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Polygalaceae

Polygalaceae (35):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1414
    3',6-Disinapoylsucrose 139891-98-8 98.15%
    3',6-Disinapoylsucrose, the index component of Yuanzhi (Polygala tenuifolia Willd), possesses potent antioxidant activity and antidepressant effect.
    3',6-Disinapoylsucrose
  • HY-W012123
    3,4,5-Trimethoxycinnamic acid 90-50-6 99.22%
    3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of Polygala tenuifolia WILLD, with anti-stress effect, prolonging the sleeping time in animals. 3,4,5-Trimethoxycinnamic acid increases expression of GAD65 and γ-subunit of GABAA receptor, but shows no effect on the amounts of α-, β-subunits.
    3,4,5-Trimethoxycinnamic acid
  • HY-N0802
    Tenuigenin 2469-34-3 99.24%
    Tenuigenin is a major active component isolated from the root of the Chinese herb Polygala tenuifolia. Tenuigenin protects against S.aureus-induced pneumonia by inhibiting NF-κB activation. Tenuigenin has anti-inflammatory effect.
    Tenuigenin
  • HY-N2492
    (E)-Methyl 4-coumarate 19367-38-5 99.83%
    (E)-Methyl 4-coumarate (Methyl 4-hydroxycinnamate), found in several plants, such as green onion (Allium cepa) or noni (Morinda citrifolia L.) leaves. (E)-Methyl 4-coumarate cooperates with Carnosic Acid in inducing apoptosis and killing acute myeloid leukemia cells, but not normal peripheral blood mononuclear cells. Antioxidant and antimicrobial activity.
    (E)-Methyl 4-coumarate
  • HY-N1479
    Polygalic acid 1260-04-4 99.25%
    Polygalic acid, a triterpenoid saponin, is considered one of the major active constituents of Polygala tenuifolia.
    Polygalic acid
  • HY-N0702
    Tenuifolin 20183-47-5 ≥98.0%
    Tenuifolin is a triterpene isolated from Polygala tenuifolia Willd, has neuroprotective effects. Tenuifolin reduces Aβ secretion by inhibiting β-secretase. Tenuifolin improves learning and memory in aged mice by decreasing AChE activity and has the potential for Alzheimer’s disease (AD) treatment.
    Tenuifolin
  • HY-N6962
    α-Spinasterol 481-18-5 99.15%
    α-Spinasterol, isolated from Spinacia oleracea, has antibacterial activity. α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively.
    α-Spinasterol
  • HY-N0801
    Polygalacic acid 22338-71-2 98.92%
    Polygalacic acid, is a triterpene, isolated from the root of Polygala tenuifolia Willd. Polygalacic acid inhibits MMP expression. Polygalacic acid may have a therapeutic effect in Osteoarthritis (OA) treatment . Polygalacic acid exerts a significant neuroprotective effect on cognitive impairment, PA improves cholinergic system reactivity by inhibiting acetylcholinesterase (AChE) activity, increasing choline acetyltransferase (ChAT) activity, and elevating levels of acetylcholine (Ach) in the hippocampus and frontal cortex.
    Polygalacic acid
  • HY-N2099
    Onjisaponin B 35906-36-6 99.10%
    Onjisaponin B is a natural product derived from Radix Polygalae. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells, and exbibits potential therapeutic effects on Parkinson disease and Huntington disease.
    Onjisaponin B
  • HY-N0392
    Polygalasaponin F 882664-74-6 99.74%
    Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .
    Polygalasaponin F
  • HY-W017100
    2-Hydroxy-6-methoxybenzoic acid 3147-64-6 98.06%
    2-Hydroxy-6-methoxybenzoic acid can be used for the determination of acetylsalicylic acid and its major metabolite, salicylic acid, in animal plasma. 2-Hydroxy-6-methoxybenzoic acid exhibits significant analgesic effects.
    2-Hydroxy-6-methoxybenzoic acid
  • HY-N2216
    Polygalasaponin XXXI 79103-90-5
    Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection.
    Polygalasaponin XXXI
  • HY-N2498
    Glomeratose A 202471-84-9 99.79%
    Glomeratose A is a lactate dehydrogenase inhibitor, isolated from Polygala tenuifolia.
    Glomeratose A
  • HY-N4268
    Tenuifoliside B 139726-36-6 98.12%
    Tenuifoliside B, a component isolated from Polygalae Radix, inhibits potassium cyanide (KCN)-induced hypoxia and scopolamine-induced memory impairment. Tenuifoliside B shows potential cognitive improvement and cerebral protective effects. Tenuifoliside B has potential to become an anti-AD lead compound.
    Tenuifoliside B
  • HY-N2159
    Lancerin 81991-99-3 99.69%
    Lancerin, isolated from the root bark of Cudraniu cochinchinensis, possesses anti-lipid peroxidation.
    Lancerin
  • HY-N1407
    Polygalaxanthone III 162857-78-5 99.76%
    Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM.
    Polygalaxanthone III
  • HY-N6803
    Polygalaxanthone XI 857859-82-6
    Polygalaxanthone XI, a xanthone glycoside isolated from the cortexes of Polygala tenuifolia, can be used in the study of expectorant, and tranquilizing agent.
    Polygalaxanthone XI
  • HY-N2263
    Skimmin 93-39-0
    Skimmin (Umbelliferone glucoside) is a coumarin found in Hydrangea paniculata, inhibits immune complex deposition, with anti-inflammatory activity.
    Skimmin
  • HY-N4293
    1,2,3,7-Tetramethoxyxanthone 22804-52-0
    1,2,3,7-Tetramethoxyxanthone is a xanthone isolated from Polygala tenuifolia.
    1,2,3,7-Tetramethoxyxanthone
  • HY-N2606
    Bernardioside A 121368-52-3
    Bernardioside A is a triterpenoid saponin isolated from Bellis bernardii.
    Bernardioside A