2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-147097A
    EDA-DA TFA 87156-01-2
    EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    EDA-DA TFA
  • HY-153572A
    Homo-BacPROTAC7 TFA
    Homo-BacPROTAC7 TFA is a PROTAC protein degrader targeting ClpC1/ClpC2 with a Kd of 0.5-2.5 nM for both targets. Homo-BacPROTAC7 (TFA) acts as a bactericidal agent, induces killing of pathogenic mycobacteria, retains activity against dormant-like mycobacterial cells with reduced intracellular ATP levels, and shows elevated antibiotic potency relative to its parent monomer. Homo-BacPROTAC7 (TFA) can be used for the research of tuberculosis.
    Homo-BacPROTAC7 TFA
  • HY-66011AR
    Moxifloxacin (Standard) 151096-09-2 99.72%
    Moxifloxacin (Standard) is the analytical standard of Moxifloxacin. This product is intended for research and analytical applications. Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.
    Moxifloxacin (Standard)
  • HY-A0181S2
    Adenosine monophosphate-d12 dilithium
    Adenosine monophosphate-d12 (AMP-d12) dilithium is deuterium labeled Adenosine monophosphate (HY-A0181). Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction.
    Adenosine monophosphate-d12 dilithium
  • HY-B0275AR
    Oxytetracycline hydrochloride (Standard) 2058-46-0 98.57%
    Oxytetracycline (hydrochloride) (Standard) is the analytical standard of Oxytetracycline (hydrochloride). This product is intended for research and analytical applications. Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity.
    Oxytetracycline hydrochloride (Standard)
  • HY-B0843AR
    Metalaxyl-M (Standard) 70630-17-0
    Metalaxyl-M ((R)-Metalaxyl) (Standard) is the analytical standard of Metalaxyl-M (HY-B0843A). This product is intended for research and analytical applications. Metalaxyl-M ((R)-Metalaxyl) is an orally active and selective inhibitor of fungal RNA polymerase, which exerts fungicidal activity by selectively interfering with the synthesis of fungal ribosomal RNA. Metalaxyl-M can also be used to induce inflammation in hepatocytes and regulate tryptophan metabolism. Metalaxyl-M can be used in ecotoxicology studies.
    Metalaxyl-M (Standard)
  • HY-B1111S1
    Amitraz-d3 99.5%
    Amitraz-d3 is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.
    Amitraz-d3
  • HY-N7057S1
    Nonanoic acid-d3 134646-27-8 99%
    Nonanoic acid (Pelargonic acid)-d3 is the deuterium labeled Nonanoic acid (HY-N7057). Nonanoic acid is a naturally-occurring saturated fatty acid with nine carbon atoms. Nonanoic acid significantly reduces bacterial translocation, enhances antibacterial activity, and remarkably increases the secretion of porcine β-defensins 1 (pBD-1) and pBD-2.
    Nonanoic acid-d3
  • HY-P990233
    Anti-Mouse IFNγR/CD119 Antibody (GR-20)
    Anti-Mouse IFNγR/CD119 Antibody (GR-20) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IFNγR/CD119.Anti-Mouse IFNγR/CD119 Antibody (GR-20) reacts with the mouse IFNγR (interferon gamma receptor) α chain also known as CD119 and IFNγ receptor 1. Anti-Mouse IFNγR/CD119 Antibody (GR-20) blocks the binding of IFNγ to CD119 therefore inhibiting IFNγ signaling. Anti-Mouse IFNγR/CD119 Antibody (GR-20) can be used for the researches of cancer, infection, inflammation and immunology, such as melanoma and C. trachomatis infected genital tract inflammation.
    Anti-Mouse IFNγR/CD119 Antibody (GR-20)
  • HY-P990801
    Anti-Mouse CD11a/LFA-1α Antibody (M17/4)
    Anti-Mouse CD11a/LFA-1α Antibody (M17/4) is an anti-mouse CD11a/LFA-1α IgG2a monoclonal antibody. Anti-Mouse CD11a/LFA-1α Antibody (M17/4) can reduce the recruitment of effector memory CD8 T cells. Anti-Mouse CD11a/LFA-1α Antibody (M17/4) promotes the formation of xenograft tumors by reducing immune rejection reactions. Anti-Mouse CD11a/LFA-1α Antibody (M17/4) can be used for researches on cancer, infection conditions and immunology such as glioblastoma, parasitic and bacterial infections. The recommend isotype control of Anti-Mouse CD11a/LFA-1α Antibody (M17/4): Rat IgG2a kappa, Isotype Control (HY-P990679).
