon japonicus.
    6-Aldehydoisoophiopogonone A
  • HY-N6059
    Ophiopogonanone A 75239-63-3 99.24%
    Ophiopogonanone A is a homoisoflavonoidal compound isolated as a constitutent of Ophiopogonis tuber.
    Ophiopogonanone A
  • HY-N2174
    Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside 128502-94-3 99.85%
    Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside, a terpenoid glycoside from Ophiopogon japonicus roots, has good pharmacological effects on the cardiovascular system.
    Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside
  • HY-N2175
    Cixiophiopogon A 288143-27-1 99.89%
    Cixiophiopogon A, a steroidal glycoside, obtained from the tuberous roots of Ophiopogon japonicus (Liliaceae).
    Cixiophiopogon A
  • HY-N0515R
    Ophiopogonin D (Standard) 945619-74-9
    Ophiopogonin D (Standard) is the analytical standard of Ophiopogonin D. This product is intended for research and analytical applications. Ophiopogonin D can be isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D can inhibit isteoclastic differentiation in RAW264.7 cells. Ophiopogonin D has protective effect as an antioxidant in H2O2-induced endothelial injury. Ophiopogonin D blocks ERK signaling cascades. Ophiopogonin D alleviates high-fat diet-induced metabolic syndrome and changes the structure of gut microbiota in mice. Ophiopogonin D has been used against inflammatory, metabolic and cardiovascular diseases.
    Ophiopogonin D (Standard)
  • HY-N5050
    OJV-VI 125150-67-6 99.81%
    OJV-VI is found in ophiopogonis.
    OJV-VI
  • HY-N6061
    Ophiopogonin C 65586-25-6 99.0%
    Ophiopogonin C, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin C shows cytotoxic activity against two human tumor cell lines MG-63 and SNU387 with IC50s of 19.76 μM and 15.51 μM, respectively.
    Ophiopogonin C
  • HY-N0496R
    Ruscogenin (Standard) 472-11-7
    Ruscogenin (Standard) is the analytical standard of Ruscogenin. This product is intended for research and analytical applications. Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway. Ruscogenin exerts significant anti-inflammatory and anti-thrombotic activities. Ruscogenin has orally bioactivity.
    Ruscogenin (Standard)
  • HY-N2230R
    N-p-trans-Coumaroyltyramine (Standard) 36417-86-4
    N-p-trans-Coumaroyltyramine (Standard) is the analytical standard of N-p-trans-Coumaroyltyramine (HY-N2230). This product is intended for research and analytical applications. N-p-trans-Coumaroyltyramine is a natural phenolic amide compound and an inhibitor of AChE (IC50: 122 μM) and α-glucosidase (IC50: 2.7 μM). N-p-trans-Coumaroyltyramine also has anti-trypanosomal activity, with an IC50 of 13.3 µM against T. brucei rhodesiense. N-p-trans-Coumaroyltyramine can be used in the research of diseases such as Alzheimer's disease.
    N-p-trans-Coumaroyltyramine (Standard)