1. Immunology/Inflammation
    PI3K/Akt/mTOR
    NF-κB
  2. Toll-like Receptor (TLR)
    PI3K
    Akt
    NF-κB
  3. Polygalasaponin F

Polygalasaponin F 

Cat. No.: HY-N0392
Handling Instructions

Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway .

For research use only. We do not sell to patients.

Polygalasaponin F Chemical Structure

Polygalasaponin F Chemical Structure

CAS No. : 882664-74-6

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Description

Polygalasaponin F, an oleanane-type triterpenoid saponin extracted from Polygala japonica, decreases the release of the inflammatory cytokine tumor necrosis factor a (TNFa). Polygalasaponin F reduces neuroinflammatory cytokine secretion through the regulation of the TLR4-PI3K/AKT-NF-kB signaling pathway [1].

IC50 & Target

TLR4

 

PI3K

 

Akt

 

NF-κB

 

Molecular Weight

1091.24

Formula

C₅₃H₈₆O₂₃

CAS No.

882664-74-6

SMILES
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Polygalasaponin F
Cat. No.:
HY-N0392
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