2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-32806
    2-Chloro-4-methyl-3-nitropyridine 23056-39-5 ≥98.0%
    2-Chloro-4-methyl-3-nitropyridine is a pyridine derivative that can be used to synthesize 2-methoxypyridine derivatives with antibacterial and antituberculosis activities.
    2-Chloro-4-methyl-3-nitropyridine
  • HY-75800
    Lomibuvir 1026785-55-6 99.71%
    Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis.
    Lomibuvir
  • HY-76293
    I2906 331963-29-2 99.83%
    I2906 is an orally active isocitrate lyase (ICL) inhibitor with a Mycobacterium tuberculosis IC50 of 134.3 μg/mL. I2906 inhibits the growth of Mycobacterium tuberculosis. I2906 can be used for the research of tuberculosis.
    I2906
  • HY-76648
    NBD-556 333353-44-9 99.57%
    NBD-556, a CD4 mimetic, is a potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction. NBD-556 shows potent cell fusion and virus-cell fusion inhibitory activity at low micromolar levels.
    NBD-556
  • HY-A0246
    Flucloxacillin 5250-39-5 98.02%
    Flucloxacillin is an active antibiotic against gram-positive and gram-negative bacteria.
    Flucloxacillin
  • HY-B0875
    Cefmenoxime hydrochloride 75738-58-8 99.29%
    Cefmenoxime (SCE-1365) hydrochloride is a new semisynthetic cephalosporin antibiotic. Cefmenoxime has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria.
    Cefmenoxime hydrochloride
  • HY-B0947
    Sulfanitran 122-16-7 99.67%
    Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).
    Sulfanitran
  • HY-B1224
    Exalamide 53370-90-4 99.99%
    Exalamide (2-(Hexyloxy)benzamide), an arenecarboxamide, is a potent antifungal agent.
    Exalamide
  • HY-B1309
    Metacetamol 621-42-1 99.97%
    Metacetamol (AMAP) is an analog of Acetaminophen (HY-66005). Metacetamol induces dose-dependent necrosis in primary hepatocytes via glutathione depletion, mitochondrial damage, and formation of mitochondrial protein adducts. Metacetamol derivatives act as anticancer and antibacterial agents. Metacetamol can be used in studies related to breast cancer, bacterial infections, and fungal infections (candidiasis).
    Metacetamol
  • HY-B1407
    Phthalylsulfathiazole 85-73-4
    Phthalylsulfathiazole (N4-Phthalylsulfathiazole) is an orally active sulfonamide intestinal antibacterial agent. Phthalylsulfathiazole has low toxicity and excellent bacteriostatic efficacy. Phthalylsulfathiazole inhibits E. coli, streptococci, staphylococci, and total fecal bacteria. Phthalylsulfathiazole can be used in research related to intestinal infections such as colon infection, bacillary dysentery, and ulcerative colitis.
    Phthalylsulfathiazole
  • HY-B1437
    Acetarsol 97-44-9 98.60%
    Acetarsol (Stovarsol) is a potent and orally active anti-infective agent. Acetarsol shows anti-parasite activity. Acetarsol has the potential for the research of proctitis.
    Acetarsol
  • HY-B1595
    Cefmetazole 56796-20-4 98.82%
    Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections.
    Cefmetazole
  • HY-B1599
    Chloramphenicol palmitate 530-43-8 98.25%
    Chloramphenicol palmitate is an orally active prodrug of Chloramphenicol (HY-B0239), obtained from the esterification reaction between the agent and Palmitic acid (HY-N0830). Chloramphenicol palmitate is rapidly and completely hydrolyzed by intestinal esterase, releasing Chloramphenicol. Chloramphenicol is an orally effective broad-spectrum antibiotic.
    Chloramphenicol palmitate
  • HY-B1781
    Sulfachloropyridazine 80-32-0 99.51%
    Sulfachloropyridazine is a broad spectrum sulfonamide that can be used against both gram-positive and gram-negative aerobic bacteria as well as Chlamydia. Sulfachloropyridazine is also considered as a common pollutant in surface and groundwater. Sulfachloropyridazine via electro-Fenton is a model for sulfonamide antibiotics that are widespread in waters.
    Sulfachloropyridazine
  • HY-B1843
    Fuberidazole 3878-19-1 99.90%
    Fuberidazole (BAY 33172; Furidazole) is a fungicide. Fuberidazole shows a synergistic effect with cucurbituril (CB) macromolecules, such as CB7 and CB8. Studies have shown that, CB8 induces pKa shifts on Fuberidazole. Fuberidazole significantly inhibits the growth of B. cinerea.
    Fuberidazole
  • HY-B1878
    Faltan 133-07-3 98.52%
    Faltan is a dicarboximide fungicide, widely used on vines and several vegetable crops, and is also cytotoxic effect on human bronchial epithelial cells.
    Faltan
  • HY-B1884
    Procymidone 32809-16-8 99.64%
    Procymidone, a pesticide, is an immunogen hapten that can be combined with cOVA (carrier protein) to produce polyclonal antibodies. Procymidone has antifungal activity.
    Procymidone
  • HY-D0948
    Celestine Blue 1562-90-9
    Celestine Blue is a electroactive indicator in DNA biosensors. Celestine Blue is strongly adsorbed on the spinel phases and CNT (carbon nanotubes), facilitates dispersion, acts as a capping agent and allows for the fabrication of spinel decorated CNT. Celestine Blue is an efficient charge transfer mediator, which allows for significant improvement of capacitive behavior. TiO2 nanoparticles doped with Celestine Blue can be used as a label in a sandwich immunoassay for the hepatitis C virus (HCV) core antigen.
    Celestine Blue
  • HY-D1460
    Fluorescein Di-β-D-Glucuronide 134869-04-8
    Fluorescein Di-β-D-Glucuronide is an orally active fluorescent probe substrate and an indicator of β-glucuronidase (βG) activity in intestinal bacteria. Fluorescein Di-β-D-Glucuronide can be used for non-invasive time-lapse optical imaging of βG activity in intestinal bacteria in nude mice. Fluorescein Di-β-D-Glucuronide supports the quantitative analysis of bacterial βG enzyme activity and inhibition.
    Fluorescein Di-β-D-Glucuronide
  • HY-D1543
    Pyronin B 2150-48-3
    Pyronin B is an organic cationic dye used for the staining of bacteria, mycobacteria and ribonucleic acids. Pyronin B is also used as a small hydrophobic (SH) protein channel inhibitor.
    Pyronin B
Cat. No. Product Name / Synonyms Application Reactivity