    Anti-Mouse CD11a/LFA-1α Antibody (M17/4)
  • HY-P990861
    Anti-CD4 Antibody (OKT-4)
    Anti-CD4 Antibody (OKT-4) is a kind of mouse IgG2b κ chimeric antibody inhibitor, targeting to human CD4. Anti-CD4 Antibody (OKT-4) can deplete T cells. Anti-CD4 Antibody (OKT-4) can be used for the researches of cancer, infection and immunology, such as melanoma and adenovirus infection.
    Anti-CD4 Antibody (OKT-4)
  • HY-P991059
    VIS-410 2043950-09-8 99%
    VIS-410 is an antibody inhibitor targeting the stem region of hemagglutinin (HA). VIS-410 inhibits influenza virus replication by blocking HA-mediated membrane fusion. VIS-410 exhibits broad-spectrum neutralization against influenza A viruses with group 1 and group 2 hemagglutinins, including subtypes such as H1N1, H3N2, H5N1, and H7N9 (H5N1 IC50 = 1.5 μg/mL). VIS-410 is applicable to research related to influenza A virus infection.
    VIS-410
  • HY-P991450
    ADI-15878 99.80%
    ADI-15878 is a human IgG monoclonal antibody (mAb) targeting Envelope glycoprotein, GP2. ADI-15878 can be used in Ebola virus infection research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
    ADI-15878
  • HY-W004297
    1-Nonadecanol 1454-84-8 99.16%
    1-Nonadecanol is an endogenous metabolite that can be produced by Pantoea agglomerans from Medicago sativa rhizosphere, present in Neotinea ustulata scent and Heracleum thomsonii essential oil. 1-Nonadecanol exerts antimicrobial activity against Streptococcus pneumonia, Klebsiella, and S. aureus. 1-Nonadecanol can be used for the research of bacterial infections and pea aphid infestation.
    1-Nonadecanol
  • HY-W010169
    Sodium 4-aminobenzoate 555-06-6
    Sodium 4-aminobenzoate is an intermediate in the synthesis of folic acid by bacteria, plants and fungi. Sodium 4-aminobenzoate has antibacterial and plant growth regulating properties.
    Sodium 4-aminobenzoate
  • HY-W010252
    N-Benzylethylenediamine 4152-09-4 99.79%
    N-Benzylethylenediamine is a polyamine compound. N-Benzylethylenediamine can effectively release Ca2+ from the outer membrane of Escherichia coli (ED50: 200-500 μM), but cannot induce TPP+ uptake.
    N-Benzylethylenediamine
  • HY-W010254
    4′-Hydroxy-2′-methylacetophenone 875-59-2 99.67%
    4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC50 of 0.65 mM.
    4′-Hydroxy-2′-methylacetophenone
  • HY-W010365
    Rhodanine 141-84-4
    Rhodanine is a selective Echovirus 12 proliferation inhibitor and intermediate. Rhodanine is used to determine tannase activity. Rhodanine can be used in the synthesis of anticancer and antibacterial agents.
    Rhodanine
  • HY-W013158
    Trimethyloctadecylammonium bromide 1120-02-1 98.0%
    Trimethyloctadecylammonium bromide is an inhibitor of dynamin, with an IC50 value of 1.9 μM for dynamin I. Trimethyloctadecylammonium bromide exhibits antibacterial activity against Staphylococcus aureus.
    Trimethyloctadecylammonium bromide
  • HY-W014316
    5-Bromo-5-nitro-1,3-dioxane 30007-47-7 99.89%
    5-Bromo-5-nitro-1,3-dioxane is a broad-spectrum antimicrobial agent active against Gram-positive bacteria, Gram-negative bacteria and fungi. 5-Bromo-5-nitro-1,3-dioxane oxidizes free thiol groups to their corresponding disulfides. 5-Bromo-5-nitro-1,3-dioxane induces intracellular substance leakage in Escherichia coli and Staphylococcus aureus. 5-Bromo-5-nitro-1,3-dioxane modulates the oxygen consumption of Escherichia coli and Staphylococcus aureus.
    5-Bromo-5-nitro-1,3-dioxane
Cat. No. Product Name / Synonyms Application Reactivity